- Ephrinb3 induces mesostriatal dopaminergic projection to the striatum
[作者:Sun, JH; Gao, Q; Zhang, J; Bao, LH; Dong, HM; Liang, N; Li, GB; Li, ZH; Gao, YM,期刊:Biochemical and Biophysical Research Communications, 页码:194-199 , 文章类型: Article,,卷期:2010年400-2]
- Dopaminergic neurons in midbrain are subdivided into three subsets, forming mesostriatal, mesocortical and mesolimbic projections, respectively. The molecular mechanism specifying mesostriatal projection, which is import...
- An in vitro reconstitution system for the assessment of chromatin protein fluidity during Xenopus development
[作者:Aoki, R; Inui, M; Hayashi, Y; Sedohara, A; Okabayashi, K; Ohnuma, K; Murata, M; Asashima, M,期刊:Biochemical and Biophysical Research Communications, 页码:200-206 , 文章类型: Article,,卷期:2010年400-2]
- Chromatin fluidity, which is one of the indicators of higher-order structures in chromatin, is associated with cell differentiation. However, little is known about the relationships between chromatin fluidity and cell di...
- Aldehyde dehydrogenase 1A3 is transcriptionally activated by all-trans-retinoic acid in human epidermal keratinocytes
[作者:Koenig, U; Amatschek, S; Mildner, M; Eckhart, L; Tschachler, E,期刊:Biochemical and Biophysical Research Communications, 页码:207-211 , 文章类型: Article,,卷期:2010年400-2]
- Retinoids are regulators of keratinocyte differentiation in the epidermis and important therapeutics in dermatology. The formation of the most active retinoid, all-trans-retinoic acid (RA) by oxidation of retinal is cata...
- Application of maximin correlation analysis to classifying protein environments for function prediction
[作者:Lee, T; Min, H; Kim, SJ; Yoon, S,期刊:Biochemical and Biophysical Research Communications, 页码:219-224 , 文章类型: Article,,卷期:2010年400-2]
- More and more protein structures are being discovered, but most of these still have little functional information. Based on the assumption that structural resemblance would lead to functional similarity, researchers comp...
- PI3K/Akt signaling is involved in the disruption of gap junctional communication caused by v-Src and TNF-alpha
[作者:Ito, S; Hyodo, T; Hasegawa, H; Yuan, H; Hamaguchi, M; Senga, T,期刊:Biochemical and Biophysical Research Communications, 页码:230-235 , 文章类型: Article,,卷期:2010年400-2]
- Gap junctional communication, which is mediated by the connexin protein family, is essential for the maintenance of normal tissue function and homeostasis. Loss of intercellular communication results in a failure to coor...
- microRNA-195 promotes apoptosis and suppresses tumorigenicity of human colorectal cancer cells
[作者:Liu, L; Chen, L; Xu, YX; Li, R; Du, XH,期刊:Biochemical and Biophysical Research Communications, 页码:236-240 , 文章类型: Article,,卷期:2010年400-2]
- Deregulated microRNAs and their roles in cancer development have attracted much attention. In the present study, we analyzed the roles of miR-195 in colorectal cancer pathogenesis, as its participation in some other type...
- Repin1 maybe involved in the regulation of cell size and glucose transport in adipocytes
[作者:Ruschke, K; Illes, M; Kern, M; Kloting, I; Fasshauer, M; Schon, MR; Kosacka, J; Fitzl, G; Kovacs, P; Stumvoll, M; Bluher, M; Kloting, N,期刊:Biochemical and Biophysical Research Communications, 页码:246-251 , 文章类型: Article,,卷期:2010年400-2]
- Replication initiator 1 (Repin1) is highly expressed in liver and adipose tissue and has been suggested as candidate gene for obesity and its related metabolic disorders in congenic and subcongenic rat strains. The cellu...
- Tyrosine kinase 2 interacts with the proapoptotic protein Siva-1 and augments its apoptotic functions
[作者:Shimoda, HK; Shide, K; Kameda, T; Matsunaga, T; Shimoda, K,期刊:Biochemical and Biophysical Research Communications, 页码:252-257 , 文章类型: Article,,卷期:2010年400-2]
- Siva-1 is a molecule that has the potential to induce both extrinsic (receptor-mediated) and intrinsic (non-receptor-mediated) apoptosis. Siva-1 binds to CD27, a member of the tumor necrosis factor receptor (TNFR) family...
- Identification of BCAP-(L) as a negative regulator of the TLR signaling-induced production of IL-6 and IL-10 in macrophages by tyrosine phosphoproteomics
[作者:Matsumura, T; Oyama, M; Kozuka-Hata, H; Ishikawa, K; Inoue, T; Muta, T; Semba, K; Inoue, J,期刊:Biochemical and Biophysical Research Communications, 页码:265-270 , 文章类型: Article,,卷期:2010年400-2]
- Toll-like receptor (TLR) signaling in macrophages is essential for anti-pathogen responses such as cytokine production and antigen presentation. Although numerous reports suggest that protein tyrosine kinases (PTKs) are ...
- Hepatocyte Growth Factor stimulated cell scattering requires ERK and Cdc42-dependent tight junction disassembly
[作者:Togawa, A; Sfakianos, J; Ishibe, S; Suzuki, S; Fujigaki, Y; Kitagawa, M; Mellman, I; Cantley, LG,期刊:Biochemical and Biophysical Research Communications, 页码:271-277 , 文章类型: Article,,卷期:2010年400-2]
- The mechanism by which Hepatocyte Growth Factor (HGF) induces tight junction disassembly prior to cell scattering is largely unknown. Here, we show that HGF stimulates rapid loss of the TJ assembly protein Par6 from the ...
- Epigenetic regulation of neonatal cardiomyocytes differentiation
[作者:Kou, CYC; Lau, SLY; Au, KW; Leung, PY; Chim, SSC; Fung, KP; Waye, MMY; Tsui, SKW,期刊:Biochemical and Biophysical Research Communications, 页码:278-283 , 文章类型: Article,,卷期:2010年400-2]
- The relationship between DNA methylation, histone modifications and terminal differentiation in cardiomyocytes was investigated in this study. The upregulation of methylation-related proteins, including DNA methyltransfe...
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