- Immunoregulatory and Effector Activities in Human Cutaneous and Mucosal Leishmaniasis: Understanding Mechanisms of Pathology
[作者：Dutra, WO; de Faria, DR; Machado, PRL; Guimaraes, LH; Schriefer, A; Carvalho, E; Gollob, KJ,期刊：Drug Development Research, 页码：430-436 , 文章类型： Article，,卷期：2011年72-6]
- Individuals infected with Leishmania braziliensis may develop the relatively benign localized cutaneous (CL) form or the mucosal (ML) form of the disease, which represents a more severe and mutilating variation. Interact...
- Disseminated Leishmaniasis: Clinical, Immunological, and Therapeutic Aspects
[作者：Elisa, M; Rosa, A; Roberto, P; Machado, L,期刊：Drug Development Research, 页码：437-441 , 文章类型： Article，,卷期：2011年72-6]
- Disseminated leishmaniasis (DL) is a distinct, severe, and emerging form of American tegumentary leishmaniasis. DL has been characterized by more than 10 multiple and pleomorphic cutaneous lesions, distributed in more th...
- Visceral Leishmaniasis: Challenges in Identifying Subclinical Leishmania Infection
[作者：Carneiro, M; Moreno, EC; Goncalves, AV; Lambertucci, JR; Antunes, CMF,期刊：Drug Development Research, 页码：442-450 , 文章类型： Article，,卷期：2011年72-6]
- The major constraint in conducting visceral leishmaniasis (VL) population studies is the difficulty of diagnosing asymptomatic infection. The aims of the present study, conducted in an urban area in the southeast of Braz...
- New Challenges in the Epidemiology and Treatment of Visceral Leishmaniasis in Periurban Areas
[作者：Dupnik, KM; Nascimento, EL; Rodrigues-Neto, JF; Keesen, T; Fernandes, MZ; Duarte, I; Jeronimo, SMB,期刊：Drug Development Research, 页码：451-462 , 文章类型： Article，,卷期：2011年72-6]
- Visceral leishmaniasis (VL) represents a major public health problem in many areas of the world. This review focuses on the impact of periurbanization on the epidemiology and treatment of VL, using Brazil as an example. ...
- Clinical Aspects of Chagas Disease and Implications for Novel Therapies
[作者：Menezes, C; Costa, GC; Gollob, KJ; Dutra, WO,期刊：Drug Development Research, 页码：471-479 , 文章类型： Article，,卷期：2011年72-6]
- The interaction between the protozoan parasite Trypanosoma cruzi and the human host dates back 9,000 years, as demonstrated by molecular analysis of material obtained from Andean mummies indicating the presence of the pa...
- Therapeutic Opportunities in Dengue Infection
[作者：Fagundes, CT; Costa, VV; Cisalpino, D; Souza, DG; Teixeira, MM,期刊：Drug Development Research, 页码：480-500 , 文章类型： Article，,卷期：2011年72-6]
- Infection by one of the four serotypes of the arthropod-borne dengue virus produces a spectrum of disease manifestations, ranging from asymptomatic to life-threatening Dengue hemorrhagic fever/Dengue shock syndrome (DHF/...
- Clinical, Immunological, and Genetic Aspects in Leprosy
[作者：Simon, M; Scherlock, J; Duthie, MS; de Jesus, AR,期刊：Drug Development Research, 页码：509-527 , 文章类型： Article，,卷期：2011年72-6]
- Leprosy is a chronic infection caused by Mycobacterium leprae. It affects the skin and peripheral nerves and can cause irreversible chronic disabilities. The worldwide registered number of cases in 2009 was 213,036. This...
- Schistosoma mansoni Antigens Modulate Allergic Response In Vitro in Cells of Asthmatic Individuals
[作者：Cardoso, LS; Oliveira, SC; Souza, RP; Goes, AM; Oliveira, RR; Alcantara, LM; Almeida, MC; Carvalho, EM; Araujo, MI,期刊：Drug Development Research, 页码：538-548 , 文章类型： Article，,卷期：2011年72-6]
- Schistosoma mansoni infection is associated with a low prevalence of asthma and a less severe form of the disease. The mechanisms underlying this association may include the production of regulatory cells and cytokines. ...
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