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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共21条记录   Modulation of the type I interferon pathways by culture-adaptive hepatitis C virus core mutants [作者：Kang, JI; Kwon, YC; Ahn, BY,期刊：FEBS Letters, 页码：1272-1278 , 文章类型： Article，,卷期：2012年586-9] Hepatitis C virus (HCV) often establishes a persistent infection that leads to chronic liver diseases. The viral core protein modulates various cellular activities involved in this process. We found two mutations, K23E a... Crystal structure of Pyrococcus furiosus PF2050, a member of the DUF2666 protein family [作者：Han, BG; Jeong, KC; Cho, JW; Jeong, BC; Song, HK; Lee, JY; Shin, DH; Lee, S; Lee, BI,期刊：FEBS Letters, 页码：1384-1388 , 文章类型： Article，,卷期：2012年586-9] Pyrococcus furiosus PF2050 is an uncharacterized putative protein that contains two DUF2666 domains. Functional and structural studies of PF2050 have not previously been performed. In this study, we determined the crysta... Peripheral benzodiazepine receptor regulates vascular endothelial activations via suppression of the voltage-dependent anion channel-1 [作者：Joo, HK; Lee, YR; Lim, SY; Lee, EJ; Choi, S; Cho, EJ; Park, MS; Ryoo, S; Park, JB; Jeon, BH,期刊：FEBS Letters, 页码：1349-1355 , 文章类型： Article，,卷期：2012年586-9] Peripheral benzodiazepine receptor (PBR) is a multifunctional protein mainly found on the outer mitochondrial membrane. PBR expression is increased by tumor necrosis factor-alpha (TNF-alpha) in endothelial cells. Adenovi... Depression of mitochondrial metabolism by downregulation of cytoplasmic deacetylase, HDAC6 [作者：Kamemura, K; Ogawa, M; Ohkubo, S; Ohtsuka, Y; Shitara, Y; Komiya, T; Maeda, S; Ito, A; Yoshida, M,期刊：FEBS Letters, 页码：1379-1383 , 文章类型： Article，,卷期：2012年586-9] Mitochondria perform multiple functions critical to the maintenance of cellular homeostasis. Here we report that the downregulation of histone deacetylase 6 (HDAC6) causes a reduction in the net activity of mitochondrial... Phosphoproteomics of Arabidopsis chloroplasts reveals involvement of the STN7 kinase in phosphorylation of nucleoid protein pTAC16 [作者：Ingelsson, B; Vener, AV,期刊：FEBS Letters, 页码：1265-1271 , 文章类型： Article，,卷期：2012年586-9] Light-regulated protein kinases STN7 and STN8 phosphorylate thylakoid membrane proteins and also affect expression of several chloroplast proteins via yet unknown mechanisms. Comparative phosphoproteomics of acetic acid ... PIWIL4 regulates cervical cancer cell line growth and is involved in down-regulating the expression of p14ARF and p53 [作者：Su, C; Ren, ZJ; Wang, F; Liu, M; Li, X; Tang, H,期刊：FEBS Letters, 页码：1356-1362 , 文章类型： Article，,卷期：2012年586-9] Recently, PIWIL4 has been identified as a functional protein involved in tumorigenesis. Cervical cancer is the second most prevalent form of cancer worldwide. The relationship between PIWIL4 and cervical cancer is still ... Epigenetic regulation of 5-lipoxygenase in the phenotypic plasticity of valvular interstitial cells associated with aortic valve stenosis [作者：Nagy, E; Back, M,期刊：FEBS Letters, 页码：1325-1329 , 文章类型： Article，,卷期：2012年586-9] Valvular interstitial cells (VICs) are of mesenchymal origin and may differentiate into immune-like cells. This phenotypic plasticity is a key feature of aortic valve stenosis, but the role of epigenetic mechanisms has n... Expression of the class II tumor suppressor gene RIG1 is directly regulated by p53 tumor suppressor in cancer cell lines [作者：Hsu, TH; Chu, CC; Jiang, SY; Hung, MW; Ni, WC; Lin, HE; Chang, TC,期刊：FEBS Letters, 页码：1287-1293 , 文章类型： Article，,卷期：2012年586-9] Recent studies indicated that the RIG1 (RARRES3/TIG3) plays an important role in cell proliferation, differentiation, and apoptosis. However, the regulatory mechanism of RIG1 gene expression has not been