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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共22条记录   Characterization of BshA, bacillithiol glycosyltransferase from Staphylococcus aureus and Bacillus subtilis [作者：Upton, H; Newton, GL; Gushiken, M; Lo, K; Holden, D; Fahey, RC; Rawat, M,期刊：FEBS Letters, 页码：1004-1008 , 文章类型： Article，,卷期：2012年586-7] The first step during bacillithiol (BSH) biosynthesis involves the formation of N-acetylglucosaminylmalate from UDP-N-acetylglucosamine and L-malate and is catalyzed by a GT4 class glycosyltransferase enzyme (BshA). Reco... Clusterin is a specific stabilizer and liberator of extracellular cathepsin K [作者：Novinec, M; Lenarcic, B; Baici, A,期刊：FEBS Letters, 页码：1062-1066 , 文章类型： Article，,卷期：2012年586-7] The cysteine peptidase cathepsin K is a major player in extracellular proteolysis. Here we describe the identification of the multifunctional extracellular chaperone clusterin as a cathepsin K-binding protein. Clusterin ... New phosphate binding sites in the crystal structure of Escherichia coli purine nucleoside phosphorylase complexed with phosphate and formycin A [作者：Stefanic, Z; Narczyk, M; Mikleusevic, G; Wielgus-Kutrowska, B; Bzowska, A; Luic, M,期刊：FEBS Letters, 页码：967-971 , 文章类型： Article，,卷期：2012年586-7] Purine nucleoside phosphorylase (PNP) from Escherichia coli is a homohexamer that catalyses the phosphorolytic cleavage of the glycosidic bond of purine nucleosides. The first crystal structure of the ternary complex of ... Differential usage of NF-kappa B activating signals by IL-1 beta and TNF-alpha in pancreatic beta cells [作者：Ortis, F; Miani, M; Colli, ML; Cunha, DA; Gurzov, EN; Allagnat, F; Chariot, A; Eizirik, DL,期刊：FEBS Letters, 页码：984-989 , 文章类型： Article，,卷期：2012年586-7] The cytokines interleukin (IL)-1 beta and tumor necrosis factor (TNF)-alpha induce beta-cell death in type 1 diabetes via NF-kappa B activation. IL-1 beta induces a more marked NF-kappa B activation than TNF-alpha, with ... Protein folding by 'levels of separation': A hypothesis [作者：Greene, LH; Grant, TM,期刊：FEBS Letters, 页码：962-966 , 文章类型： Article，,卷期：2012年586-7] The protein folding process has been studied both computationally and experimentally for over 30 years. To date there is no detailed mechanism to explain the formation of long-range interactions between the transition an... Human apolipoprotein L1 (ApoL1) in cancer and chronic kidney disease [作者：Hu, CAA; Klopfer, EI; Ray, PE,期刊：FEBS Letters, 页码：947-955 , 文章类型： Review，,卷期：2012年586-7] Human apolipoprotein L1 (ApoL1) possesses both extra-and intra-cellular functions crucial in host defense and cellular homeostatic mechanisms. Alterations in ApoL1 function due to genetic, environmental, and lifestyle fa... The bacterial-type phosphoenolpyruvate carboxylase isozyme from developing castor oil seeds is subject to in vivo regulatory phosphorylation at serine-451 [作者：Dalziel, KJ; O'Leary, B; Brikis, C; Rao, SK; She, YM; Cyr, T; Plaxton, WC,期刊：FEBS Letters, 页码：1049-1054 , 文章类型： Article，,卷期：2012年586-7] Phosphoenolpyruvate carboxylase (PEPC) is a tightly controlled anaplerotic enzyme situated at a pivotal branch point of plant carbohydrate-metabolism. In developing castor oil seeds (COS) a novel allosterically-densensit... The dengue virus M protein localises to the endoplasmic reticulum and forms oligomers [作者：Wong, SS; Haqshenas, G; Gowans, EJ; Mackenzie, J,期刊：FEBS Letters, 页码：1032-1037 , 文章类型： Article，,卷期：2012年586-7] The dengue virus membrane (M) protein is a key component of the mature virion. Here, we characterised the cellular behaviour of M using a recombinant protein construct to understand its