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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共30条记录   Mitochondrial ATP-sensitive potassium channel activity and hypoxic preconditioning are independent of an inwardly rectifying potassium channel subunit in Caenorhabditis elegans [作者：Wojtovich, AP; DiStefano, P; Sherman, T; Brookes, PS; Nehrke, K,期刊：FEBS Letters, 页码：428-434 , 文章类型： Article，,卷期：2012年586-4] Hypoxic preconditioning (HP) is an evolutionarily-conserved mechanism that protects an organism against stress. The mitochondrial ATP-sensitive K+ channel (mK(ATP)) plays an essential role in the protective signaling, bu... MIZ1, an essential protein for root hydrotropism, is associated with the cytoplasmic face of the endoplasmic reticulum membrane in Arabidopsis root cells [作者：Yamazaki, T; Miyazawa, Y; Kobayashi, A; Moriwaki, T; Fujii, N; Takahashi, H,期刊：FEBS Letters, 页码：398-402 , 文章类型： Article，,卷期：2012年586-4] MIZ1 is encoded by a gene essential for root hydrotropism in Arabidopsis. To characterize the property of MIZ1, we used transgenic plants expressing GFP-tagged MIZ1 (MIZ1-GFP) and mutant MIZ1 (MIZ1(G235E)-GFP) in a miz1-... Crystal structure of cce_0566 from Cyanothece 51142, a protein associated with nitrogen fixation in the DUF269 family [作者：Buchko, GW; Robinson, H,期刊：FEBS Letters, 页码：350-355 , 文章类型： Article，,卷期：2012年586-4] The crystal structure for cce_0566 (171 aa, 19.4 kDa), a DUF269 annotated protein from the diazotrophic cyanobacterium Cyanothece sp. ATCC 51142, was determined to 1.60 angstrom resolution. Cce_0566 is a homodimer with e... Novel assay with fluorescence-labelled PrP peptides for differentiating L-type atypical and classical BSEs, and scrapie [作者：Kasai, K; Hirata, A; Ohyama, T; Nokihara, K; Yokoyama, T; Mohri, S,期刊：FEBS Letters, 页码：325-329 , 文章类型： Article，,卷期：2012年586-4] Characteristic differences of prions may account for the conformational diversity of the pathogenic isoform of prion protein (PrPSc). Here, we applied a protein detection procedure by using fluorescent-labelled peptides ... Crystal structures of the coil 2B fragment and the globular tail domain of human lamin B1 [作者：Ruan, JB; Xu, C; Bian, CB; Lam, R; Wang, JP; Kania, J; Min, JR; Zang, JY,期刊：FEBS Letters, 页码：314-318 , 文章类型： Article，,卷期：2012年586-4] We present here the crystal structures of human lamin B1 globular tail domain and coiled 2B domain, which adopt similar folds to Ig-like domain and coiled-coil domain of lamin A, respectively. Despite the overall similar... Cyclin-dependent kinase 4 is a novel target in micoRNA-195-mediated cell cycle arrest in bladder cancer cells [作者：Lin, YW; Wu, J; Chen, H; Mao, YQ; Liu, YF; Mao, QQ; Yang, K; Zheng, XY; Xie, LP,期刊：FEBS Letters, 页码：442-447 , 文章类型： Article，,卷期：2012年586-4] miRNAs are a class of small-noncoding RNAs capable of negatively regulating gene expression. Here, we found that miR-195 is down-regulated in human bladder cancer tissue versus normal adjacent tissue. To better character... PEDV ORF3 encodes an ion channel protein and regulates virus production [作者：Wang, K; Lu, W; Chen, JF; Xie, SQ; Shi, HY; Hsu, HJ; Yu, WJ; Xu, K; Bian, C; Fischer, WB; Schwarz, W; Feng, L; Sun, B,期刊：FEBS Letters, 页码：384-391 , 文章类型： Article，,卷期：2012年586-4] Several studies suggest that the open reading frame 3 (ORF3) gene of porcine epidemic diarrhea virus (PEDV) is related to viral infectivity and pathogenicity, but its function remains unknown. Here, we propose a structur... Phosphate homeostasis in the yeast Saccharomyces cerevisiae, the key role of the SPX domain-containing proteins [作者：Secco, D; Wang, C; Shou, HX; Whelan, J,期刊：FEBS Letters, 页码：289-295 , 文章类型： Review，,卷期：2012年586-4] In the yeast Saccharomyces cerevisiae, a working model for nutrient homeostasis in eukaryotes, inorganic phosphate (Pi) homeostasis