- Role of Protein Flexibility in the Discovery of New Drugs
[作者:Fuentes, G; Dastidar, SG; Madhumalar, A; Verma, CS,期刊:Drug Development Research, 页码:26-35 , 文章类型: Article,,卷期:2011年72-1]
- Proteins have inherent flexibility, and this plays a critical role in a vast array of biological functions, including ligand binding. Structure-based drug design (SBDD) strategies incorporate biomolecular structures with...
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