- Peroxisome-proliferator-activated receptor gamma (PPAR gamma) is required for modulating endothelial inflammatory response through a nongenomic mechanism
[作者:Cantini, G; Lombardi, A; Borgogni, E; Francalanci, M; Ceni, E; Degl'Innocenti, S; Gelmini, S; Poli, G; Galli, A; Serio, M; Forti, G; Luconi, M,期刊:European Journal of Cell Biology, 页码:645-653 , 文章类型: Article,,卷期:2010年89-9]
- Besides their well-known anti-diabetic effects, the peroxisome-proliferator-activated receptor gamma (PPAR gamma) thiazolidinedione ligands (TZD) have been suggested to also display anti-inflammatory properties. The rece...
- The structure of invadopodia in a complex 3D environment
[作者:Tolde, O; Rosel, D; Vesely, P; Folk, P; Brabek, J,期刊:European Journal of Cell Biology, 页码:674-680 , 文章类型: Article,,卷期:2010年89-9]
- Invadopodia and podosomes have been intensively studied because of their involvement in the degradation of extracellular matrix. As both structures have been studied mostly on thin matrices, their commonly reported shape...
- Studies on the morphology and spreading of human endothelial cells define key inter- and intramolecular interactions for talin1
[作者:Kopp, PM; Bate, N; Hansen, TM; Brindle, NPJ; Praekelt, U; Debrand, E; Coleman, S; Mazzeo, D; Goult, BT; Gingras, AR; Pritchard, CA; Critchley, DR; Monkley, SJ,期刊:European Journal of Cell Biology, 页码:661-673 , 文章类型: Article,,卷期:2010年89-9]
- Talin binds to and activates integrins and is thought to couple them to cytoskeletal actin. However, functional studies on talin have been restricted by the fact that most cells express two talin isoforms. Here we show t...
- Initial receptor-ligand interactions modulate gene expression and phagosomal properties during both early and late stages of phagocytosis
[作者:Hoffmann, E; Marion, S; Mishra, BB; John, M; Kratzke, R; Ahmad, SF; Holzer, D; Anand, PK; Weiss, DG; Griffiths, G; Kuznetsov, SA,期刊:European Journal of Cell Biology, 页码:693-704 , 文章类型: Article,,卷期:2010年89-9]
- The receptors engaged during recognition and phagocytic uptake of microorganisms and particles influence signaling events and diverse subcellular responses that occur during phagosome formation and maturation. However, p...
- The sarcomeric Z-disc component myopodin is a multiadapter protein that interacts with filamin and alpha-actinin
[作者:Linnemann, A; van der Ven, PFM; Vakeel, P; Albinus, B; Simonis, D; Bendas, G; Schenk, JA; Micheel, B; Kley, RA; Furst, DO,期刊:European Journal of Cell Biology, 页码:681-692 , 文章类型: Article,,卷期:2010年89-9]
- Here we introduce myopodin as a novel filamin C binding partner. Corroborative yeast two-hybrid and biochemical analyses indicate that the central part of myopodin that shows high homology to the closely related protein ...
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