- LAPTM4B: A novel cancer-associated gene motivates multidrug resistance through efflux and activating PI3K/AKT signaling
[作者：Li, L; Wei, XH; Pan, YP; Li, HC; Yang, H; He, QH; Pang, Y; Shan, Y; Xiong, FX; Shao, GZ; Zhou, RL,期刊：Oncogene, 页码：5785-5795 , 文章类型： Article，,卷期：2010年29-43]
- LAPTM4B (lysosomal protein transmembrane 4 beta) is a newly identified cancer-associated gene. Both of its mRNA and the encoded LAPTM4B-35 protein are significantly upregulated with more than 70% frequency in a wide vari...
- A previously unrecognized promoter of LMO2 forms part of a transcriptional regulatory circuit mediating LMO2 expression in a subset of T-acute lymphoblastic leukaemia patients
[作者：Oram, SH; Thoms, JAI; Pridans, C; Janes, ME; Kinston, SJ; Anand, S; Landry, JR; Lock, RB; Jayaraman, PS; Huntly, BJ; Pimanda, JE; Gottgens, B,期刊：Oncogene, 页码：5796-5808 , 文章类型： Article，,卷期：2010年29-43]
- The T-cell oncogene Lim-only 2 (LMO2) critically influences both normal and malignant haematopoiesis. LMO2 is not normally expressed in T cells, yet ectopic expression is seen in the majority of T-acute lymphoblastic leu...
- Somatic p16(INK4a) loss accelerates melanomagenesis
[作者：Monahan, KB; Rozenberg, GI; Krishnamurthy, J; Johnson, SM; Liu, W; Bradford, MK; Horner, J; DePinho, RA; Sharpless, NE,期刊：Oncogene, 页码：5809-5817 , 文章类型： Article，,卷期：2010年29-43]
- Loss of p16(INK4a)-RB and ARF-p53 tumor suppressor pathways, as well as activation of RAS-RAF signaling, is seen in a majority of human melanomas. Although heterozygous germline mutations of p16(INK4a) are associated wit...
- Id1 enhances RING1b E3 ubiquitin ligase activity through the Mel-18/Bmi-1 polycomb group complex
[作者：Qian, T; Lee, JY; Park, JH; Kim, HJ; Kong, G,期刊：Oncogene, 页码：5818-5827 , 文章类型： Article，,卷期：2010年29-43]
- The helix-loop-helix inhibitor of differentiation and DNA binding (Id1) is well known as an oncogene in various tumors. Although it has been reported that Id1 promotes several oncogenic processes, it is still unclear whe...
- Regulation of the NRSF/REST gene by methylation and CREB affects the cellular phenotype of small-cell lung cancer
[作者：Kreisler, A; Strissel, PL; Strick, R; Neumann, SB; Schumacher, U; Becker, CM,期刊：Oncogene, 页码：5828-5838 , 文章类型： Article，,卷期：2010年29-43]
- The neuron-restrictive silencer factor/RE1-silencing transcription factor (NRSF/REST) is a negative regulator of gene expression restricting the expression of neuronal genes to the nervous system. NRSF/REST is highly exp...
- A Rac-Pak signaling pathway is essential for ErbB2-mediated transformation of human breast epithelial cancer cells
[作者：Arias-Romero, LE; Villamar-Cruz, O; Pacheco, A; Kosoff, R; Huang, M; Muthuswamy, SK; Chernoff, J,期刊：Oncogene, 页码：5839-5849 , 文章类型： Article，,卷期：2010年29-43]
- The activation of receptor tyrosine kinases, particularly ErbB2, has an important role in the genesis of breast cancer. ErbB2 kinase activity promotes Ras-mediated stimulation of downstream protein kinase cascades, inclu...
- Characterization of Delta Np73 expression and regulation in gastric and esophageal tumors
[作者：Vilgelm, AE; Hong, SM; Washington, MK; Wei, J; Chen, H; El-Rifai, W; Zaika, A,期刊：Oncogene, 页码：5861-5868 , 文章类型： Article，,卷期：2010年29-43]
- p73 is a member of the p53 protein family. Although the tumor suppressor function of p53 is clearly defined, the role of p73 in tumorigenesis is still a matter of debate. A complex pattern of expression of p73 isoforms m...
- MicroRNA dysregulation in gastric cancer: a new player enters the game
[作者：Wu, WKK; Lee, CW; Cho, CH; Fan, D; Wu, K; Yu, J; Sung, JJY,期刊：Oncogene, 页码：5761-5771 , 文章类型： Review，,卷期：2010年29-43]
- Gastric carcinogenesis is a multistep process involving genetic and epigenetic alteration of protein-coding proto-oncogenes and tumor-suppressor genes. Recent discoveries have shed new light on the involvement of a class...
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