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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共31条记录   Molecular Dynamics Simulation of Ester-Linked Hen Egg White Lysozyme Reveals the Effect of Missing Backbone Hydrogen Bond Donors on the Protein Structure [作者：Eichenberger, AP; Gattin, Z; Yalak, G; van Gunsteren, WF,期刊：Helvetica Chimica Acta, 页码：1857-1869 , 文章类型： Article，,卷期：2010年93-10] The three-dimensional structure of a protein is stabilized by a number of different atomic interactions. One of these is hydrogen bonding. Its influence on the spatial structure of the hen egg white lysozyme is investiga... The Effect of Fluoro Substitution upon the beta-Hairpin Fold of a beta-Tetrapeptide in Methanol [作者：Bachmann, S; Jaun, B; van Gunsteren, WF; Wang, DQ,期刊：Helvetica Chimica Acta, 页码：1870-1881 , 文章类型： Article，,卷期：2010年93-10] The importance of beta-peptides lies in their ability to mimic the conformational behavior of alpha-peptides, even with a much shorter chain length, and in their resistance to proteases. To investigate the effect of subs... Enzyme-Catalyzed Stereoselective Synthesis of Two Novel Carbasugar Derivatives [作者：Gumus, A; Tanyeli, C,期刊：Helvetica Chimica Acta, 页码：1882-1893 , 文章类型： Article，,卷期：2010年93-10] Enzymatic resolution of racemic 1,4,5,6-tetrachloro-2-(hydroxymethyl)-7,7-dimethoxybicyclo[2.2.1]hept-5-ene (rac-1) using various lipases in vinyl acetate as acetyl source was studied. The obtained enantiomerically enric... Alkylation Reactions at the Benzo Moiety of 2,4-Dimethoxy-3-(phenylsulfonyl)benzo[a]heptalenes - Model Compounds of Colchicinoids [作者：El Rayes, S; Linden, A; Abou-Hadeed, K; Hansen, HJ,期刊：Helvetica Chimica Acta, 页码：1894-1911 , 文章类型： Article，,卷期：2010年93-10] Alkylation reactions of 3-(X-sulfonyl)benzo[a]heptalene-2,4-diols (X=Ph, morpholin-4-yl) and their dimethyl ethers were studied. The diols form with K2CO3/MeI in aqueous media the 1-methylated benzoheptalenes, but in yie... Synthesis and Redox Behavior of Novel 9,10-Diphenylphenanthrenes [作者：Schreivogel, A; Sieger, M; Baro, A; Laschat, S,期刊：Helvetica Chimica Acta, 页码：1912-1924 , 文章类型： Article，,卷期：2010年93-10] The synthesis and electrochemical investigations of 9,10-diphenylphenanthrene 2a and its derivatives 2b-2e are reported. The cyclic voltammetry of derivatives 2a-2e and 2e in different solvent/Bu4NPF6 electrolyte systems... Artabotryols A-E, New Lanostane Triterpenes from the Seeds of Artabotrys odoratissimus [作者：Gupta, C; Prasad, S; Sahai, M; Asai, T; Hara, N; Fujimoto, Y,期刊：Helvetica Chimica Acta, 页码：1925-1932 , 文章类型： Article，,卷期：2010年93-10] Six new lanostane triterpenes, artabotryols A, B, Cl, C2, D, and E (1, 2, 3a, 3b, 4, and 5, resp.) have been isolated from the seeds of Artabotrys odoratissimus (Annonaceae). Their structures have been established as (3 ... Synthesis of Pteroenone and Its Stereoisomers, a Defensive Metabolite of the Abducted Antarctic Pteropod Clione antarctica [作者：Asao, H; Nakamura, Y; Furuya, Y; Kuwahara, S; Baker, BJ; Kiyota, H,期刊：Helvetica Chimica Acta, 页码：1933-1944 , 文章类型： Article，,卷期：2010年93-10] Four stereoisomers of (+)-pteroenone, a defensive metabolite of the abducted Antarctic pteropod Clone antarctica, were synthesized by employing anti-/syn-selective aldol reactions as the key step. These compounds display... Chemical and Genetic Study of Ligularia anoleuca and L. veitchiana in Yunnan and Sichuan Provinces of China [作者：Nagano, H; Kanda, M; Yamada, H; Hanai, R; Gong, X; Kuroda, C,期刊：Helvetica Chimica Acta, 页码：1945-1952 , 文章类型： Article，,卷期：2010年93-10] Chemical and genetic study of Ligularia anoleuca and