is regulated by the PHO pathway, a set of phosphate starvation induced genes, acting to ... Delivery of Bordetella pertussis adenylate cyclase toxin to target cells via outer membrane vesicles [作者：Donato, GM; Goldsmith, CS; Paddock, CD; Eby, JC; Gray, MC; Hewlett, EL,期刊：FEBS Letters, 页码：459-465 , 文章类型： Article，,卷期：2012年586-4] Bordetella pertussis adenylate cyclase toxin (ACT) intoxicates cells by producing intracellular cAMP. B. pertussis outer membrane vesicles (OMV) contain ACT on their surface (OMV-ACT), but the properties of OMV-ACT were ... Phosphosite conservation in single domain orthologs versus paralogs: A way to combine differential regulation with redundant core functions [作者：Huyck, L; Van Troys, M; Ampe, C,期刊：FEBS Letters, 页码：296-302 , 文章类型： Article，,卷期：2012年586-4] Evolutionary conservation for structure function relations is commonly accepted. Here we hypothesize that closely related single domain paralogous proteins, having similar expression profiles and redundant biochemical co... Dimerization, but not phosphothreonine binding, is conserved between the forkhead-associated domains of Drosophila MU2 and human MDC1 [作者：Luo, SK; Ye, KQ,期刊：FEBS Letters, 页码：344-349 , 文章类型： Article，,卷期：2012年586-4] Mutator 2 (MU2) in Drosophila melanogaster has been proposed to be the ortholog of human MDC1, a key mediator in DNA damage response. The forkhead-associated (FHA) domain of MDC1 is a dimerization module regulated by tra... Follistatin-related protein/follistatin-like 1 evokes an innate immune response via CD14 and toll-like receptor 4 [作者：Murakami, K; Tanaka, M; Usui, T; Kawabata, D; Shiomi, A; Iguchi-Hashimoto, M; Shimizu, M; Yukawa, N; Yoshifuji, H; Nojima, T; Ohmura, K; Fujii, T; Umehara, H; Mimori, T,期刊：FEBS Letters, 页码：319-324 , 文章类型： Article，,卷期：2012年586-4] Follistatin-related protein (FRP)/follistatin-like 1 (FSTL1) has multi-specific binding nature especially with TGF-beta superfamily proteins, and thereby modulates organ development. However, its function in immune syste... RUVBL2 is a novel repressor of ARF transcription [作者：Xie, CW; Wang, WY; Yang, F; Wu, M; Mei, YD,期刊：FEBS Letters, 页码：435-441 , 文章类型： Article，,卷期：2012年586-4] ARF is the second most commonly inactivated tumor suppressor behind p53. It has been implicated in the control of cell proliferation, cell senescence, and tumor suppression. However, the detailed mechanism underlying the... Saccharomyces cerevisiae gene YMR291W/TDA1 mediates the in vivo phosphorylation of hexokinase isoenzyme 2 at serine-15 [作者：Kettner, K; Krause, U; Mosler, S; Bodenstein, C; Kriegel, TM; Rodel, G,期刊：FEBS Letters, 页码：455-458 , 文章类型： Article，,卷期：2012年586-4] Hxk2 is the predominant hexokinase of Saccharomyces cerevisiae during growth on glucose. In addition to its role in glycolysis, the enzyme is involved in glucose sensing and regulation of gene expression. Glucose limitat... Human synaptotagmin-II is not a high affinity receptor for botulinum neurotoxin B and G: Increased therapeutic dosage and immunogenicity [作者：Strotmeier, J; Willjes, G; Binz, T; Rummel, A,期刊：FEBS Letters, 页码：310-313 , 文章类型： Article，,卷期：2012年586-4] Botulinum neurotoxins (BoNTs) inhibit neurotransmitter release by hydrolysing SNARE proteins essential for exocytosis. The synaptic vesicle protein synaptotagmin-II of rat and mouse acts as neuronal high affinity recepto... Hypoxia-induced SM22 alpha in A549 cells activates the IGF1R/PI3K/Akt pathway, conferring cellular resistance against chemo- and radiation therapy [作者：Kim, TR; Cho, EW; Paik, SG; Kim, IG,期刊：FEBS Letters, 页码：303-309 , 文章类型： Article，,卷期：2012年586-4] Chemo- or radiation-resistance in tumors caused by hypoxia often undermines efficacy of cancer therapy. Thus, therapies that overcome cellular resistance during hypoxia are necessary. SM22 alpha is an actin-binding prote...