- Structural modeling of RNase P RNA of the hyperthermophilic archaeon Pyrococcus horikoshii OT3
[作者:Zwieb, C; Nakao, Y; Nakashima, T; Takagi, H; Goda, S; Andersen, ES; Kakuta, Y; Kimura, M,期刊:Biochemical and Biophysical Research Communications, 页码:517-522 , 文章类型: Article,,卷期:2011年414-3]
- Ribonuclease P (RNase P) is a ubiquitous trans-acting ribozyme that processes the 5' leader sequence of precursor tRNA (pre-tRNA). The RNase P RNA (PhopRNA) of the hyperthermophilic archaeon Pyrococcus horikoshii OT3 is ...
- Ribosomal protein S3 is stabilized by sumoylation
[作者:Jang, CY; Shin, HS; Kim, HD; Kim, JW; Choi, SY; Kim, J,期刊:Biochemical and Biophysical Research Communications, 页码:523-527 , 文章类型: Article,,卷期:2011年414-3]
- Human ribosomal protein S3 (rpS3) acts as a DNA repair endonuclease. The multiple functions of this protein are regulated by post-translational modifications including phosphorylation and methylation. Using a yeast-two h...
- Mnl2, a novel component of the ER associated protein degradation pathway
[作者:Benitez, EM; Stolz, A; Becher, A; Wolf, DH,期刊:Biochemical and Biophysical Research Communications, 页码:528-532 , 文章类型: Article,,卷期:2011年414-3]
- In eukaryotes, membrane and soluble proteins of the secretory pathway enter the endoplasmic reticulum (ER) after synthesis in an unfolded state. Directly after entry, most proteins are modified with glycans at suitable g...
- Arsenite induces cell transformation by reactive oxygen species, AKT, ERK1/2, and p70S6K1
[作者:Carpenter, RL; Jiang, Y; Jing, Y; He, J; Rojanasakul, Y; Liu, LZ; Jiang, BH,期刊:Biochemical and Biophysical Research Communications, 页码:533-538 , 文章类型: Article,,卷期:2011年414-3]
- Arsenic is naturally occurring element that exists in both organic and inorganic formulations. The inorganic form arsenite has a positive association with development of multiple cancer types. There are significant popul...
- Role of lipid rafts in porcine reproductive and respiratory syndrome virus infection in MARC-145 cells
[作者:Huang, L; Zhang, YP; Yu, YL; Sun, MX; Li, C; Chen, PY; Mao, X,期刊:Biochemical and Biophysical Research Communications, 页码:545-550 , 文章类型: Article,,卷期:2011年414-3]
- Lipid rafts play an important role in the life cycle of many viruses. Cholesterol is a critical structural component of lipid rafts. Although the porcine reproductive and respiratory syndrome virus (PRRSV) has restricted...
- Cell death pathology: Perspective for human diseases
[作者:Agostini, M; Tucci, P; Melino, G,期刊:Biochemical and Biophysical Research Communications, 页码:451-455 , 文章类型: Review,,卷期:2011年414-3]
- Apoptosis, a genetically regulated form of cell death with distinct biochemical and morphological features, plays a relevant physiological and pathological role in the organism, being pivotal in the maintenance of tissue...
- Green tea polyphenol epigallocatechin-3-gallate suppresses melanoma growth by inhibiting inflammasome and IL-1 beta secretion
[作者:Ellis, LZ; Liu, WM; Luo, YC; Okamoto, M; Qu, D; Dunn, JH; Fujita, M,期刊:Biochemical and Biophysical Research Communications, 页码:551-556 , 文章类型: Article,,卷期:2011年414-3]
- Epigallocatechin-3-gallate (EGCG), the major polyphenolic component of green tea, has been demonstrated to possess anti-inflammatory, antioxidant, anti-mutagenic and anti-carcinogenic properties. The anti-melanoma effect...
- Vitamin D receptor controls expression of the anti-aging klotho gene in mouse and human renal cells
[作者:Forster, RE; Jurutka, PW; Hsieh, JC; Haussler, CA; Lowmiller, CL; Kaneko, I; Haussler, MR; Whitfield, GK,期刊:Biochemical and Biophysical Research Communications, 页码:557-562 , 文章类型: Article,,卷期:2011年414-3]
- Isoforms of the mammalian klotho protein serve as membrane co-receptors that regulate renal phosphate and calcium reabsorption. Phosphaturic effects of klotho are mediated in cooperation with fibroblast growth factor rec...
- The pan-ErbB receptor tyrosine kinase inhibitor canertinib promotes apoptosis of malignant melanoma in vitro and displays anti-tumor activity in vivo
[作者:Severinsson, EAD; Trinks, C; Green, H; Abdiu, A; Hallbeck, AL; Stal, O; Walz, TM,期刊:Biochemical and Biophysical Research Communications, 页码:563-568 , 文章类型: Article,,卷期:2011年414-3]
- The ErbB receptor family has been suggested to constitute a therapeutic target for tumor-specific treatment of malignant melanoma. Here we investigate the effect of the pan-ErbB tyrosine kinase inhibitor canertinib on ce...
- Role of the p21-activated kinases (PAKs) in influenza A virus replication
[作者:Pascua, PNQ; Lee, JH; Song, MS; Park, SJ; Baek, YH; Ann, BH; Shin, EY; Kim, EG; Choi, YK,期刊:Biochemical and Biophysical Research Communications, 页码:569-574 , 文章类型: Article,,卷期:2011年414-3]
- Influenza A virus infection stimulates a wide range of virus-supportive or antiviral mechanisms in host cells. p21-Activated kinase 1 (PAK1) is a serine/threonine kinase that regulates a number of fundamental cellular pr...
- Stimulation of the amino acid transporter SLC6A19 by JAK2
[作者:Bhavsar, SK; Hosseinzadeh, Z; Merches, K; Gu, SC; Broer, S; Lang, F,期刊:Biochemical and Biophysical Research Communications, 页码:456-461 , 文章类型: Article,,卷期:2011年414-3]
- JAK2 (Janus kinase-2) is expressed in a wide variety of cells including tumor cells and contributes to the proliferation and survival of those cells. The gain of function mutation (V617F)JAK2 mutant is found in the major...
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