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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共20条记录   Rab5 modulates aggregation and toxicity of mutant huntingtin through macroautophagy in cell and fly models of Huntington disease [作者：Ravikumar, B; Imarisio, S; Sarkar, S; O'Kane, CJ; Rubinsztein, DC,期刊：Journal of cell science, 页码：1649-1660 , 文章类型： Article，,卷期：2008年121-10] Huntington disease (HD) is caused by a polyglutamine-expansion mutation in huntingtin (HTT) that makes the protein toxic and aggregate-prone. The subcellular localisation of huntingtin and many of its interactors suggest... PAI1 stimulates assembly of the fibronectin matrix in osteosarcoma cells through crosstalk between the alpha v beta 5 and alpha 5 beta 1 integrins [作者：Vial, D; McKeown-Longo, PJ,期刊：Journal of cell science, 页码：1661-1670 , 文章类型： Article，,卷期：2008年121-10] The plasminogen activation system regulates matrix remodeling through both proteolytic and non-proteolytic mechanisms. Studies were undertaken to determine the effects of the plasminogen activator inhibitor 1 (PAI1) on t... Haemocyte-derived SPARC is required for collagen-IV-dependent stability of basal laminae in Drosophila embryos [作者：Martinek, N; Shahab, J; Saathoff, M; Ringuette, M,期刊：Journal of cell science, 页码：1671-1680 , 文章类型： Article，,卷期：2008年121-10] SPARC is an evolutionarily conserved collagen-binding extracellular matrix (ECM) glycoprotein whose morphogenetic contribution(s) to embryonic development remain elusive despite decades of research. We have therefore use... Isoform B of myosin II heavy chain mediates actomyosin contractility during TNF alpha-induced apoptosis [作者：Solinet, S; Vitale, ML,期刊：Journal of cell science, 页码：1681-1692 , 文章类型： Article，,卷期：2008年121-10] Cells that are treated long-term with TNF alpha or short-term with TGF alpha together with cycloheximide (CHX) undergo apoptosis. Cell shrinkage and detachment during apoptosis is dependent on actomyosin contractility. M... Interaction between the Drosophila heterochromatin proteins SUUR and HP1 [作者：Pindyurin, AV; Boldyreva, LV; Shloma, VV; Kolesnikova, TD; Pokholkova, GV; Andreyeva, EN; Kozhevnikova, EN; Ivanoschuk, IG; Zarutskaya, EA; Demakov, SA; Gorchakov, AA; Belyaeva, ES; Zhimulev, IF,期刊：Journal of cell science, 页码：1693-1703 , 文章类型： Article，,卷期：2008年121-10] SUUR (Suppressor of Under-Replication) protein is responsible for late replication and, as a consequence, for DNA underreplication of intercalary and pericentric heterochromatin in Drosophila melanogaster polytene chromo... In vivo role of lipid adducts on Wingless [作者：Franch-Marro, X; Wendler, F; Griffith, J; Maurice, MM; Vincent, JP,期刊：Journal of cell science, 页码：1587-1592 , 文章类型： Article，,卷期：2008年121-10] Two lipids (palmitate and palmitoleic acid) are appended onto Wnt proteins. It has been suggested that palmitate is required for signalling, whereas palmitoleic acid is necessary for progression through the secretory pat... A single point mutation in the LN domain of LAMA2 causes muscular dystrophy and peripheral amyelination [作者：Patton, BL; Wang, B; Tarumi, YS; Seburn, KL; Burgess, RW,期刊：Journal of cell science, 页码：1593-1604 , 文章类型： Article，,卷期：2008年121-10] Mutations in the gene encoding the basal lamina (BL) component laminin alpha 2 (LAMA2) cause merosin-deficient congenital muscular dystrophy 1A (MDC1A), a complex disorder that includes hypomyelination and myodegeneratio... Drosophila melanogaster kl-3 and kl-5 Y-loops harbor triple-stranded nucleic acids [作者：Piergentili, R; Mencarelli, C,期刊：Journal of cell science, 页码：1605-1612 , 文章类型： Article，,卷期：2008年121-10] Primary spermatocyte nuclei of Drosophila melanogaster contain three prominent lampbrush-like loops. The development of these structures has been associated with the transcription of