- Endocrine Characterization of the Reproductive Axis in Highly Prolific Lacaune Sheep Homozygous for the FecL(L) Mutation
[作者:Drouilhet, L; Taragnat, C; Fontaine, J; Duittoz, A; Mulsant, P; Bodin, L; Fabre, S,期刊:Biology of Reproduction, 页码:815-824 , 文章类型: Article,,卷期:2010年82-5]
- A prolific allele named FecL(L) is known to segregate in the meat breed of the French Lacaune sheep on the basis of ovulation rate record. To gain more knowledge about the physiological effects of FecL(L), ewes homozygou...
- Interdependence of Platelet-Derived Growth Factor and Estrogen-Signaling Pathways in Inducing Neonatal Rat Testicular Gonocytes Proliferation
[作者:Thuillier, R; Mazer, M; Manku, G; Boisvert, A; Wang, Y; Culty, M,期刊:Biology of Reproduction, 页码:825-836 , 文章类型: Article,,卷期:2010年82-5]
- We previously found that platelet-derived growth factor (PDGF) and 17beta-estradiol stimulate gonocyte proliferation in a dose-dependent, nonadditive manner. In the present study, we report that gonocytes express RAF1, M...
- Milk Secretion and Ejection Are Impaired in the Mammary Gland of Mice Harboring a Cx43 Mutant While Expression and Localization of Tight and Adherens Junction Proteins Remain Unchanged
[作者:Plante, I; Wallis, A; Shao, Q; Laird, DW,期刊:Biology of Reproduction, 页码:837-847 , 文章类型: Article,,卷期:2010年82-5]
- During pregnancy, the integrity of the mammary gland epithelium must be maintained by the junctional nexus formed by gap, adherens, and tight junctions for proper alveologenesis. We have previously shown that mammary gla...
- Cathepsin B, Cathepsin L, and Cystatin C in the Porcine Uterus and Placenta: Potential Roles in Endometrial/Placental Remodeling and in Fluid-Phase Transport of Proteins Secreted by Uterine Epithelia Across Placental Areolae
[作者:Song, G; Bailey, DW; Dunlap, KA; Burghardt, RC; Spencer, TE; Bazer, FW; Johnson, GA,期刊:Biology of Reproduction, 页码:854-864 , 文章类型: Article,,卷期:2010年82-5]
- Cathepsins (CTSB and CTSL1) and their inhibitor, cystatin C (CST3), remodel uterine endometrium and placenta for transport of gases, micronutrients, and macromolecules essential for development and growth of the conceptu...
- The Sphingosine 1-Phosphate (S1P) Signaling Pathway Is Regulated During Pregnancy in Sheep
[作者:Dunlap, KA; Kwak, HI; Burghardt, RC; Bazer, FW; Magness, RR; Johnson, GA; Bayless, KJ,期刊:Biology of Reproduction, 页码:876-887 , 文章类型: Article,,卷期:2010年82-5]
- Because sphingosine 1-phosphate (S1P) is a potent stimulator of angiogenesis, we hypothesized that the S1P pathway is activated to stimulate endometrial/placental angiogenesis during pregnancy. We initially localized S1P...
- Chub Mackerel Gonads Support Colonization, Survival, and Proliferation of Intraperitoneally Transplanted Xenogenic Germ Cells
[作者:Yazawa, R; Takeuchi, Y; Higuchi, K; Yatabe, T; Kabeya, N; Yoshizaki, G,期刊:Biology of Reproduction, 页码:896-904 , 文章类型: Article,,卷期:2010年82-5]
- The production of xenogenic gametes from large-bodied, commercially important marine fish species in closely related smaller host fish species with short generation times may enable rapid and simple seed production of th...
- Paracrine Factors from Human Placental Multipotent Mesenchymal Stromal Cells Protect Endothelium from Oxidative Injury via STAT3 and Manganese Superoxide Dismutase Activation
[作者:Liu, SH; Huang, JP; Lee, RKK; Huang, MC; Wu, YH; Chen, CY; Chen, CP,期刊:Biology of Reproduction, 页码:905-913 , 文章类型: Article,,卷期:2010年82-5]
- Reactive oxygen species may cause oxidative damage in the placenta, yet some mechanisms must exist to reduce or prevent such damage. We investigated whether oxidative injury to placental endothelial cells is inhibited by...
- The Environmental Toxicant 2,3,7,8-Tetrachlorodibenzo-p-Dioxin Disturbs the Establishment and Maintenance of Cell Polarity in Preimplantation Rat Embryos
[作者:Hutt, KJ; Shi, ZQ; Petroff, BK; Albertini, DF,期刊:Biology of Reproduction, 页码:914-920 , 文章类型: Article,,卷期:2010年82-5]
- Maternal exposure to the environmental toxicant 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) induces a variety of defects in compaction-stage embryos, including monopolar spindle formation, errors in chromosome segregation...
- USP8, a Regulator of Endosomal Sorting, Is Involved in Mouse Acrosome Biogenesis Through Interaction with the Spermatid ESCRT-0 Complex and Microtubules
[作者:Berruti, G; Ripolone, M; Ceriani, M,期刊:Biology of Reproduction, 页码:930-939 , 文章类型: Article,,卷期:2010年82-5]
- Ubiquitin-specific peptidase 8 (USP8) is a deubiquitinating enzyme that works as a regulator of endosomal sorting and vesicle morphology in cultured cells. Its function in vivo is, however, unknown as USP8 gene deletion ...
- Absence of Estrogen Receptor Alpha Leads to Physiological Alterations in the Mouse Epididymis and Consequent Defects in Sperm Function
[作者:Joseph, A; Hess, RA; Schaeffer, DJ; Ko, C; Hudgin-Spivey, S; Chambon, P; Shur, BD,期刊:Biology of Reproduction, 页码:948-957 , 文章类型: Article,,卷期:2010年82-5]
- Male mice deficient in ESR1 (ERalpha) (Esr1KO mice) are infertile, and sperm recovered from the cauda epididymis exhibit reduced motility and fail to fertilize eggs in vitro. These effects on sperm appear to result from ...
- Epididymal Hypo-Osmolality Induces Abnormal Sperm Morphology and Function in the Estrogen Receptor Alpha Knockout Mouse
[作者:Joseph, A; Shur, BD; Ko, C; Chambon, P; Hess, RA,期刊:Biology of Reproduction, 页码:958-967 , 文章类型: Article,,卷期:2010年82-5]
- Estrogen receptor-alpha (ESR1) is highly expressed in the efferent ductules of all species studied as well as in the epididymal epithelium in mice and other select species. Male mice lacking ESR1 (Esr1KO) are infertile, ...
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