- Phosphorylation of Akt/GSK-3 beta/eNOS amplifies 5-HT2B receptor blockade mediated anti-hypertrophic effect in rats
[作者：Bharti, S; Singh, R; Chauhan, SS; Hussain, T; Al-Attas, OS; Arya, DS,期刊：FEBS Letters, 页码：180-185 , 文章类型： Article，,卷期：2012年586-2]
- Herein, we studied the cross talk between 5-HT2B receptor blocker (SB-204741) and GSK-3 beta inhibitor (SB-216763) in isoproterenol-induced cardiac hypertrophy for 28 days. SB-204741 treatment significantly ameliorated (...
- Discovery of a novel enzymatic cleavage site for botulinum neurotoxin F5
[作者：Kalb, SR; Baudys, J; Webb, RP; Wright, P; Smith, TJ; Smith, LA; Fernandez, R; Raphael, BH; Maslanka, SE; Pirkle, JL; Barr, JR,期刊：FEBS Letters, 页码：109-115 , 文章类型： Article，,卷期：2012年586-2]
- Botulinum neurotoxins (BoNTs) cause botulism by cleaving proteins necessary for nerve transmission. There are seven serotypes of BoNT, A-G, characterized by their response to antisera. Many serotypes are further distingu...
- Dissociation of the insulin receptor from caveolae during TNF alpha-induced insulin resistance and its recovery by D-PDMP
[作者：Sekimoto, J; Kabayama, K; Gohara, K; Inokuchi, J,期刊：FEBS Letters, 页码：191-195 , 文章类型： Article，,卷期：2012年586-2]
- Previously, we demonstrated that an inhibitor of ganglioside biosynthesis, D-PDMP, could restore impaired insulin signaling in tumor necrosis factor a (TNF alpha)-treated adipocytes by blocking the increase of GM3 gangli...
- Double-stranded RNA induces S100 gene expression by a cycloheximide-sensitive factor
[作者：Voss, A; Gescher, K; Hensel, A; Nacken, W; Zanker, KS; Kerkhoff, C,期刊：FEBS Letters, 页码：196-203 , 文章类型： Article，,卷期：2012年586-2]
- Viral double-stranded RNA (dsRNA) and its synthetic analog polyI:C are recognized via multiple pathways and induce the expression of genes related to inflammation. In the present study, we demonstrated the polyI: C-induc...
- Effect of N-homocysteinylation on physicochemical and cytotoxic properties of amyloid beta-peptide
[作者：Khodadadi, S; Riazi, GH; Ahmadian, S; Hoveizi, E; Karima, O; Aryapour, H,期刊：FEBS Letters, 页码：127-131 , 文章类型： Article，,卷期：2012年586-2]
- Hyperhomocysteinemia has recently been identified as an important risk factor for Alzheimer's disease (AD). One of the potential mechanisms underlying harmful effects of homocysteine (Hcy) is site-specific acylation of p...
- Formation of supramolecular structures of a native-like protein in the presence of amphiphilic peptides: Variations in aggregate morphology
[作者：Artemova, N; Stein-Margolina, V; Smirnova, E; Gurvits, B,期刊：FEBS Letters, 页码：186-190 , 文章类型： Article，,卷期：2012年586-2]
- A striking potential of the amphiphilic dipeptides, Arg-Phe or Asp-Phe, to induce aggregation of a model protein, alcohol dehydrogenase in its native-like state, has been demonstrated under physiologically relevant condi...
- Geranyl modification on the tryptophan residue of ComX(RO-E-2) pheromone by a cell-free system
[作者：Tsuji, F; Ishihara, A; Kurata, K; Nakagawa, A; Okada, M; Kitamura, S; Kanamaru, K; Masuda, Y; Murakami, K; Irie, K; Sakagami, Y,期刊：FEBS Letters, 页码：174-179 , 文章类型： Article，,卷期：2012年586-2]
- ComX pheromone is an isoprenoidal oligopeptide containing a modified tryptophan residue, which stimulates natural genetic competence in the gram-positive bacterium Bacillus. Since posttranslational prenylation on the try...
