- A solid-in-oil nanodispersion for transcutaneous protein delivery
[作者:Tahara, Y; Honda, S; Kamiya, N; Piao, H; Hirata, A; Hayakawa, E; Fujii, T; Goto, M,期刊:Journal of controlled release, 页码:14-18 , 文章类型: Article,,卷期:2008年131-1]
- Transcutaneous delivery attracts much attention but remains a challenging strategy for hydrophilic macromolecular drug administration. In the present study, we demonstrated that a solid-in-oil (S/O) nanodispersion, an oi...
- Adhesion and ultrasound-induced delivery from monodisperse microbubbles in a parallel plate flow cell
[作者:Schmidt, BJ; Sousa, I; van Beek, AA; Bohmer, MR,期刊:Journal of controlled release, 页码:19-26 , 文章类型: Article,,卷期:2008年131-1]
- Microbubbles, ultrasound contrast agents currently in development as ultrasonically activated drug delivery vehicles, were studied using a novel flow cell design. The flow cell combined ultrasound compatibility, a planar...
- Identification of a peptide ligand recognizing dysfunctional endothelial cells for targeting atherosclerosis
[作者:Thapa, N; Hong, HY; Sangeetha, P; Kim, IS; Yoo, J; Rhee, K; Oh, GT; Kwon, IC; Lee, BH,期刊:Journal of controlled release, 页码:27-33 , 文章类型: Article,,卷期:2008年131-1]
- Targeting ligands to dysfunctional or activated endothelial cells overlying atherosclerotic plaques could provide tools for selective drug delivery to atherosclerotic lesions. To identify peptides selectively targeting d...
- Mechanism of controlled drug release from a salting-out taste-masking system
[作者:Yoshida, T; Tasaki, H; Maeda, A; Katsuma, M; Sako, K; Uchida, T,期刊:Journal of controlled release, 页码:47-53 , 文章类型: Article,,卷期:2008年131-1]
- A "salting-out taste-masking system" is a multiparticulate system consisting of a drug core, a salting-out layer containing salts and water-soluble polymers, and a water-penetration control layer containing water-insolub...
- Polyhydroxyethylaspartamide-spermine copolymers: Efficient vectors for gene delivery
[作者:Cavallcaro, G; Scire, S; Licciardi, M; Ogris, M; Wagner, E; Giammona, G,期刊:Journal of controlled release, 页码:54-63 , 文章类型: Article,,卷期:2008年131-1]
- Aim of this paper was that to prepare biocompatible, polyaspartamide based copolymers containing spermine or spermine/hydrophobic side chains able to condense nucleic acids and to transfect mammalian cells. Copolymers we...
- Effect of hepatocyte growth factor encapsulated in targeted liposomes on liver cirrhosis
[作者:Li, F; Sun, JY; Wang, JY; Du, SL; Lu, WY; Liu, M; Xie, C; Shi, JY,期刊:Journal of controlled release, 页码:77-82 , 文章类型: Article,,卷期:2008年131-1]
- Hepatocyte growth factor (HGF) was encapsulated into sterically stabilized liposomes (SSL) in order to protect it from in vivo degradation. Cyclic Arg-Gly-Asp (RGD) peptides were combined with maleimide-[poly (ethylene g...
- Dynamics of controlled release systems based on water-in-water emulsions: A general theory
[作者:Sagis, LMC,期刊:Journal of controlled release, 页码:5-13 , 文章类型: Review,,卷期:2008年131-1]
- Phase-separated biopolymer solutions, and aqueous dispersions of hydrogel beads, liposomes, polymersomes, aqueous polymer microcapsules, and colloidosomes are all examples of water-in-water emulsions. These systems can b...
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