- Adult SVZ Lineage Cells Home to and Leave the Vascular Niche via Differential Responses to SDF1/CXCR4 Signaling
[作者：Kokovay, E; Goderie, S; Wang, Y; Lotz, S; Lin, G; Sun, Y; Roysam, B; Shen, Q; Temple, S,期刊：Cell Stem Cell, 页码：163-173 , 文章类型： Article，,卷期：2010年7-2]
- Neural progenitor cells (NPCs) in the adult subventricular zone (SVZ) are associated with ependymal and vasculature niches, which regulate stem cell self-renewal and differentiation. Activated Type B stem cells and their...
- Hematopoietic Stem Cell Quiescence Promotes Error-Prone DNA Repair and Mutagenesis
[作者：Mohrin, M; Bourke, E; Alexander, D; Warr, MR; Barry-Holson, K; Le Beau, MM; Morrison, CG; Passegue, E,期刊：Cell Stem Cell, 页码：174-185 , 文章类型： Article，,卷期：2010年7-2]
- Most adult stem cells, including hematopoietic stem cells (HSCs), are maintained in a quiescent or resting state in vivo. Quiescence is widely considered to be an essential protective mechanism for stem cells that minimi...
- Transient Inactivation of Rb and ARF Yields Regenerative Cells from Postmitotic Mammalian Muscle
[作者：Pajcini, KV; Corbel, SY; Sage, J; Pomerantz, JH; Blau, HM,期刊：Cell Stem Cell, 页码：198-213 , 文章类型： Article，,卷期：2010年7-2]
- An outstanding biological question is why tissue regeneration in mammals is limited, whereas urodele amphibians and teleost fish regenerate major structures, largely by cell cycle reentry. Upon inactivation of Rb, prolif...
- Mouse Germ Line Stem Cells Undergo Rapid and Stochastic Turnover
[作者：Klein, AM; Nakagawa, T; Ichikawa, R; Yoshida, S; Simons, BD,期刊：Cell Stem Cell, 页码：214-224 , 文章类型： Article，,卷期：2010年7-2]
- In cycling tissues, adult stem cells may be lost and subsequently replaced to ensure homeostasis. To examine the frequency of stem cell replacement, we analyzed the population dynamics of labeled stem cells in steady-sta...
- Molecular Pathway and Cell State Responsible for Dissociation-Induced Apoptosis in Human Pluripotent Stem Cells
[作者：Ohgushi, M; Matsumura, M; Eiraku, M; Murakami, K; Aramaki, T; Nishiyama, A; Muguruma, K; Nakano, T; Suga, H; Ueno, M; Ishizaki, T; Suemori, H; Narumiya, S; Niwa, H; Sasai, Y,期刊：Cell Stem Cell, 页码：225-239 , 文章类型： Article，,卷期：2010年7-2]
Human embryonic stem cells (hESCs), unlike mouse ones (mESCs), are vulnerable to apoptosis upon dissociation. Here, we show that the apoptosis, which is of a nonanoikis type, is caused by ROCK-dependent hyperactivatio...
- Actin-Myosin Contractility Is Responsible for the Reduced Viability of Dissociated Human Embryonic Stem Cells
[作者：Chen, GK; Hou, ZG; Gulbranson, DR; Thomson, JA,期刊：Cell Stem Cell, 页码：240-248 , 文章类型： Article，,卷期：2010年7-2]
- Human ESCs are the pluripotent precursor of the three embryonic germ layers. Human ESCs exhibit basal-apical polarity, junctional complexes, integrin-dependent matrix adhesion, and E-cadherin-dependent cell-cell adhesion...
- Chromatin Structure and Gene Expression Programs of Human Embryonic and Induced Pluripotent Stem Cells
[作者：Guenther, MG; Frampton, GM; Soldner, F; Hockemeyer, D; Mitalipova, M; Jaenisch, R; Young, RA,期刊：Cell Stem Cell, 页码：249-257 , 文章类型： Article，,卷期：2010年7-2]
- Knowledge of both the global chromatin structure and the gene expression programs of human embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs) should provide a robust means to assess whether the genome...
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