Biochemistry————————个性化文献订阅—

Hydrogen Bonding in the Active Site of Ketosteroid Isomerase: Electronic Inductive Effects and Hydrogen Bond Coupling
[作者：Hanoian, P; Sigala, PA; Herschlag, D; Hammes-Schiffer, S,期刊：Biochemistry, 页码：10339-10348 , 文章类型： Article，,卷期：2010年49-48]
Computational studies are performed to analyze the physical properties of hydrogen bonds donated by Tyr16 and Asp103 to a series of substituted phenolate inhibitors bound in the active site of ketosteroid isomerase (KSI)...

In Vitro Interaction between Ceruloplasmin and Human Serum Transferrin
[作者：Ha-Duong, NT; Eid, C; Hemadi, M; Chahine, JME,期刊：Biochemistry, 页码：10261-10263 , 文章类型： Article，,卷期：2010年49-48]
The thermodynamics of the interactions of serum apotransferrin (T) and holotransferrin (TFe2) with ceruloplasmin (Cp), as well as those of human lactoferrin (Lf), were assessed by fluorescence emission spectroscopy. Cp i...

Wiring an [FeFe]-Hydrogenase with Photosystem I for Light-Induced Hydrogen Production
[作者：Lubner, CE; Knorzer, P; Silva, PJN; Vincent, KA; Happe, T; Bryant, DA; Golbeck, JH,期刊：Biochemistry, 页码：10264-10266 , 文章类型： Article，,卷期：2010年49-48]
A molecular wire is used to connect two proteins through their physiologically relevant redox cofactors to facilitate direct electron transfer. Photosystem I (PS I) and an [FeFe]-hydrogenase (H(2)ase) serve as the test b...

Thermodynamics of Cooperative DNA Recognition at a Replication Origin and Transcription Regulatory Site
[作者：Dellarole, M; Sanchez, IE; Gay, GD,期刊：Biochemistry, 页码：10277-10286 , 文章类型： Article，,卷期：2010年49-48]
Binding cooperativity guides the formation of protein-nucleic acid complexes, in particular those that are highly regulated such as replication origins and transcription sites. Using the DNA binding domain of the origin ...

Intrinsically Disordered PEP-19 Confers Unique Dynamic Properties to Apo and Calcium Calmodulin
[作者：Wang, X; Kleerekoper, QK; Xiong, LW; Putkey, JA,期刊：Biochemistry, 页码：10287-10297 , 文章类型： Article，,卷期：2010年49-48]
PEP-19 (Purkinje cell protein 4) is an intrinsically disordered protein with an IQ calmodulin (CaM) binding motif. Expression of PEP-19 was recently shown to protect cells from apoptosis and cell death due to Ca2+ overlo...

The Chemical Basis of Pharmacology
[作者：Keiser, MJ; Irwin, JJ; Shoichet, BK,期刊：Biochemistry, 页码：10267-10276 , 文章类型： Article，,卷期：2010年49-48]
Molecular biology now dominates pharmacology so thoroughly that ills difficult to recall that only a generation ago the field was very different. To understand drug action today, we characterize the targets through which...

Targeting of Protein Phosphatases PP2A and PP2B to the C-Terminus of the L-Type Calcium Channel Ca(v)1.2
[作者：Xu, H; Ginsburg, KS; Hall, DD; Zimmermann, M; Stein, IS; Zhang, MX; Tandan, S; Hill, JA; Horne, MC; Bers, D; Hell, JW,期刊：Biochemistry, 页码：10298-10307 , 文章类型： Article，,卷期：2010年49-48]
The L-type Ca2+ channel Ca(v)1.2 forms macromolecular signaling complexes that comprise the beta(2) adrenergic receptor, trimeric G(s) protein, adenylyl cyclase, and cAMP-dependent protein kinase (PKA) for efficient sign...

Electrophysiology of Respiratory Chain Complexes and the ADP-ATP Exchanger in Native Mitochondrial Membranes
[作者：Watzke, N; Diekert, K; Obrdlik, P,期刊：Biochemistry, 页码：10308-10318 , 文章类型： Article，,卷期：2010年49-48]
Transport or protons and solutes across mitochondrial membranes IS essential for many physiological processes. However, neither the proton-pumping respiratory chain complexes nor the mitochondrial secondary active solute...

Catalytic Role of the Conformational Change in Succinyl-CoA:3-Oxoacid CoA Transferase on Binding CoA
[作者：Fraser, ME; Hayakawa, K; Brown, WD,期刊：Biochemistry, 页码：10319-10328 , 文章类型： Article，,卷期：2010年49-48]
Catalysis by succinyl-CoA:3-oxoacid CoA transferase proceeds through a thioester intermediate in which CoA is covalently linked to the enzyme. To determine the conformation of the thioester intermediate, crystals of the ...

Methaneseleninic Acid Is a Substrate for Truncated Mammalian Thioredoxin Reductase: Implications for the Catalytic Mechanism and Redox Signaling
[作者：Snider, G; Grout, L; Ruggles, EL; Hondal, RJ,期刊：Biochemistry, 页码：10329-10338 , 文章类型： Article，,卷期：2010年49-48]
Mammalian thioredoxin reductase is a homodimeric pyridine nucleotide disulfide oxidoreductase that contains the rare amino acid selenocysteine (Sec) on a C-terminal extension. We previously have shown that a truncated...