- Safety and efficacy of oxaliplatin and fluoropyrimidine regimens with or without bevacizumab as first-line treatment of metastatic colorectal cancer: Results of the TREE study
[作者:Hochster, HS; Hart, LL; Ramanathan, RK; Childs, BH; Hainsworth, JD; Cohn, AL; Wong, L; Fehrenbacher, L; Abubakr, Y; Saif, MW; Schwartzberg, L; Hedrick, E,期刊:Journal of clinical oncology, 页码:3523-3529 , 文章类型: Article,,卷期:2008年26-21]
- PurposeTo evaluate the safety and efficacy of three oxaliplatin and fluoropyrimidine regimens, with or without bevacizumab, as first-line treatment for metastatic colorectal cancer (CRC).Patients and MethodsPatients with...
- Impact of immediate versus delayed axillary node dissection on surgical outcomes in breast cancer patients with positive sentinel nodes: Results from American College of Surgeons Oncology Group trials Z0010 and Z0011
[作者:Olson, JA; McCall, LM; Beitsch, P; Whitworth, PW; Reintgen, DS; Blumencranz, PW; Leitch, AM; Saha, S; Hunt, KK; Giuliano, AE,期刊:Journal of clinical oncology, 页码:3530-3535 , 文章类型: Article,,卷期:2008年26-21]
- PurposePatients with breast cancer metastasis to the sentinel lymph nodes (SLNs) generally undergo completion axillary lymph node dissection (cALND), either concurrently with SLN biopsy or at a second procedure. The impa...
- Pooled analysis of the effect of age on adjuvant cisplatin-based chemotherapy for completely resected non-small-cell lung cancer
[作者:Fruh, M; Rolland, E; Pignon, JP; Seymour, L; Ding, K; Tribodet, H; Winton, T; Le Chevalier, T; Scagliotti, GV; Douillard, JY; Spiro, S; Shepherd, FA,期刊:Journal of clinical oncology, 页码:3573-3581 , 文章类型: Article,,卷期:2008年26-21]
- PurposeThis pooled analysis was undertaken to assess the efficacy and toxicity of adjuvant cisplatin-based chemotherapy in elderly patients with non-small-cell lung cancer (NSCLC).MethodsWe used individual patient data f...
- Factors associated with severe late toxicity after concurrent chemoradiation for locally advanced head and neck cancer: An RTOG analysis
[作者:Machtay, M; Moughan, J; Trotti, A; Garden, AS; Weber, RS; Cooper, JS; Forastiere, A; Ang, KK,期刊:Journal of clinical oncology, 页码:3582-3589 , 文章类型: Article,,卷期:2008年26-21]
- PurposeConcurrent chemoradiotherapy (CCRT) for squamous cell carcinoma of the head and neck (SCCHN) increases both local tumor control and toxicity. This study evaluates clinical factors that are associated with and migh...
- Lymphedema after breast cancer: Incidence, risk factors, and effect on upper body function
[作者:Hayes, SC; Janda, M; Cornish, B; Battistutta, D; Newman, B,期刊:Journal of clinical oncology, 页码:3536-3542 , 文章类型: Article,,卷期:2008年26-21]
- PurposeSecondary lymphedema is associated with adverse physical and psychosocial consequences among women with breast cancer (BC). This article describes the prevalence and incidence of lymphedema between 6 and 18 months...
- Phase III study comparing cisplatin plus gemcitabine with cisplatin plus pemetrexed in chemotherapy-naive patients with advanced-stage non-small-cell lung cancer
[作者:Scagliotti, GV; Parikh, P; von Pawel, J; Biesma, B; Vansteenkiste, J; Manegold, C; Serwatowski, P; Gatzemeier, U; Digumarti, R; Zukin, M; Lee, JS; Mellemgaard, A; Park, K; Patil, S; Rolski, J; Goksel, T; de Marinis, F; Simms, L; Sugarman, KP; Gandara, D,期刊:Journal of clinical oncology, 页码:3543-3551 , 文章类型: Article,,卷期:2008年26-21]
- PurposeCisplatin plus gemcitabine is a standard regimen for first-line treatment of advanced non-small-cell lung cancer (NSCLC). Phase II studies of pemetrexed plus platinum compounds have also shown activity in this set...
- Lung Adjuvant Cisplatin Evaluation: A pooled analysis by the LACE collaborative group
[作者:Pignon, JP; Tribodet, H; Scagliotti, GV; Douillard, JY; Shepherd, FA; Stephens, RJ; Dunant, A; Torri, V; Rosell, R; Seymour, L; Spiro, SG; Rolland, E; Fossati, R; Aubert, D; Ding, K; Waller, D; Le Chevalier, T,期刊:Journal of clinical oncology, 页码:3552-3559 , 文章类型: Article,,卷期:2008年26-21]
- PurposeSeveral recent trials have shown a significant overall survival (OS) benefit from postoperative cisplatin-based chemotherapy in patients with non-small-cell lung cancer (NSCLC). The aim of the Lung Adjuvant Cispla...
- DNA damage and repair capacity in patients with lung cancer: Prediction of multiple primary tumors
[作者:Orlow, I; Park, BJ; Mujumdar, U; Patel, H; Siu-Lau, P; Clas, BA; Downey, R; Flores, R; Bains, M; Rizk, N; Dominguez, G; Jani, J; Berwick, M; Begg, CB; Kris, MG; Rusch, VW,期刊:Journal of clinical oncology, 页码:3560-3566 , 文章类型: Article,,卷期:2008年26-21]
- PurposePatients who survive one occurrence of non-small-cell lung cancer (NSCLC) are at higher risk of a second malignancy. Capacity to repair damaged DNA may modulate individual susceptibility to develop lung cancer. Th...