inherent properties. Using confoca... The inhibitory effect of miRNA-1 on ET-1 gene expression [作者：Li, D; He, B; Zhang, H; Shan, SF; Liang, Q; Yuan, WJ; Ren, AJ,期刊：FEBS Letters, 页码：1014-1021 , 文章类型： Article，,卷期：2012年586-7] There is a close correlation between endothelin-1 (ET-1) and microRNA-1 (miRNA-1) expression in the heart, but whether ET-1 expression is regulated by miRNA-1 warrants further research. Our results revealed multiple clue... Activating cardiac E2F1 induces up-regulation of pyruvate dehydrogenase kinase 4 in mice on a short term of high fat feeding [作者：Zhang, LY; Mori, J; Wagg, C; Lopaschuk, GD,期刊：FEBS Letters, 页码：996-1003 , 文章类型： Article，,卷期：2012年586-7] A high fat diet (HFD) induces substantial cardiac metabolic alteration(s), but the initiating molecular events remain unclear. We assessed the early cardiac energy metabolic changes in C57/BJ mice fed a HFD for 10 days. ... Metabolic differences underlying two distinct rat urinary phenotypes, a suggested role for gut microbial metabolism of phenylalanine and a possible connection to autism [作者：Clayton, TA,期刊：FEBS Letters, 页码：956-961 , 文章类型： Article，,卷期：2012年586-7] A novel explanation is proposed for the metabolic differences underlying two distinct rat urinary compositional phenotypes i.e. that these may arise from differences in the gut microbially-mediated metabolism of phenylal... TLR-induced NF-kappa B activation regulates NLRP3 expression in murine macrophages [作者：Qiao, Y; Wang, P; Qi, JN; Zhang, L; Gao, CJ,期刊：FEBS Letters, 页码：1022-1026 , 文章类型： Article，,卷期：2012年586-7] NLRP3 inflammasome plays a critical role in the activation of caspase-1 and maturation of IL-1 beta. However, the specific cis- and trans-regulatory elements that determine the extent of NLRP3 expression are not well def... Tumor suppressor RBM5 directly interacts with the DExD/H-box protein DHX15 and stimulates its helicase activity [作者：Niu, ZY; Jin, WX; Zhang, LB; Li, XL,期刊：FEBS Letters, 页码：977-983 , 文章类型： Article，,卷期：2012年586-7] RNA binding motif protein 5 (RBM5) is a candidate tumor suppressor gene. Recent studies showed that RBM5 functions as an alternative splicing regulator of apoptosis-related genes. Here, we identify DHX15 and PRP19, two s... UGT75L6 and UGT94E5 mediate sequential glucosylation of crocetin to crocin in Gardenia jasminoides [作者：Nagatoshi, M; Terasaka, K; Owaki, M; Sota, M; Inukai, T; Nagatsu, A; Mizukami, H,期刊：FEBS Letters, 页码：1055-1061 , 文章类型： Article，,卷期：2012年586-7] Crocin is an apocarotenoid glycosyl ester accumulating in fruits of Gardenia jasminoides and used as a food coloring and nutraceutical. For the first time, the two glucosyltransferases UGT75L6 and UGT94E5 that sequential... Asymmetric states of vitamin B-12 transporter BtuCD are not discriminated by its cognate substrate binding protein BtuF [作者：Korkhov, VM; Mireku, SA; Hvorup, RN; Locher, KP,期刊：FEBS Letters, 页码：972-976 , 文章类型： Article，,卷期：2012年586-7] BtuCD is an ABC transporter catalyzing the uptake of vitamin B-12 across the Escherichia coli inner membrane. A previously reported X-ray structure of BtuCD in complex with the periplasmic vitamin B-12-binding protein Bt... Atomic resolution of the crystal structure of the hyperthermophilic family 12 endocellulase and stabilizing role of the DxDxDG calcium-binding motif in Pyrococcus furiosus [作者：Kim, HW; Kataoka, M; Ishikawa, K,期刊：FEBS Letters, 页码：1009-1013 , 文章类型： Article，,卷期：2012年586-7] Hyperthermophilic glycoside hydrolase family 12 endocellulase (EGPf) from the archaeon Pyrococcus furiosus catalyzes the hydrolytic cleavage of beta-1,4-glucosidic linkage in beta-glucan cellulose. A truncated EGPf (EGPf...