- Effects of MK-886, a leukotriene synthesis inhibitor, on [Ca2+](i) and apoptosis in MG63 human osteosarcoma cells
[作者:Chang, HT; Huang, CC; Cheng, HH; Lu, T; Wang, JL; Lin, KL; Hsu, PT; Tsai, JY; Liao, WC; Lu, YC; Huang, JK; Jan, CR,期刊:Drug Development Research, 页码:49-57 , 文章类型: Article,,卷期:2008年69-2]
The effect of MK-886 (3-[1-(p-chlorobenzyl)-5-(isopropyl)-3-tert-butylthioindol-2-yl]-2, 2-dimethylpropanoic acid), a compound widely used to inhibit leukotriene synthesis, on cytosolic free Ca2+ concentrations ([Ca2+...
- Comparative evaluation of quality of doxycycline formulations registered in Estonia to those registered in the Russian Federation
[作者:Meos, A; Paap, A; Matto, V; Veski, P,期刊:Drug Development Research, 页码:58-68 , 文章类型: Article,,卷期:2008年69-2]
The in vitro properties of four Estonian drug market (manufactured in Austria, Germany, and Finland) and four Russian Federation drug market (manufactured in Belarussia and Russian Federation) doxycycline formulations...
- Iptakalim prevents rat pulmonary hypertension induced by endothelin-1 through the activation of K-ATP channel in vivo
[作者:Wang, H; Xie, WP; Zhang, Z; Wang, H; Hu, G; Zhang, SJ,期刊:Drug Development Research, 页码:89-94 , 文章类型: Article,,卷期:2008年69-2]
Iptakalim has been previously characterized as a novel, selective ATP-sensitive potassium channel opener. In the present study, to determine whether iptakalim can prevent the pulmonary hypertension induced by endothel...
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