L. veitchiana, which belong to section Ligularia, series Speciosae, was carried out. From L. anoleuca samples, collected in Yunnan and Sichuan Provinces of China, a ne... New Sesquiterpenes from the Flowers of Chrysanthemum indicum L. [作者：Bi, YF; Jia, L; Shi, SP; Sun, XL; Chen, YY; Zhang, YB,期刊：Helvetica Chimica Acta, 页码：1953-1959 , 文章类型： Article，,卷期：2010年93-10] Two new guaianolides (= guaianolactones), chrysanthguaianolactone A and B (1 and 2, resp.), and one new eudesmane sesquiterpene, chrysanthemdiol A (6), together with seven known sesquiterpenes were isolated from the flow... Stereoselective Total Synthesis of Dodoneine [作者：Chinnababu, B; Reddy, SP; Rao, CB; Rajesh, K; Venkateswarlu, Y,期刊：Helvetica Chimica Acta, 页码：1960-1966 , 文章类型： Article，,卷期：2010年93-10] A simple and highly efficient stereoselective total synthesis of dodoneine (1), a naturally occurring bioactive 5,6-dihydro-2H-pyran-2-one, was achieved. The synthesis involved Keck's asymmetric allylation, iodine-induce... Microwave-Assisted Synthesis of Novel 2,4-Dihydro-5-[4-(trifluoromethyl)phenyl]-3H-1,2,4-triazol-3-ones and Potentiometric Determination of Their pK(a) in Nonaqueous Solvents [作者：Ozil, M; Islamoglu, F; Mentese, E; Kahveci, B,期刊：Helvetica Chimica Acta, 页码：1967-1974 , 文章类型： Article，,卷期：2010年93-10] The novel 4-amino- or 4-aryl-substituted 2,4-dihydro-5-[(4-trifluoromethyl)phenyl]-3H-1,2,4-triazol-3-ones 3a-3g were synthesized by reaction of N-(ethoxycarbonyl)-4-(trifluoromethyl)benzenehydrazonic acid ethyl ester (2... Four New Nortriterpenoids from Schisandra lancifolia [作者：Xiao, WL; Wu, YL; Shang, SZ; He, F; Luo, XA; Yang, GY; Pu, JX; Chen, GQ; Sun, HD,期刊：Helvetica Chimica Acta, 页码：1975-1982 , 文章类型： Article，,卷期：2010年93-10] Four new highly oxygenated nortriterpenoids, lancifodilactones O-R (1-4), together with six known ones, i.e., 5-10, were isolated from the leaves and stems of Schisandra lancifolia. Their structures were elucidated by sp... Eremophilane Sesquiterpenoids from Ligularia fischeri [作者：Xie, WD; Weng, CW; Li, X; Row, KH,期刊：Helvetica Chimica Acta, 页码：1983-1989 , 文章类型： Article，,卷期：2010年93-10] A novel eremophilane duller, named as fischelactone, and a new sesquiterpene lactam, eremophila-1(10),7(11),8-triene-12,8-lactam, along with ten known compounds, were isolated from the roots of Ligularia fischeri. Their ... Lewis Acids as Mild and Effective Catalysts for the Synthesis of 3,5-Bis[(hetero)arylidene]biperidin-4-ones [作者：Leonova, E; Makarov, M; Klemenkova, Z; Odinets, I,期刊：Helvetica Chimica Acta, 页码：1990-1999 , 文章类型： Article，,卷期：2010年93-10] The aldol-crotonic condensation reactions of N-alkyl- and NH-piperidin-4-one derivatives with (hetero)aromatic aldehydes promoted by Lewis acids or bases were examined. This comparative study has revealed three effective... New Sesquiterpenoids from Artemisia anomala [作者：Zan, K; Shi, SP; Fu, QA; Chen, XQ; Zhou, SX; Xiao, MT; Tu, PF,期刊：Helvetica Chimica Acta, 页码：2000-2006 , 文章类型： Article，,卷期：2010年93-10] One new guaianolide, anomalactone A (1), and one new norcadinane sesquiterpene, anomallenodiol (2), along with two germacranolides, anomalactones B and C (3 and 4, resp.), were isolated from the aerial part of Artemisia ... Pentacyclic Triterpenoid Saponins from Silene viscidula [作者：Xu, W; Wu, JM; Zhu, Z; Sha, Y; Fang, J; Li, YS,期刊：Helvetica Chimica Acta, 页码：2007-2014 , 文章类型： Article，,卷期：2010年93-10] Three new pentacyclic triterpenoid saponins, viscidulosides A and B (1 and 2, resp.), and silenoviscoside D (3), were isolated from the roots of Silens viscidula, together with two known saponins, sinocrassulosides VIII ...