- Inactivating KISS1 Mutation and Hypogonadotropic Hypogonadism
[作者：Topaloglu, AK; Tello, JA; Kotan, LD; Ozbek, MN; Yilmaz, MB; Erdogan, S; Gurbuz, F; Temiz, F; Millar, RP; Yuksel, B,期刊：New England Journal of Medicine, 页码：629-635 , 文章类型： Article，,卷期：2012年366-7]
- Gonadotropin-releasing hormone (GnRH) is the central regulator of gonadotropins, which stimulate gonadal function. Hypothalamic neurons that produce kisspeptin and neurokinin B stimulate GnRH release. Inactivating mutati...
- Intramuscular versus Intravenous Therapy for Prehospital Status Epilepticus
[作者：Silbergleit, R; Durkalski, V; Lowenstein, D; Conwit, R; Pancioli, A; Palesch, Y; Barsan, W,期刊：New England Journal of Medicine, 页码：591-600 , 文章类型： Article，,卷期：2012年366-7]
- BACKGROUND Early termination of prolonged seizures with intravenous administration of benzodiazepines improves outcomes. For faster and more reliable administration, paramedics increasingly use an intramuscular route. ME...
- Semuloparin for Thromboprophylaxis in Patients Receiving Chemotherapy for Cancer
[作者：Agnelli, G; George, DJ; Kakkar, AK; Fisher, W; Lassen, MR; Mismetti, P; Mouret, P; Chaudhari, U; Lawson, F; Turpie, AGG,期刊：New England Journal of Medicine, 页码：601-609 , 文章类型： Article; Proceedings Paper，,卷期：2012年366-7]
- BACKGROUND Patients receiving chemotherapy for cancer are at increased risk for venous thromboembolism. Limited data support the clinical benefit of antithrombotic prophylaxis. METHODS In this double-blind, multicenter t...
- Paraneoplastic Thrombocytosis in Ovarian Cancer
[作者：Stone, RL; Nick, AM; McNeish, IA; Balkwill, F; Han, HD; Bottsford-Miller, J; Rupaimoole, R; Armaiz-Pena, GN; Pecot, CV; Coward, J; Deavers, MT; Vasquez, HG; Urbauer, D; Landen, CN; Hu, W; Gershenson, H; Matsuo, K; Shahzad, MMK; King, ER; Tekedereli, I; Ozpolat, B; Ahn, EH; Bond, VK; Wang, R; Drew, AF; Gushiken, F; Collins, K; DeGeest, K; Lutgendorf, SK; Chiu, W; Lopez-Berestein, G; Afshar-Kharghan, V; Sood, AK,期刊：New England Journal of Medicine, 页码：610-618 , 文章类型： Article，,卷期：2012年366-7]
- BACKGROUND The mechanisms of paraneoplastic thrombocytosis in ovarian cancer and the role that platelets play in abetting cancer growth are unclear. METHODS We analyzed clinical data on 619 patients with epithelial ovari...
- Truncations of Titin Causing Dilated Cardiomyopathy
[作者：Herman, DS; Lam, L; Taylor, MRG; Wang, LB; Teekakirikul, P; Christodoulou, D; Conner, L; DePalma, SR; McDonough, B; Sparks, E; Teodorescu, DL; Cirino, AL; Banner, NR; Pennell, DJ; Graw, S; Merlo, M; Di Lenarda, A; Sinagra, G; Bos, JM; Ackerman, MJ; Mitchell, RN; Murry, CE; Lakdawala, NK; Ho, CY; Barton, PJR; Cook, SA; Mestroni, L; Seidman, JG; Seidman, CE,期刊：New England Journal of Medicine, 页码：619-628 , 文章类型： Article，,卷期：2012年366-7]
- BACKGROUND Dilated cardiomyopathy and hypertrophic cardiomyopathy arise from mutations in many genes. TTN, the gene encoding the sarcomere protein titin, has been insufficiently analyzed for cardiomyopathy mutations beca...
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