clearly elucidat... Expression, purification and assembly of soluble multimeric MHC class II-invariant chain complexes [作者：Majera, D; Kristan, KC; Neefjes, J; Turk, D; Mihelic, M,期刊：FEBS Letters, 页码：1318-1324 , 文章类型： Article，,卷期：2012年586-9] Major histocompatibility class (MHC) II molecules are essential for running adaptive immune response. They are produced in the ER and targeted to late endosomes with the help of invariant chain (Ii) trimers. Ii trimeriza... Genetic and molecular characterization reveals a unique nucleobase cation symporter 1 in Arabidopsis [作者：Mourad, GS; Tippmann-Crosby, J; Hunt, KA; Gicheru, Y; Bade, K; Mansfield, TA; Schultes, NP,期刊：FEBS Letters, 页码：1370-1378 , 文章类型： Article，,卷期：2012年586-9] Locus At5g03555 encodes a nucleobase cation symporter 1 (AtNCS1) in the Arabidopsis genome. Arabidopsis insertion mutants, AtNcs1-1 and AtNcs1-3, were used for in planta toxic nucleobase analog growth studies and radio-l... Relative intensities of recognition factors at two combining sites of Ralstonia solanacearum lectin (RSL) for accommodating LFuc alpha 1 ->, DMan alpha 1 -> and Gal beta 1 -> 3/4GlcNAc glycotopes [作者：Wu, AM; Liu, JH; Herp, A; Sudakevitz, D; Gilboa-Garber, N,期刊：FEBS Letters, 页码：1294-1299 , 文章类型： Article，,卷期：2012年586-9] Owing to the weak reactivities of monomeric DMan alpha 1 -> and Gal beta 1 -> 3/4GlcNAc beta (I-beta/II beta) glycotopes with Ralstonia solanacearum lectin (RSL), their recognition roles were previously ignored. In this ... ROPGEF1 and ROPGEF4 are functional regulators of ROP11 GTPase in ABA-mediated stomatal closure in Arabidopsis [作者：Li, ZX; Liu, D,期刊：FEBS Letters, 页码：1253-1258 , 文章类型： Article，,卷期：2012年586-9] ROPs constitute a family of plant-specific, RHO-like small GTPases that serve as molecular switches in a wide range of signaling pathways. The activities of ROPs are regulated by guanine nucleotide exchange factors (GEFs... Stability of peptide-HLA-I complexes and tapasin folding facilitation - tools to define immunogenic peptides [作者：Geironson, L; Roder, G; Paulsson, K,期刊：FEBS Letters, 页码：1336-1343 , 文章类型： Article，,卷期：2012年586-9] Only a small fraction of the peptides generated inside the cell end up being presented by HLA-I on the cell surface. High stability of peptide-HLA-I complexes and a low HLA-I tapasin-facilitation have been proposed to pr... SUMOylation of the kainate receptor subunit GluK2 contributes to the activation of the MLK3-JNK3 pathway following kainate stimulation [作者：Zhu, QJ; Xu, Y; Du, CP; Hou, XY,期刊：FEBS Letters, 页码：1259-1264 , 文章类型： Article，,卷期：2012年586-9] Protein SUMOylation has been implicated in the pathogenesis of ischemic stroke. However, the underlying mechanisms remain unclear. Here, we found that global brain ischemia evokes a sustained elevation of GluK2 SUMOylati... Involvement of microRNA-93, a new regulator of PTEN/Akt signaling pathway, in regulation of chemotherapeutic drug cisplatin chemosensitivity in ovarian cancer cells [作者：Fu, X; Tian, J; Zhang, L; Chen, Y; Hao, Q,期刊：FEBS Letters, 页码：1279-1286 , 文章类型： Article，,卷期：2012年586-9] The mechanisms underlying ovarian cancer cell resistance to cisplatin (CDDP) are not fully understood. MicroRNAs (miRNAs) play important roles in tumorigenesis and drug resistance. In this paper, we utilized microRNA arr... Kinetics of proton release and uptake by channelrhodopsin-2 [作者：Nack, M; Radu, I; Schultz, BJ; Resler, T; Schlesinger, R; Bondar, AN; del Val, C; Abbruzzetti, S; Viappiani, C; Bamann, C; Bamberg, E; Heberle, J,期刊：FEBS Letters, 页码：1344-1348 , 文章类型： Article，,卷期：2012年586-9] Electrophysiological experiments showed that the light-activated cation channel channelrhodopsin-2 (ChR2) pumps protons in the absence of a membrane potential. We determined here the kinetics of transient pH change using...