- The Effect of Combined CJZ3, a Lomerizine Derivative, With Verapamil on P-glycoprotein Efflux Function In Vitro
[作者：Ji, BS; Ren, YL; He, L,期刊：Drug Development Research, 页码：305-309 , 文章类型： Article，,卷期：2011年72-4]
- In the effort to inhibit P-glycoprotein (P-gp) efflux function with greater activity and less side effect, the combined effect of pair CJZ3 and verapamil (Ver) was evaluated isobolographically in numerous fixed-ratio com...
- Varenicline Does Not Alter Brain Stimulation Reward Thresholds and Reverses Nicotine-Facilitated Thresholds in Rats
[作者：Vann, RE; Tobey, KM; Lobe, SL; Kipps, B; Kwilasz, AJ; Aceto, MD; Harris, LS,期刊：Drug Development Research, 页码：310-314 , 文章类型： Article，,卷期：2011年72-4]
- The partial alpha 4 beta 2 nicotinic acetylcholine receptor (nAChR) agonist, varenicline, shares some but not all preclinical effects of nicotine. This unique profile may be crucial to its effectiveness as a therapeutic ...
- Madecassoside Induces Apoptosis of Keloid Fibroblasts Via a Mitochondrial-Dependent Pathway
[作者：Song, J; Dai, Y; Bian, DF; Zhang, HF; Xu, XX; Xia, YF; Gong, ZN,期刊：Drug Development Research, 页码：315-322 , 文章类型： Article，,卷期：2011年72-4]
- Centella asiatica herb is a frequently prescribed drug in southeastern Asia and China that can simultaneously facilitate wound healing and prevent scar formation. The active constituents and underlying mechanisms respons...
- Effect of Capsazepine on [Ca(2+)](i) in MDCK Renal Tubular Cells
[作者：Tsai, JY; Kuo, CC; Chou, CT; Chao, D; Cheng, HH; Wang, JL; Cheng, JS; Lin, KL; Huang, JK; Chang, HT; Jan, CR,期刊：Drug Development Research, 页码：323-329 , 文章类型： Article，,卷期：2011年72-4]
- The current study explored whether capsazepine changed basal cytosolic free Ca(2+) concentrations ([Ca(2+)](i)) levels in suspended Madin Darby canine kidney (MDCK) cells cells by using fura-2 as a Ca(2+)-selective fluor...
- Effect of Thimerosal on Ca(2+) Movement and Apoptosis in PC3 Prostate Cancer Cells
[作者：Liao, WC; Chou, CT; Kuo, CC; Pan, CC; Kuo, DH; Shieh, P; Cheng, JS; Jan, CR; Shaw, CF,期刊：Drug Development Research, 页码：330-336 , 文章类型： Article，,卷期：2011年72-4]
- The present study evaluated the effects of thimerosal, a vaccine preservative, on cytosolic free Ca(2+) concentrations ([Ca(2+)](i)) in human prostate cancer cells (PC3). Thimerosal (10-200 mu M) increased [Ca(2+)](i) in...
- PLA Nanoparticles Loaded With an Active Lactone Form of Hydroxycamptothecin: Development, Optimization, and In Vitro-In Vivo Evaluation in Mice Bearing H22 Solid Tumor
[作者：Hou, ZQ; Zhou, CX; Luo, Y; Zhan, CM; Wang, YX; Xie, LY; Zhang, QQ,期刊：Drug Development Research, 页码：337-345 , 文章类型： Article，,卷期：2011年72-4]
- Hydroxycamptothecin (HCPT)-loaded PLA nanoparticles were prepared by a one-step method using the direct dialysis technique, and were examined for particle characteristics, in vitro drug release, and cytotoxicity, as well...
- Cell Screening Assay for Identifying Inhibitors of Eosinophil Proliferation
[作者：Kempe-Dustin, JJ; Aboul-Fadl, T; Christensen, C; Palais, R; Parsawar, K; Gleich, GJ; Wagner, LA,期刊：Drug Development Research, 页码：353-360 , 文章类型： Article，,卷期：2011年72-4]
- The purpose of this study was to develop a cell-based screening assay for identification of small molecules for the treatment of asthma. Eosinophils are leukocytes that contribute to the pathology of asthma. Lidocaine in...
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