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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共16条记录   An Old Player on a New Playground: Bmi-1 as a Regulator of Prostate Stem Cells [作者：Laffin, B; Tang, DG,期刊：Cell Stem Cell, 页码：639-640 , 文章类型： Editorial Material，,卷期：2010年7-6] The polycomb group transcriptional repressor Bmi-1 regulates both normal and cancer stem cells in multiple tissues. In this issue of Cell Stem Cell, Lukacs et al. (2010) report that Bmi-1 also regulates the self-renewal ... Another Horse in the Meta-Stable State of Pluripotency [作者：Cherry, A; Daley, GQ,期刊：Cell Stem Cell, 页码：641-642 , 文章类型： Editorial Material，,卷期：2010年7-6] Reports of heterogeneity within embryonic stem cell lines suggest that pluripotent stem cells captured in culture may be less homogeneous than previously assumed. In a recent issue of Cell, Scholer and colleagues (Han et... A Bipotent Mesoderm Subset Identified via Colony-Forming Assay [作者：Yoder, MC,期刊：Cell Stem Cell, 页码：643-644 , 文章类型： Editorial Material，,卷期：2010年7-6] The use of an in vitro colony-forming assay has previously led to identification of a mesoderm-derived bipotent hemangioblast from differentiating hESCs. In this issue of Cell Stem Cell, Vodyanik et al. have used a simil... HSPCs in the Balance: The Vascular Niche [作者：Boyerinas, B; Sipkins, DA,期刊：Cell Stem Cell, 页码：645-646 , 文章类型： Editorial Material，,卷期：2010年7-6] Recently, in Nature Cell Biology, Kobayashi et al. (2010) report that Akt-activated sinusoidal endothelial cells within the bone marrow modulate the self-renewal and differentiation of hematopoietic stem cells. This find... Restraining Stem Cell Niche Plasticity: A New Talent of Eph Receptors [作者：Murai, KK; Pasquale, EB,期刊：Cell Stem Cell, 页码：647-648 , 文章类型： Editorial Material，,卷期：2010年7-6] Multiple Eph receptor tyrosine kinases and ephrin ligands are expressed in stem cells and their niches, where their complex roles are under intense investigation. Nomura et al. (2010) reveal an unexpected function of Eph... Noncoding RNA Landmarks of Pluripotency and Reprogramming [作者：Ouyang, ZQ; Zheng, GXY; Chang, HY,期刊：Cell Stem Cell, 页码：649-650 , 文章类型： Editorial Material，,卷期：2010年7-6] Noncoding RNAs have emerged as important determinants of pluripotency and reprogramming. In this issue of Cell Stem Cell, Kosik and colleagues now provide a detailed map of microRNA expression patterns to infer the biolo... Reprogramming of Human Primary Somatic Cells by OCT4 and Chemical Compounds [作者：Zhu, SY; Li, WL; Zhou, HY; Wei, WG; Ambasudhan, R; Lin, TX; Kim, J; Zhang, K; Ding, S,期刊：Cell Stem Cell, 页码：651-655 , 文章类型： Article，,卷期：2010年7-6] Tissue-Resident Adult Stem Cell Populations of Rapidly Self-Renewing Organs [作者：Barker, N; Bartfeld, S; Clevers, H,期刊：Cell Stem Cell, 页码：656-670 , 文章类型： Review，,卷期：2010年7-6] The epithelial lining of the intestine, stomach, and skin is continuously exposed to environmental assault, imposing a requirement for regular self-renewal. Resident adult stem cell populations drive this renewal, and mu... MicroRNA Profiling Reveals Two Distinct p53-Related Human Pluripotent Stem Cell States [作者：Neveu, P; Kye, MJ; Qi, SP; Buchholz, DE; Clegg, DO; Sahin, M; Park, IH; Kim, KS; Daley, GQ; Kornblum, HI; Shraiman, BI; Kosik, KS,期刊：Cell Stem Cell, 页码：671-681 , 文章类型： Article，,卷期：2010年7-6] Reprogramming methodologies