- Sprouty-2 controls c-Met expression and metastatic potential of colon cancer cells: sprouty/c-Met upregulation in human colonic adenocarcinomas
[作者:Holgren, C; Dougherty, U; Edwin, F; Cerasi, D; Taylor, I; Fichera, A; Joseph, L; Bissonnette, M; Khare, S,期刊:Oncogene, 页码:5241-5253 , 文章类型: Article,,卷期:2010年29-38]
- Sprouty negatively regulates receptor tyrosine kinase signals by inhibiting Ras/extracellular signal-regulated kinase (ERK) pathways. Sprouty is downregulated in breast, prostate and liver cancers and appears to function...
- An anti-Axl monoclonal antibody attenuates xenograft tumor growth and enhances the effect of multiple anticancer therapies
[作者:Ye, X; Li, Y; Stawicki, S; Couto, S; Eastham-Anderson, J; Kallop, D; Weimer, R; Wu, Y; Pei, L,期刊:Oncogene, 页码:5254-5264 , 文章类型: Article,,卷期:2010年29-38]
- Axl is expressed in various types of cancer and is involved in multiple processes of tumorigenesis, including promoting tumor cell growth, migration, invasion, metastasis as well as angiogenesis. To evaluate further the ...
- The stromal gene encoding the CD274 antigen as a genetic modifier controlling survival of mice with gamma-radiation-induced T-cell lymphoblastic lymphomas
[作者:Santos, J; Gonzalez-Sanchez, L; Villa-Morales, M; Ors, I; Lopez-Nieva, P; Vaquero, C; Gonzalez-Gugel, E; Fernandez-Navarro, P; Roncero, AM; Guenet, JL; Montagutelli, X; Fernandez-Piqueras, J,期刊:Oncogene, 页码:5265-5273 , 文章类型: Article,,卷期:2010年29-38]
- Using an inter-specific subcongenic strain, Nested Recombinant Haplotype 3 (NRH3), generated between two mouse strains showing extreme differences in gamma-radiation-induced thymic lymphoma susceptibility (SEG/Pas and C5...
- Cell delivery of Met docking site peptides inhibit angiogenesis and vascular tumor growth
[作者:Cantelmo, AR; Cammarota, R; Noonan, DM; Focaccetti, C; Comoglio, PM; Prat, M; Albini, A,期刊:Oncogene, 页码:5286-5298 , 文章类型: Article,,卷期:2010年29-38]
- Hepatocyte growth factor (HGF) and its receptor Met are responsible for a wide variety of cellular responses, both physiologically during embryo development and tissue homeostasis, and pathologically, particularly during...
- HMGB1 release and redox regulates autophagy and apoptosis in cancer cells
[作者:Tang, D; Kang, R; Cheh, CW; Livesey, KM; Liang, X; Schapiro, NE; Benschop, R; Sparvero, LJ; Amoscato, AA; Tracey, KJ; Zeh, HJ; Lotze, MT,期刊:Oncogene, 页码:5299-5310 , 文章类型: Article,,卷期:2010年29-38]
- The functional relationship and cross-regulation between autophagy and apoptosis is complex. In this study we show that the high-mobility group box 1 protein (HMGB1) is a redox-sensitive regulator of the balance between ...
- The cell polarity regulator hScrib controls ERK activation through a KIM site-dependent interaction
[作者:Nagasaka, K; Pim, D; Massimi, P; Thomas, M; Tomaic, V; Subbaiah, VK; Kranjec, C; Nakagawa, S; Yano, T; Taketani, Y; Myers, M; Banks, L,期刊:Oncogene, 页码:5311-5321 , 文章类型: Article,,卷期:2010年29-38]
- The cell polarity regulator, human Scribble (hScrib), is a potential tumour suppressor whose loss is a frequent event in late-stage cancer development. Little is yet known about the mode of action of hScrib, although rec...
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