- Combination Therapy of Tacrolimus and Infliximab Reduces Inflammatory Response and Dysmotility in Experimental Small Bowel Transplantation in Rats
[作者:Pech, T; Fujishiro, J; Finger, T; Ohsawa, I; Praktiknjo, M; Abu-Elmagd, K; von Websky, M; Overhaus, M; Kalff, JC; Schaefer, N,期刊:Transplantation, 页码:249-256 , 文章类型: Article,,卷期:2012年93-3]
- Background. Intestinal transplantation initiates a functionally relevant inflammatory response by activation of resident macrophages within the muscularis associated with dysmotility. Infliximab is used successfully as a...
- Profiling Posttransplant Circulating Antibodies in Kidney Transplantation Using Donor Endothelial Cells
[作者:Canet, E; Devalliere, J; Gerard, N; Karam, G; Giral, M; Charreau, B; Coupel, S,期刊:Transplantation, 页码:257-264 , 文章类型: Article,,卷期:2012年93-3]
- Background. Pathogenesis of antibody (Ab) responses to transplant are yet not well defined. This study aimed to detect and to analyze posttransplant circulating allo-Abs reacting toward graft endothelial cells (ECs) usin...
- Myeloid-Derived Suppressor Cells Protect Islet Transplants by B7-H1 Mediated Enhancement of T Regulatory Cells
[作者:Chou, HS; Hsieh, CC; Charles, R; Wang, LF; Wagner, T; Fung, JJ; Qian, SG; Lu, LNL,期刊:Transplantation, 页码:272-282 , 文章类型: Article,,卷期:2012年93-3]
- Background. Side effects of lifetime immunosuppression for cell transplants often outweigh the benefits; therefore, induction of transplant tolerance is needed. We have shown that cotransplantation with myeloid-derived s...
- Pretransplant Immune Regulation Predicts Allograft Outcome: Bidirectional Regulation Correlates With Excellent Renal Transplant Function in Living-Related Donor-Recipient Pairs
[作者:Jankowska-Gan, E; Sheka, A; Sollinger, HW; Pirsch, JD; Hofmann, RM; Haynes, LD; Armbrust, MJ; Mezrich, JD; Burlingham, WJ,期刊:Transplantation, 页码:283-290 , 文章类型: Article,,卷期:2012年93-3]
- Background. Tolerance to noninherited maternal antigens has provided clinical advantage when kidney transplants are exchanged between siblings but not when mother herself is the donor. This paradox prompted us to revisit...
- Lower Prevalence of BK Virus Infection in African American Renal Transplant Recipients: A Prospective Study
[作者:Sood, P; Senanayake, S; Sujeet, K; Medipalli, R; Saad, E; Vasudev, B; Bresnahan, BA; Johnson, CP; Hariharan, S,期刊:Transplantation, 页码:291-296 , 文章类型: Article,,卷期:2012年93-3]
- Background. Because the occurrence of BK virus (BKV) nephritis is far less frequent than BK viremia or viruria, analysis of risk factors for BKV nephritis as an endpoint could lead to erroneous findings. We undertook a p...
- Early Association of Low-Grade Albuminuria and Allograft Dysfunction Predicts Renal Transplant Outcomes
[作者:Hernandez, D; Perez, G; Marrero, D; Porrini, E; Rufino, M; Gonzalez-Posada, JM; Delgado, P; Torres, A,期刊:Transplantation, 页码:297-303 , 文章类型: Article,,卷期:2012年93-3]
- Background. Data on the combined associations of albuminuria and estimated glomerular filtration rate (eGFR) with renal transplant outcomes are limited. Our objective was to explore how renal transplant outcomes could be...
- Ureteral Stents Are Associated With Reduced Risk of Ureteral Complications After Kidney Transplantation: A Large Single Center Experience
[作者:Fayek, SA; Keenan, J; Haririan, A; Cooper, M; Barth, RN; Schweitzer, E; Bromberg, JS; Bartlett, ST; Philosophe, B,期刊:Transplantation, 页码:304-308 , 文章类型: Article,,卷期:2012年93-3]
- Background. Controversy exists regarding the benefit of ureteral stents in kidney transplantation. We aimed to examine the association of stents with risk of ureteral complications, particularly in relationship with dono...
- Low Serum IGF-1 Is a Risk Factor for Cardiac Allograft Vasculopathy in Cardiac Transplant Recipients
[作者:Aharinejad, S; Salama, M; Rodler, S; Ehrlich, M; Zuckermann, A; Laufer, G,期刊:Transplantation, 页码:309-313 , 文章类型: Article,,卷期:2012年93-3]
- Background. Cardiac allograft vasculopathy (CAV) has an incidence of 43% at 8 years after heart transplantation with extremely limited treatment options and unclear pathogenesis. CAV constitutes a significant complicatio...
- Rapid Reduction in Donor-Specific Anti-Human Leukocyte Antigen Antibodies and Reversal of Antibody-Mediated Rejection With Bortezomib in Pediatric Heart Transplant Patients
[作者:Morrow, WR; Frazier, EA; Mahle, WT; Harville, TO; Pye, SE; Knecht, KR; Howard, EL; Smith, RN; Saylors, RL; Garcia, X; Jaquiss, RDB; Woodle, ES,期刊:Transplantation, 页码:319-324 , 文章类型: Article,,卷期:2012年93-3]
- Background. High titer donor-specific antibodies (DSA) and positive crossmatch in cardiac transplant recipients is associated with increased mortality from antibody-mediated rejection (AMR). Although treatment to reduce ...
- Genetic Polymorphisms of the Transcription Factor NFATc4 and Development of New-Onset Diabetes After Transplantation in Hispanic Kidney Transplant Recipients
[作者:Chen, Y; Sampaio, MS; Yang, JW; Min, D; Hutchinson, IV,期刊:Transplantation, 页码:325-330 , 文章类型: Article,,卷期:2012年93-3]
- Transcription factors of the nuclear factor of activated T cells (NFAT) family regulate both immune activation and insulin production. Calcineurin inhibitors (CNIs) target NFAT activation. Hence, CNIs not only prevent or...
- Ibandronate and Calcitriol Reduces Fracture Risk, Reverses Bone Loss, and Normalizes Bone Turnover After lTX
[作者:Wagner, D; Amrein, K; Dimai, HP; Kniepeiss, D; Tscheliessnigg, KH; Kornprat, P; Dobnig, H; Pieber, T; Fahrleitner-Pammer, A,期刊:Transplantation, 页码:331-336 , 文章类型: Article,,卷期:2012年93-3]
- Background. Osteoporosis is a common complication in long-term survivors after liver transplantation (LTX). This study investigates the influence of a combination therapy of low dose parenteral ibandronate (IBN) and calc...
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