three fertility factors located on th... Zfp64 participates in Notch signaling and regulates differentiation in mesenchymal cells [作者：Sakamoto, K; Tamamura, Y; Katsube, KI; Yamaguchi, A,期刊：Journal of cell science, 页码：1613-1623 , 文章类型： Article，,卷期：2008年121-10] Notch signaling is required for multiple aspects of tissue and cell differentiation. In this study, we identified zinc finger protein 64 (Zfp64) as a novel coactivator of Notch1. Zfp64 is associated with the intracellula... A verapamil-sensitive chloroquine-associated H+ leak from the digestive vacuole in chloroquine-resistant malaria parasites [作者：Lehane, AM; Hayward, R; Saliba, KJ; Kirk, K,期刊：Journal of cell science, 页码：1624-1632 , 文章类型： Article，,卷期：2008年121-10] Chloroquine resistance in the malaria parasite Plasmodium falciparum has made malaria increasingly difficult to control. Chloroquine-resistant parasites accumulate less chloroquine than their chloroquine-sensitive counte... Dnm1p-dependent peroxisome fission requires Caf4p, Mdv1p and Fis1p [作者：Motley, AM; Ward, GP; Hettema, EH,期刊：Journal of cell science, 页码：1633-1640 , 文章类型： Article，,卷期：2008年121-10] Yeast peroxisomes multiply by fission. Fission requires two dynamin-related proteins, Dnm1p and Vps1p. Using an in vivo fission assay, we show that Dnm1p-dependent peroxisome fission requires Fis1p, Caf4p and Mdv1p. Fluo... Analysis of Fyn function in hemostasis and alpha IIb beta 3-integrin signaling [作者：Reddy, KB; Smith, DM; Plow, EF,期刊：Journal of cell science, 页码：1641-1648 , 文章类型： Article，,卷期：2008年121-10] Recent studies have shown that Src-family kinases (SFKs) play an important role in mediating integrin signalling, and the beta 3 subunit of alpha IIb beta 3 integrin has been shown to interact with multiple SFK members. ... EML3 is a nuclear microtubule-binding protein required for the correct alignment of chromosomes in metaphase [作者：Tegha-Dunghu, J; Neumann, B; Reber, S; Krause, R; Erfle, H; Walter, T; Held, M; Rogers, P; Hupfeld, K; Ruppert, T; Ellenberg, J; Gruss, OJ,期刊：Journal of cell science, 页码：1718-1726 , 文章类型： Article，,卷期：2008年121-10] Assembly of the mitotic spindle requires a global change in the activity and constitution of the microtubule-binding-protein array at mitotic onset. An important subset of mitotic microtubule-binding proteins localises t... Ubiquitin-independent binding of Hrs mediates endosomal sorting of the interleukin-2 receptor beta-chain [作者：Yamashita, Y; Kojima, K; Tsukahara, T; Agawa, H; Yamada, K; Amano, Y; Kurotori, N; Tanaka, N; Sugamura, K; Takeshita, T,期刊：Journal of cell science, 页码：1727-1738 , 文章类型： Article，,卷期：2008年121-10] Several lines of evidence have revealed that ubiquitylation of membrane proteins serves as a signal for endosomal sorting into lysosomes or lytic vacuoles. The hepatocyte growth factor-regulated tyrosine kinase substrate... BNIP2 extra long inhibits RhoA and cellular transformation by Lbc RhoGEF via its BCH domain [作者：Soh, UJK; Low, BC,期刊：Journal of cell science, 页码：1739-1749 , 文章类型： Article，,卷期：2008年121-10] Increased expression of BCH-motif-containing molecule at the C-terminal region 1 (BMCC1) correlates with a favourable prognosis in neuroblastoma, but the underlying mechanism remains unknown. We here isolated BNIPXL (BNI... A spatially restricted increase in receptor mobility is involved in directional sensing during Dictyostelium discoideum chemotaxis [作者：de Keijzer, S; Serge, A; van Hemert, F; Lommerse, PHM; Lamers, GEM; Spaink, HP; Schmidt, T; Snaar-Jagalska, BE,期刊：Journal of cell science, 页码：1750-1757 , 文章类型： Article，,卷期：2008年121-10] The directed cell migration towards a chemotactic source, chemotaxis, involves three complex and interrelated processes: directional sensing, cell polarization and motility. Directional sensing allows migrating eukaryoti...