- Twin Study Indicates Loss of Interaction Between Microbiota and Mucosa of Patients With Ulcerative Colitis
[作者:Lepage, P; Hasler, R; Spehlmann, ME; Rehman, A; Zvirbliene, A; Begun, A; Ott, S; Kupcinskas, L; Dore, J; Raedler, A; Schreiber, S,期刊:Gastroenterology, 页码:227-236 , 文章类型: Article,,卷期:2011年141-1]
- BACKGROUND & AIMS: Interactions between genetic and environmental factors are believed to be involved in onset and initiation of inflammatory bowel disease. We analyzed the interaction between gastrointestinal mucosal mi...
- Aryl Hydrocarbon Receptor-Induced Signals Up-regulate IL-22 Production and Inhibit Inflammation in the Gastrointestinal Tract
[作者:Monteleone, I; Rizzo, A; Sarra, M; Sica, G; Sileri, P; Biancone, L; MacDonald, TT; Pallone, F; Monteleone, G,期刊:Gastroenterology, 页码:237-U324 , 文章类型: Article,,卷期:2011年141-1]
- BACKGROUND & AIMS: The pathogenesis of inflammatory bowel disease (IBD) is believed to involve an altered balance between effector and regulatory T cells. Aryl hydrocarbon receptor (AhR), a ligand-dependent transcription...
- Interferon-lambda Mediates Oral Tolerance and Inhibits Antigen-Specific, T-Helper 2 Cell-Mediated Inflammation in Mouse Intestine
[作者:He, SH; Chen, X; Song, CH; Liu, ZQ; Zhou, LF; Ma, WJ; Zhao, LD; Li, TL; Tang, SG; Xing, Z; Yang, PC,期刊:Gastroenterology, 页码:249-U336 , 文章类型: Article,,卷期:2011年141-1]
- BACKGROUND & AIMS: Oral tolerance is an important component of gastrointestinal homeostasis, but mechanisms of its development are not fully understood. Loss of oral tolerance occurs during food allergen-related inflamma...
- The Wnt Antagonist Dkk1 Regulates Intestinal Epithelial Homeostasis and Wound Repair
[作者:Koch, S; Nava, P; Addis, C; Kim, W; Denning, TL; Li, LH; Parkos, CA; Nusrat, A,期刊:Gastroenterology, 页码:259-U354 , 文章类型: Article,,卷期:2011年141-1]
- BACKGROUND & AIMS: Dkk1 is a secreted antagonist of the Wnt/beta-catenin signaling pathway. It is induced by inflammatory cytokines during colitis and exacerbates tissue damage by promoting apoptosis of epithelial cells....
- Differentiated Human Colorectal Cancer Cells Protect Tumor-Initiating Cells From Irinotecan
[作者:Emmink, BL; Van Houdt, WJ; Vries, RG; Hoogwater, FJH; Govaert, KM; Verheem, A; Nijkamp, MW; Steller, EJA; Jimenez, CR; Clevers, H; Rinkes, IHMB; Kranenburg, O,期刊:Gastroenterology, 页码:269-278 , 文章类型: Article,,卷期:2011年141-1]
- BACKGROUND & AIMS: Stem cells of normal tissues have resistance mechanisms that allow them to survive genotoxic insults. The stem cell-like cells of tumors are defined by their tumor-initiating capacity and may have reta...
- SNAIL Regulates Interleukin-8 Expression, Stem Cell-Like Activity, and Tumorigenicity of Human Colorectal Carcinoma Cells
[作者:Hwang, WL; Yang, MH; Tsai, ML; Lan, HY; Su, SH; Chang, SC; Teng, HW; Yang, SH; Lan, YT; Chiou, SH; Wang, HW,期刊:Gastroenterology, 页码:279-U382 , 文章类型: Article,,卷期:2011年141-1]
- BACKGROUND & AIMS: Some cancer cells have activities that are similar to those of stem cells from normal tissues, and cell dedifferentiation correlates with poor prognosis. Little is known about the mechanisms that regul...
- Will There Be an HCV Meeting in 2020? Summary of the 17th International Meeting on Hepatitis C Virus and Related Viruses
[作者:Wakita, T; Suzuki, T; Evans, MJ; Shimotohno, K; Chayama, K; Matsuura, Y; Hijikata, M; Moriishi, K; Seya, T; Enomoto, N; Koike, K; Kato, N; Kanto, T; Hotta, H,期刊:Gastroenterology, 页码:E1-E5 , 文章类型: Editorial Material,,卷期:2011年141-1]
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- BMPR1A Mutations in Hereditary Nonpolyposis Colorectal Cancer Without Mismatch Repair Deficiency
[作者:Nieminen, TT; Abdel-Rahman, WM; Ristimaki, A; Lappalainen, M; Lahermo, P; Mecklin, JP; Jarvinen, HJ; Peltomaki, P,期刊:Gastroenterology, 页码:E23-E26 , 文章类型: Letter,,卷期:2011年141-1]
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- Shanthi V. Sitaraman, MD, PhD Physician, Scientist, Educator, and Humanitarian In Memoriam
[作者:Yang, VW; Anania, FA; Gewirtz, AT; Klapproth, JM; Merlin, D; Srinivasan, S,期刊:Gastroenterology, 页码:1-3 , 文章类型: Biographical-Item,,卷期:2011年141-1]
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