- Cannabinoid Type 1 Receptor Antagonism Delays Ascites Formation in Rats With Cirrhosis
[作者:Domenicali, M; Caraceni, P; Giannone, F; Pertosa, AM; Principe, A; Zambruni, A; Trevisani, F; Croci, T; Bernardi, M,期刊:Gastroenterology, 页码:341-349 , 文章类型: Article,,卷期:2009年137-1]
- BACKGROUND & AIMS: Endocannabinoids contribute to hemodynamic abnormalities of cirrhosis. Whether this favors renal sodium retention and ascites formation is unknown. We determined whether cannabinoid type 1. receptor an...
- Colony Stimulating Factor-1 Dependence of Paneth Cell Development in the Mouse Small Intestine
[作者:Huynh, D; Dai, XM; Nandi, S; Lightowler, S; Trivett, M; Chan, CK; Bertoncello, I; Ramsay, RG; Stanley, ER,期刊:Gastroenterology, 页码:136-144 , 文章类型: Article,,卷期:2009年137-1]
- BACKGROUND & AIMS: Paneth cells (PCs) secrete defensins and antimicrobial enzymes that contribute to innate immunity against pathogen infections within the mucosa of the small intestine. We examined the role of colony st...
- Mechanisms of Neural Response to Gastrointestinal Nutritive Stimuli: The Gut-Brain Axis
[作者:Tsurugizawa, T; Uematsu, A; Nakamura, E; Hasumura, M; Hirota, M; Kondoh, T; Uneyama, H; Torii, K,期刊:Gastroenterology, 页码:262-273 , 文章类型: Article,,卷期:2009年137-1]
- BACKGROUND & AIMS: The gut-brain axis, which transmits nutrient information from the gastrointestinal tract to the brain, is important for. the detection of dietary nutrients. We used functional magnetic resonance imagin...
- Notch Signaling Promotes the Generation of EphrinB1-Positive Intestinal Epithelial Cells
[作者:Koo, BK; Lim, HS; Chang, HJ; Yoon, MJ; Choi, Y; Kong, MP; Kim, CH; Kim, JM; Park, JG; Kong, YY,期刊:Gastroenterology, 页码:145-155 , 文章类型: Article,,卷期:2009年137-1]
- BACKGROUND & AIMS: The intestinal epithelium consists of EphB2-positive proliferative basal cryptic cells and Ephrin B1-positive, postmitotic differentiated cells. We investigated the effects of Notch signaling on format...
- alpha-Fetoprotein, Des-gamma Carboxyprothrombin, and Lectin-Bound alpha-Fetoprotein in Early Hepatocellular Carcinoma
[作者:Marrero, JA; Feng, ZD; Wang, YH; Nguyen, MH; Befeler, AS; Roberts, LR; Reddy, KR; Harnois, D; Llovet, JM; Normolle, D; Dalhgren, J; Chia, D; Lok, AS; Wagner, PD; Srivastava, S; Schwartz, M,期刊:Gastroenterology, 页码:110-118 , 文章类型: Article,,卷期:2009年137-1]
- BACKGROUND & AIMS: alpha-Fetoprotein (AFP) is widely used as a surveillance test for hepatoceitular carcinoma (HCC) among patients with cirrhosis. Des-gamma carboxy-prothrombin (DCP) and lectin-bound AFP (AFP-L3%) are po...
- Hepatitis C Virus and Disrupted Interferon Signaling Promote Lymphoproliferation via Type II CD95 and Interleukins
[作者:Machida, K; Tsukiyama-Kohara, K; Sekiguch, S; Seike, E; Tone, S; Hayashi, Y; Tobita, Y; Kasama, Y; Shimizu, M; Takahashi, H; Taya, C; Yonekawa, H; Tanaka, N; Kohara, M,期刊:Gastroenterology, 页码:285-296 , 文章类型: Article,,卷期:2009年137-1]
- BACKGROUND & AIMS: The molecular mechanisms of lymphoproliferation associated with the disruption of interferon (IFN) signaling and chronic hepatitis C virus (HCV) infection are poorly understood. Lymphomas are extrahepa...
- c-Met Confers Protection Against Chronic Liver Tissue Damage and Fibrosis Progression After Bile Duct Ligation in Mice
[作者:Giebeler, A; Boekschoten, MV; Klein, C; Borowiak, M; Birchmeier, C; Gassler, N; Wasmuth, HE; Muller, M; Trautwein, C; Streetz, KL,期刊:Gastroenterology, 页码:297-308 , 文章类型: Article,,卷期:2009年137-1]
- BACKGROUND & AIMS: The hepatocyte growth factor (HGF)/mesenchymal-epithelial transition factor (c-Met) system is an essential inducer of heparocyte growth and proliferation. Although a fundamental role for the HGF recept...
- E-Cadherin Regulates Metastasis of Pancreatic Cancer In Vivo and Is Suppressed by a SNAIL/HDAC1/HDAC2 Repressor Complex
[作者:von Burstin, J; Eser, S; Paul, MC; Seidler, B; Brandl, M; Messer, M; von Werder, A; Schmidt, A; Mages, J; Pagel, P; Schnieke, A; Schmid, RM; Schneider, G; Saur, D,期刊:Gastroenterology, 页码:361-371 , 文章类型: Article,,卷期:2009年137-1]
- BACKGROUND & AIMS: Early metastasis is a hallmark of pancreatic ductal adenocarcinoma and responsible for >90% of pancreatic cancer death. Because little is known about the biology and genetics of the metastatic process,...
- Laminin gamma 2 Mediates Wnt5a-Induced Invasion of Gastric Cancer Cells
[作者:Yamamoto, H; Kitadai, Y; Yamamoto, H; Oue, N; Ohdan, H; Yasui, W; Kikuchi, A,期刊:Gastroenterology, 页码:242-252 , 文章类型: Article,,卷期:2009年137-1]
- BACKGROUND & AIMS: Wnt5a expression stimulates in vitro migration and invasion of cultured gastric cancer cells by an unknown mechanism and is also correlated with aggressiveness of gastric tumors. The aim of this study ...
- Antifibrotic Effects of CXCL9 and Its Receptor CXCR3 in Livers of Mice and Humans
[作者:Wasmuth, HE; Lammert, F; Zaldivar, MM; Weiskirchen, R; Hellerbrand, C; Scholten, D; Berres, ML; Zimmermann, H; Streetz, KL; Tacke, F; Hillebrandt, S; Schmitz, P; Keppeler, H; Berg, T; Dahl, E; Gassler, N; Friedman, SL; Trautwein, C,期刊:Gastroenterology, 页码:309-319 , 文章类型: Article,,卷期:2009年137-1]
- BACKGROUND & AIMS: Fibrosis is the hallmark of chronic liver diseases, yet many aspects of its mechanism remain to be defined. Chemokines are ubiquitous chemotactic molecules that mediate many acute and chronic inflammat...
- Frequency of Mitochondrial Defects in Patients With Chronic Intestinal Pseudo-Obstruction
[作者:Amiot, A; Tchikviladze, M; Joly, F; Slama, A; Hatem, DC; Jardel, C; Messing, B; Lombes, A,期刊:Gastroenterology, 页码:101-109 , 文章类型: Article,,卷期:2009年137-1]
- BACKGROUND & AIMS: Chronic intestinal pseudo-obstruction (CIPO) is a rare disorder caused by intestinal dysmotility and characterized by chronic symptoms suggesting bowel obstruction in the absence of fixed, occluding le...
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