have provided multiple routes for achieving pluripotency. However, pluripotency is generally considered to be an almost singular state, with subtle differences described between induced plurip... Bmi-1 Is a Crucial Regulator of Prostate Stem Cell Self-Renewal and Malignant Transformation [作者：Lukacs, RU; Memarzadeh, S; Wu, H; Witte, ON,期刊：Cell Stem Cell, 页码：682-693 , 文章类型： Article，,卷期：2010年7-6] The Polycomb group transcriptional repressor Bmi-1 is often upregulated in prostate cancer, but its functional roles in prostate stem cell maintenance and prostate cancer are unclear. Loss- and gain-of-function analysis ... miR-130b Promotes CD133(+) Liver Tumor-Initiating Cell Growth and Self-Renewal via Tumor Protein 53-Induced Nuclear Protein 1 [作者：Ma, S; Tang, KH; Chan, YP; Lee, TK; Kwan, PS; Castilho, A; Ng, I; Man, K; Wong, N; To, KF; Zheng, BJ; Lai, PBS; Lo, CM; Chan, KW; Guan, XY,期刊：Cell Stem Cell, 页码：694-707 , 文章类型： Article，,卷期：2010年7-6] A novel paradigm in tumor biology suggests that cancer growth is driven by stem-like cells within a tumor, called tumor-initiating cells (TICs) or cancer stem cells (CSCs). Here we describe the identification and charact... TIM-3 Is a Promising Target to Selectively Kill Acute Myeloid Leukemia Stem Cells [作者：Kikushige, Y; Shima, T; Takayanagi, S; Urata, S; Miyamoto, T; Iwasaki, H; Takenaka, K; Teshima, T; Tanaka, T; Inagaki, Y; Akashi, K,期刊：Cell Stem Cell, 页码：708-717 , 文章类型： Article，,卷期：2010年7-6] Acute myeloid leukemia (AML) originates from self-renewing leukemic stem cells (LSCs), an ultimate therapeutic target for AML. Here we identified T cell immunoglobulin mucin-3 (TIM-3) as a surface molecule expressed on L... A Mesoderm-Derived Precursor for Mesenchymal Stem and Endothelial Cells [作者：Vodyanik, MA; Yu, JY; Zhang, X; Tian, SL; Stewart, R; Thomson, JA; Slukvin, II,期刊：Cell Stem Cell, 页码：718-729 , 文章类型： Article，,卷期：2010年7-6] Among the three embryonic germ layers, the mesoderm is a major source of the mesenchymal precursors giving rise to skeletal and connective tissues, but these precursors have not previously been identified and characteriz... EphB Signaling Controls Lineage Plasticity of Adult Neural Stem Cell Niche Cells [作者：Nomura, T; Goritz, C; Catchpole, T; Henkemeyer, M; Frisen, J,期刊：Cell Stem Cell, 页码：730-743 , 文章类型： Article，,卷期：2010年7-6] Stem cells remain in specialized niches over the life-span of the organism in many organs to ensure tissue homeostasis and enable regeneration. How the niche is maintained is not understood, but is probably as important ... In Vivo Fate Mapping and Expression Analysis Reveals Molecular Hallmarks of Prospectively Isolated Adult Neural Stem Cells [作者：Beckervordersandforth, R; Tripathi, P; Ninkovic, J; Bayam, E; Lepier, A; Stempfhuber, B; Kirchhoff, F; Hirrlinger, J; Haslinger, A; Lie, DC; Beckers, J; Yoder, B; Irmler, M; Gotz, M,期刊：Cell Stem Cell, 页码：744-758 , 文章类型： Article，,卷期：2010年7-6] Until now, limitations in the ability to enrich adult NSCs (aNSCs) have hampered meaningful analysis of these cells at the transcriptome level. Here we show via a split-Cre technology that coincident activity of the hGFA... Different Flavors of Pluripotency, Molecular Mechanisms, and Practical Implications (vol 7, pg 559, 2010) [作者：Buecker, C; Geijsen, N,期刊：Cell Stem Cell, 页码：759-759 , 文章类型： Correction，,卷期：2010年7-6]