- Arabidopsis SPIRAL2 promotes uninterrupted microtubule growth by suppressing the pause state of microtubule dynamics
[作者:Yao, M; Wakamatsu, Y; Itoh, TJ; Shoji, T; Hashimoto, T,期刊:Journal of cell science, 页码:2372-2381 , 文章类型: Article,,卷期:2008年121-14]
- SPIRAL2 (SPR2) of Arabidopsis thaliana is a microtubule-associated protein containing multiple HEAT repeats that are found only in the plant lineage. We show that SPR2 and SP2L, their closest Arabidopsis homolog, are exp...
- eIF3k regulates apoptosis in epithelial cells by releasing caspase 3 from keratin-containing inclusions
[作者:Lin, YM; Chen, YR; Lin, JR; Wang, WJ; Inoko, A; Inagaki, M; Wu, YC; Chen, RH,期刊:Journal of cell science, 页码:2382-2393 , 文章类型: Article,,卷期:2008年121-14]
- Keratins 8 and 18 (collectively referred to as K8/K18) are the major components of intermediate filaments of simple epithelial cells. Recent studies have revealed the function of K8/K18 in apoptosis modulation. Here, we ...
- Phosphorylation of AFAP-110 affects podosome lifespan in A7r5 cells
[作者:Dorfleutner, A; Cho, Y; Vincent, D; Cunnick, J; Lin, H; Weed, SA; Stehlik, C; Flynn, DC,期刊:Journal of cell science, 页码:2394-2405 , 文章类型: Article,,卷期:2008年121-14]
- AFAP-110 is an actin-binding and-crosslinking protein that is enriched in Src and phorbol ester (PE)-induced podosomes. In vascular smooth muscle cells endogenous AFAP-110 localized to actin stress fibers and, in respons...
- In migrating cells, the Golgi complex and the position of the centrosome depend on geometrical constraints of the substratum
[作者:Pouthas, F; Girard, P; Lecaudey, V; Ly, TBN; Gilmour, D; Boulin, C; Pepperkok, R; Reynaud, EG,期刊:Journal of cell science, 页码:2406-2414 , 文章类型: Article,,卷期:2008年121-14]
- Although cells migrate in a constrained 3D environment in vivo, in-vitro studies have mainly focused on the analysis of cells moving on 2D substrates. Under such conditions, the Golgi complex is always located towards th...
- Exceptional mechanical and structural stability of HSV-1 unveiled with fluid atomic force microscopy
[作者:Liashkovich, I; Hafezi, W; Kuhn, JE; Oberleithner, H; Kramer, A; Shahin, V,期刊:Journal of cell science, 页码:2287-2292 , 文章类型: Article,,卷期:2008年121-14]
- Evidence is emerging that changes in the structural and mechanical properties of viral particles are closely linked and that such changes are essential to infectivity. Here, applying the nanostructural and nanomechanical...
- A novel small-molecule inhibitor reveals a possible role of kinesin-5 in anastral spindle-pole assembly
[作者:Groen, AC; Needleman, D; Brangwynne, C; Gradinaru, C; Fowler, B; Mazitschek, R; Mitchison, TJ,期刊:Journal of cell science, 页码:2293-2300 , 文章类型: Article,,卷期:2008年121-14]
- The tetrameric plus-end-directed motor, kinesin-5, is essential for bipolar spindle assembly. Small-molecule inhibitors of kinesin-5 have been important tools for investigating its function, and some are currently under ...
- Lipid droplets are arrested in the ER membrane by tight binding of lipidated apolipoprotein B-100
[作者:Ohsaki, Y; Cheng, JL; Suzuki, M; Fujita, A; Fujimoto, T,期刊:Journal of cell science, 页码:2415-2422 , 文章类型: Article,,卷期:2008年121-14]
- Apolipoprotein B-100 (ApoB) is a major component of very-lowdensity lipoproteins, and is deposited in a region around lipid droplets (LDs) called the ApoB- crescent'. The ApoB-crescent is thought to be related to ApoB de...
- TRPC6 channels promote dendritic growth via the CaMKIV-CREB pathway
[作者:Tai, YL; Feng, SJ; Ge, RL; Du, WL; Zhang, XX; He, ZH; Wang, YZ,期刊:Journal of cell science, 页码:2301-2307 , 文章类型: Article,,卷期:2008年121-14]
- The canonical transient receptor potential channels (TRPCs) are Ca2+-permeable nonselective cation channels with various physiological functions. Here, we report that TRPC6, a member of the TRPC family, promotes hippocam...
- Initiation and execution of lipotoxic ER stress in pancreatic beta-cells
[作者:Cunha, DA; Hekerman, P; Ladriere, L; Bazarra-Castro, A; Ortis, F; Wakeham, MC; Moore, F; Rasschaert, J; Cardozo, AK; Bellomo, E; Overbergh, L; Mathieu, C; Lupi, R; Hai, T; Herchuelz, A; Marchetti, P; Rutter, GA; Eizirik, DL; Cnop, M,期刊:Journal of cell science, 页码:2308-2318 , 文章类型: Review,,卷期:2008年121-14]
- Free fatty acids (FFA) cause apoptosis of pancreatic beta-cells and might contribute to beta-cell loss in type 2 diabetes via the induction of endoplasmic reticulum (ER) stress. We studied here the molecular mechanisms i...
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