- Specific nitration of tyrosines 46 and 48 makes cytochrome c assemble a non-functional apoptosome
[作者：Garcia-Heredia, JM; Diaz-Moreno, I; Diaz-Quintana, A; Orzaez, M; Navarro, JA; Hervas, M; De la Rosa, MA,期刊：FEBS Letters, 页码：154-158 , 文章类型： Article，,卷期：2012年586-2]
- Under nitroxidative stress, a minor fraction of cytochrome c can be modified by tyrosine nitration. Here we analyze the specific effect of nitration of tyrosines 46 and 48 on the dual role of cytochrome c in cell surviva...
- Interaction of protein inhibitor of activated STAT 2 (PIAS2) with receptor of activated C kinase 1, RACK1
[作者：Zheng, Y; Zhang, LP; Jia, XQ; Wang, HY; Hu, YQ,期刊：FEBS Letters, 页码：122-126 , 文章类型： Article，,卷期：2012年586-2]
- In this study, the evolutionarily conserved intracellular adaptor protein, receptor of activated C kinase 1 (RACK1) was identified as a novel interaction partner of protein inhibitor of activated STAT 2 (PIAS2) using a y...
- 14-3-3 sigma regulation by p53 mediates a chemotherapy response to 5-fluorouracil in MCF-7 breast cancer cells via Akt inactivation
[作者：Zheng, GP; Xiong, Y; Yi, SS; Zhang, WJ; Peng, B; Zhang, Q; He, ZM,期刊：FEBS Letters, 页码：163-168 , 文章类型： Article，,卷期：2012年586-2]
- We previously demonstrated that 14-3-3 sigma was downregulated in 5-fluorouracil (5-Fu)-resistant MCF-7 breast cancer cells (MCF-7/5-Fu). Here, we found that stably enhanced 14-3-3 sigma expression strengthened the effec...
- The cytosolic domain of human Tom22 modulates human Bax mitochondrial translocation and conformation in yeast
[作者：Renault, TT; Grandier-Vazeille, X; Arokium, H; Velours, G; Camougrand, N; Priault, M; Teijido, O; Dejean, LM; Manon, S,期刊：FEBS Letters, 页码：116-121 , 文章类型： Article，,卷期：2012年586-2]
- The role of the mitochondrial protein receptor Tom22p in the interaction of pro-apoptotic protein Bax with yeast mitochondria was investigated. Co-immunoprecipitation assays showed that human Bax interacted with differen...
- A novel family of toxin/antitoxin proteins in Bacillus species
[作者：Holberger, LE; Garza-Sanchez, F; Lamoureux, J; Low, DA; Hayes, CS,期刊：FEBS Letters, 页码：132-136 , 文章类型： Article，,卷期：2012年586-2]
- The C-terminal regions (CT) of Pfam PF04740 proteins share significant sequence identity with the toxic CdiA-CT effector domains of contact-dependent growth inhibition (CDI) systems. In accord with this homology, we find...
- Acetylation-dependent regulation of mitochondrial ALDH2 activation by SIRT3 mediates acute ethanol-induced eNOS activation
[作者：Xue, L; Xu, F; Meng, LJ; Wei, SJ; Wang, JL; Hao, PP; Bian, Y; Zhang, Y; Chen, YG,期刊：FEBS Letters, 页码：137-142 , 文章类型： Article，,卷期：2012年586-2]
- Moderate alcohol consumption has beneficial effects on endothelial nitric-oxide synthase (eNOS) activation, which can engender an array of anti-atherogenic actions. Here we show that in human aortic endothelial cells (HA...
- The yeast metacaspase is implicated in oxidative stress response in frataxin-deficient cells
[作者：Lefevre, S; Sliwa, D; Auchere, F; Brossas, C; Ruckenstuhl, C; Boggetto, N; Lesuisse, E; Madeo, F; Camadro, JM; Santos, R,期刊：FEBS Letters, 页码：143-148 , 文章类型： Article，,卷期：2012年586-2]
- Friedreich ataxia is the most common recessive neurodegenerative disease and is caused by reduced expression of mitochondrial frataxin. Frataxin depletion causes impairment in iron-sulfur cluster and heme biosynthesis, d...
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