- Progression of meiotic recombination requires structural maturation of the central element of the synaptonemal complex
[作者:Hamer, G; Wang, H; Bolcun-Filas, E; Cooke, HJ; Benavente, R; Hoog, C,期刊:Journal of cell science, 页码:2445-2451 , 文章类型: Article,,卷期:2008年121-15]
- The synaptonemal complex is an elaborate meiosis-specific supramolecular protein assembly that promotes chromosome synapsis and meiotic recombination. We inactivated the meiosis-specific gene Tex12 and found that TEX12 i...
- The secreted Dictyostelium protein CfaD is a chalone
[作者:Bakthavatsalam, D; Brock, DA; Nikravan, NN; Houston, KD; Hatton, RD; Gomer, RH,期刊:Journal of cell science, 页码:2473-2480 , 文章类型: Article,,卷期:2008年121-15]
- Dictyostelium discoideum cells secrete CfaD, a protein that is similar to cathepsin proteases. Cells that lack cfaD proliferate faster and reach a higher stationary-phase density than wildtype cells, whereas cells that o...
- An AR-Skp2 pathway for proliferation of androgen-dependent prostate-cancer cells
[作者:Wang, HB; Sun, DQ; Ji, P; Mohler, J; Zhu, L,期刊:Journal of cell science, 页码:2578-2587 , 文章类型: Article,,卷期:2008年121-15]
- Androgen-androgen-receptor ( androgen-AR) signaling in normal prostate epithelium promotes terminal luminal epithelial cell differentiation. In androgen-dependent prostate-cancer cells, androgen-AR signaling gains the ab...
- Characterization of the mitochondrial protein LETM1, which maintains the mitochondrial tubular shapes and interacts with the AAA-ATPase BCS1L
[作者:Tamai, S; Iida, H; Yokota, S; Sayano, T; Kiguchiya, S; Ishihara, N; Hayashi, JI; Mihara, K; Oka, T,期刊:Journal of cell science, 页码:2588-2600 , 文章类型: Article,,卷期:2008年121-15]
- LETM1 is located in the chromosomal region that is deleted in patients suffering Wolf-Hirschhorn syndrome; it encodes a homolog of the yeast protein Mdm38 that is involved in mitochondrial morphology. Here, we describe t...
- Regulation of Kalirin by Cdk5
[作者:Xin, X; Wang, Y; Ma, XM; Rompolas, P; Keutmann, HT; Mains, RE; Eipper, BA,期刊:Journal of cell science, 页码:2601-2611 , 文章类型: Article,,卷期:2008年121-15]
- Kalirin, one of the few Rho guanine nucleotide exchange factors ( GEFs) that contains spectrin-like repeats, plays a critical role in axon extension and maintenance of dendritic spines. PC12 cells were used to determine ...
- Identification of two partners from the bacterial Kef exchanger family for the apical plasma membrane V-ATPase of Metazoa
[作者:Day, JP; Wan, S; Allan, AK; Kean, L; Davies, SA; Gray, JV; Dow, JAT,期刊:Journal of cell science, 页码:2612-2619 , 文章类型: Article,,卷期:2008年121-15]
- The vital task of vectorial solute transport is often energised by a plasma membrane, proton-motive V-ATPase. However, its proposed partner, an apical alkali-metal/proton exchanger, has remained elusive. Here, both FlyAt...
- Divergent polarization mechanisms during vertebrate epithelial development mediated by the Crumbs complex protein Nagie oko
[作者:Bit-Avragim, N; Hellwig, N; Rudolph, F; Munson, C; Stainier, DYS; Abdelilah-Seyfried, S,期刊:Journal of cell science, 页码:2503-2510 , 文章类型: Article,,卷期:2008年121-15]
- The zebrafish MAGUK protein Nagie oko is a member of the evolutionarily conserved Crumbs protein complex and functions as a scaffolding protein involved in the stabilization of multiprotein assemblies at the tight juncti...
- Paxillin comes of age
[作者:Deakin, NO; Turner, CE,期刊:Journal of cell science, 页码:2435-2444 , 文章类型: Review,,卷期:2008年121-15]
- Paxillin is a multi-domain scaffold protein that localizes to the intracellular surface of sites of cell adhesion to the extracellular matrix. Through the interactions of its multiple protein-binding modules, many of whi...
- Ca2+ oscillation frequency regulates agonist-stimulated gene expression in vascular endothelial cells
[作者:Zhu, LP; Luo, YG; Chen, TX; Chen, FR; Wang, T; Hu, Q,期刊:Journal of cell science, 页码:2511-2518 , 文章类型: Article,,卷期:2008年121-15]
- A physiological membrane-receptor agonist typically stimulates oscillations, of varying frequencies, in cytosolic Ca2+ concentration ([ Ca2+](i)). Whether and how [ Ca2+](i) oscillation frequency regulates agonist-stimul...
- EGF induces coalescence of different lipid rafts
[作者:Hofman, EG; Ruonala, MO; Bader, AN; van den Heuvel, D; Voortman, J; Roovers, RC; Verkleij, AJ; Gerritsen, HC; Henegouwen, PMPV,期刊:Journal of cell science, 页码:2519-2528 , 文章类型: Article,,卷期:2008年121-15]
- The suggestion that microdomains may function as signaling platforms arose from the presence of growth factor receptors, such as the EGFR, in biochemically isolated lipid raft fractions. To investigate the role of EGFR a...
- Slk19-dependent mid-anaphase pause in kinesin-5-mutated cells
[作者:Movshovich, N; Fridman, V; Gerson-Gurwitz, A; Shumacher, I; Gertsberg, I; Fich, A; Hoyt, MA; Katz, B; Gheber, L,期刊:Journal of cell science, 页码:2529-2539 , 文章类型: Article,,卷期:2008年121-15]
- We examined spindle elongation in anaphase in Saccharomyces cerevisiae cells mutated for the kinesin-5 motor proteins Cin8 and Kip1. Cells were deleted for KIP1 and/ or expressed one of two motor-domain Cin8 mutants ( Ci...
- Live cell imaging and electron microscopy reveal dynamic processes of BAF-directed nuclear envelope assembly
[作者:Haraguchi, T; Kojidani, T; Koujin, T; Shimi, T; Osakada, H; Mori, C; Yamamoto, A; Hiraoka, Y,期刊:Journal of cell science, 页码:2540-2554 , 文章类型: Article,,卷期:2008年121-15]
- Assembly of the nuclear envelope ( NE) in telophase is essential for higher eukaryotic cells to re-establish a functional nucleus. Time-lapse, FRAP and FRET analyses in human cells showed that barrier-to-autointegration ...
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