- The regulated exocytosis of enlargeosomes is mediated by a SNARE machinery that includes VAMP4
[作者:Cocucci, E; Racchetti, G; Rupnik, M; Meldolesi, J,期刊:Journal of cell science, 页码:2983-2991 , 文章类型: Article,,卷期:2008年121-18]
- The mechanisms governing the fast, regulated exocytosis of enlargeosomes have been unknown, except for the participation of annexin-2 in a pre-fusion step. We investigated whether any SNAREs are involved. In PC12-27 cell...
- HIF1 transcription factor regulates laminin-332 expression and keratinocyte migration
[作者:Fitsialos, G; Bourget, I; Augier, S; Ginouves, A; Rezzonico, R; Odorisio, T; Cianfarani, F; Virolle, T; Pouyssegur, J; Meneguzzi, G; Berra, E; Ponzio, G; Busca, R,期刊:Journal of cell science, 页码:2992-3001 , 文章类型: Article,,卷期:2008年121-18]
- Epidermal wound repair is a complex process involving the fine orchestrated regulation of crucial cell functions, such as proliferation, adhesion and migration. Using an in vitro model that recapitulates central aspects ...
- Heat shock causes a decrease in polysomes and the appearance of stress granules in trypanosomes independently of eIF2 alpha phosphorylation at Thr169
[作者:Kramer, S; Queiroz, R; Ellis, L; Webb, H; Hoheisel, JD; Clayton, C; Carrington, M,期刊:Journal of cell science, 页码:3002-3014 , 文章类型: Article,,卷期:2008年121-18]
- In trypanosomes there is an almost total reliance on post-transcriptional mechanisms to alter gene expression; here, heat shock was used to investigate the response to an environmental signal. Heat shock rapidly and reve...
- Efficient coupling of Sec23-Sec24 to Sec13-Sec31 drives COPII-dependent collagen secretion and is essential for normal craniofacial development
[作者:Townley, AK; Feng, Y; Schmidt, K; Carter, DA; Porter, R; Verkade, P; Stephens, DJ,期刊:Journal of cell science, 页码:3025-3034 , 文章类型: Article,,卷期:2008年121-18]
- The COPII coat assembles on endoplasmic reticulum membranes to coordinate the collection of secretory cargo with the formation of transport vesicles. During COPII assembly, Sar1 deforms the membrane and recruits the Sec2...
- Synapsin-I- and synapsin-II-null mice display an increased age-dependent cognitive impairment
[作者:Corradi, A; Zanardi, A; Giacomini, C; Onofri, F; Valtorta, F; Zoli, M; Benfenati, F,期刊:Journal of cell science, 页码:3042-3051 , 文章类型: Article,,卷期:2008年121-18]
- Synapsin I (SynI) and synapsin II (SynII) are major synaptic vesicle (SV) proteins that function in the regulation of the availability of SVs for release in mature neurons. SynI and SynII show a high level of sequence si...
- Centrin4 coordinates cell and nuclear division in T-brucei
[作者:Shi, J; Franklin, JB; Yelinek, JT; Ebersberger, I; Warren, G; He, CY,期刊:Journal of cell science, 页码:3062-3070 , 文章类型: Article,,卷期:2008年121-18]
- Centrins are Ca2+-binding proteins that have been implicated in a number of biological processes, including organelle duplication, mRNA export, DNA repair and signal transduction. In the protozoan parasite Trypanosoma br...
- Chondroitin-4-sulfation negatively regulates axonal guidance and growth
[作者:Wang, H; Katagiri, Y; McCann, TE; Unsworth, E; Goldsmith, P; Yu, ZX; Tan, F; Santiago, L; Mills, EM; Wang, Y; Symes, AJ; Geller, HM,期刊:Journal of cell science, 页码:3083-3091 , 文章类型: Article,,卷期:2008年121-18]
- Glycosaminoglycan (GAG) side chains endow extracellular matrix proteoglycans with diversity and complexity based upon the length, composition and charge distribution of the polysaccharide chain. Using cultured primary ne...
- The GDP-dependent Rab27a effector coronin 3 controls endocytosis of secretory membrane in insulin-secreting cell lines
[作者:Kimura, T; Kaneko, Y; Yamada, S; Ishihara, H; Senda, T; Iwamatsu, A; Niki, I,期刊:Journal of cell science, 页码:3092-3098 , 文章类型: Article,,卷期:2008年121-18]
- Rab27a is involved in the control of membrane traffic, a crucial step in the regulated secretion. Typically, the guanosine triphosphate (GTP)-bound form has been considered to be active and, therefore, searching for prot...
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