- ANXA8 Down-regulation by EGF-FOXO4 Signaling Is Involved in Cell Scattering and Tumor Metastasis of Cholangiocarcinoma
[作者:Lee, MJ; Yu, GR; Yoo, HJ; Kim, JH; Yoon, BI; Choi, YK; Kim, DG,期刊:Gastroenterology, 页码:1138-1150 , 文章类型: Article,,卷期:2009年137-3]
- BACKGROUND & AIMS: The sarcomatoid change in cholangiocarcinoma (CC) contributes to more aggressive intrahepatic spread and widespread metastasis. Therefore, the aim of this study was to identify the molecular mechanisms...
- Human and Mouse Colon Cancer Utilizes CD95 Signaling for Local Growth and Metastatic Spread to Liver
[作者:Li, HC; Fan, XL; Stoicov, C; Liu, JH; Zubair, S; Tsai, E; Ste Marie, R; Wang, TC; Lyle, S; Kurt-Jones, E; Houghton, J,期刊:Gastroenterology, 页码:934-944 , 文章类型: Article,,卷期:2009年137-3]
- BACKGROUND & AIMS: Analysis of clinical colon cancer specimens show alterations in the CD95 (Fas Ag/Fas L) pathway as tumors progress from local to metastatic disease, suggesting that this pathway may play a role in inva...
- Saccharomyces boulardii Inhibits EGF Receptor Signaling and Intestinal Tumor Growth in Apc(min) Mice
[作者:Chen, XH; Fruehauf, J; Goldsmith, JD; Xu, H; Katchar, KK; Koon, HW; Zhao, DZ; Kokkotou, EG; Pothoulakis, C; Kelly, CP,期刊:Gastroenterology, 页码:914-923 , 文章类型: Article,,卷期:2009年137-3]
- BACKGROUND & AIMS: Saccharomyces boulardii (Sb) is a probiotic yeast with anti-inflammatory and antimicrobial activities and has been used for decades in the prevention and treatment of a variety of human gastrointestina...
- Combined Targeted Treatment to Eliminate Tumorigenic Cancer Stem Cells in Human Pancreatic Cancer
[作者:Mueller, MT; Hermann, PC; Witthauer, J; Rubio-Viqueira, B; Leicht, SF; Huber, S; Ellwart, JW; Mustafa, M; Bartenstein, P; D'Haese, JG; Schoenberg, MH; Berger, F; Jauch, KW; Hidalgo, M; Heeschen, C,期刊:Gastroenterology, 页码:1102-1113 , 文章类型: Article,,卷期:2009年137-3]
- BACKGROUND & AIMS: Pancreatic cancers contain exclusively tumorigenic cancer stem cells (CSCs), which are highly resistant to chemotherapy, resulting in a relative increase in CSC numbers during gemcitabine treatment. Si...
- Mucosal Addressin Cell-Adhesion Molecule-1 Controls Plasma-Cell Migration and Function in the Small Intestine of Mice
[作者:Schippers, A; Leuker, C; Pabst, O; Kochut, A; Prochnow, B; Gruber, AD; Leung, E; Krissansen, GW; Wagner, N; Muller, W,期刊:Gastroenterology, 页码:924-933 , 文章类型: Article,,卷期:2009年137-3]
- BACKGROUND & AIMS: Immunoglobulin (Ig) A secretion into the intestinal lumen is an important immune mechanism of the gastrointestinal (GI) tract. B cells proliferate and differentiate into IgA-secreting plasma cells (PC)...
- A System of Classifying Microvascular Invasion to Predict Outcome After Resection in Patients With Hepatocellular Carcinoma
[作者:Roayaie, S; Blume, IN; Thung, SN; Guido, M; Fiel, MI; Hiotis, S; Labow, DM; Llovet, JM; Schwartz, ME,期刊:Gastroenterology, 页码:850-855 , 文章类型: Article,,卷期:2009年137-3]
- BACKGROUND & AIMS: Hepatocellular carcinoma (HCC) recurs in approximately 70% of cases after resection. Vascular invasion by tumor cells can be classified as gross or microscopic (microvascular invasion [mVI]) and is a r...
- Intravenous N-Acetylcysteine Improves Transplant-Free Survival in Early Stage Non-Acetaminophen Acute Liver Failure
[作者:Lee, WM; Hynan, LS; Rossaro, L; Fontana, RJ; Stravitz, RT; Larson, AM; Davern, TJ; Murray, NG; McCashland, T; Reisch, JS; Robuck, PR,期刊:Gastroenterology, 页码:856-864 , 文章类型: Article,,卷期:2009年137-3]
- BACKGROUND & AIMS: N-acetylcysteine (NAC), an antidote for acetaminophen poisoning, might benefit patients with non-acetaminophen-related acute liver failure. METHODS: In a prospective, double-blind trial, acute liver fa...
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