- Pemetrexed plus gemcitabine as first-line chemotherapy for patients with peritoneal mesothelioma: Final report of a phase II trial
[作者:Simon, GR; Verschraegen, CF; Janne, PA; Langer, CJ; Dowlati, A; Gadgeel, SM; Kelly, K; Kalemkerian, GP; Traynor, AM; Peng, G; Gill, J; Obasaju, CK; Kindler, HL,期刊:Journal of clinical oncology, 页码:3567-3572 , 文章类型: Article,,卷期:2008年26-21]
- PurposePemetrexed in combination with cisplatin is approved for the treatment of pleural mesothelioma and is active in malignant peritoneal mesothelioma (MPeM). Pemetrexed and gemcitabine are synergistic in preclinical m...
- Preoperative gemcitabine and cisplatin followed by gemcitabine-based chemoradiation for resectable adenocarcinoma of the pancreatic head
[作者:Varadhachary, GR; Wolff, RA; Crane, CH; Sun, CC; Lee, JE; Pisters, PWT; Vauthey, JN; Abdalla, E; Wang, H; Staerkel, GA; Lee, JH; Ross, WA; Tamm, EP; Bhosale, PR; Krishnan, S; Das, P; Ho, L; Xiong, H; Abbruzzese, JL; Evans, DB,期刊:Journal of clinical oncology, 页码:3487-3495 , 文章类型: Article,,卷期:2008年26-21]
- PurposeWe conducted a phase II trial of preoperative gemcitabine and cisplatin chemotherapy in addition to chemoradiation (Gem-Cis-XRT) and pancreaticoduodenectomy (PD) for patients with stage I/II pancreatic adenocarcin...
- Preoperative gemcitabine-based chemoradiation for patients with resectable adenocarcinoma of the pancreatic head
[作者:Evans, DB; Varadhachary, GR; Crane, CH; Sun, CC; Lee, JE; Pisters, PWT; Vauthey, JN; Wang, H; Cleary, KR; Staerkel, GA; Charnsangavej, C; Lano, EA; Ho, L; Lenzi, R; Abbruzzese, JL; Wolff, RA,期刊:Journal of clinical oncology, 页码:3496-3502 , 文章类型: Article,,卷期:2008年26-21]
- Purpose We conducted a phase II trial to assess the outcomes of patients who received preoperative gemcitabine-based chemoradiation and pancreaticoduodenectomy (PD) for stage I/II pancreatic adenocarcinoma.Patients and M...
- Analysis of fluorouracil-based adjuvant chemotherapy and radiation after pancreaticoduodenectomy for ductal adenocarcinoma of the pancreas: Results of a large, prospectively collected database at the Johns Hopkins hospital
[作者:Herman, JM; Swartz, MJ; Hsu, CC; Winter, J; Pawlik, TM; Sugar, E; Robinson, R; Laheru, DA; Jaffee, E; Hruban, RH; Campbell, KA; Wolfgang, CL; Asrari, F; Donehower, R; Hidalgo, M; Diaz, LA; Yeo, C; Cameron, JL; Schulick, RD; Abrams, R,期刊:Journal of clinical oncology, 页码:3503-3510 , 文章类型: Article,,卷期:2008年26-21]
- PurposeTo examine the efficacy of adjuvant chemoradiotherapy after pancreaticoduodenectomy (PD) for pancreatic adenocarcinoma (PC) in patients undergoing resection at Johns Hopkins Hospital (JHH; Baltimore, MD).Patients ...
- Adjuvant radiotherapy and chemotherapy for pancreatic carcinoma: The Mayo Clinic experience (1975-2005)
[作者:Corsini, MM; Miller, RC; Haddock, MG; Donohue, JH; Farnell, MB; Nagorney, DM; Jatoi, A; McWilliams, RR; Kim, GP; Bhatia, S; Iott, MJ; Gunderson, LL,期刊:Journal of clinical oncology, 页码:3511-3516 , 文章类型: Article,,卷期:2008年26-21]
- PurposeTo determine prognostic factors and impact of adjuvant chemotherapy (CT) and radiotherapy (RT) on overall survival (OS) after resection of pancreatic adenocarcinoma.Patients and MethodsWe performed a retrospective...
- Evidence of the oncologic superiority of cylindrical abdominoperineal excision for low rectal cancer
[作者:West, NP; Finan, PJ; Anderin, C; Lindholm, J; Holm, T; Quirke, P,期刊:Journal of clinical oncology, 页码:3517-3522 , 文章类型: Article,,卷期:2008年26-21]
- PurposeAbdominoperineal excision (APE) of the rectum and anus for rectal cancer continues to have greater local recurrence and poorer survival than that seen following anterior resection. Changing to an extended prone pe...
- Mature and immature extracranial teratomas in children: The UK Children's Cancer Study Group experience
[作者:Mann, JR; Gray, ES; Thornton, C; Raafat, F; Robinson, K; Collins, GS; Gornall, P; Huddart, SN; Hale, JP; Oakhill, A,期刊:Journal of clinical oncology, 页码:3590-3597 , 文章类型: Article,,卷期:2008年26-21]
- PurposeThe purpose of this article is to describe the features, treatment, and risk factors for relapse of children with mature teratoma (MT) and immature teratoma (IT) to assist future treatment plans.Patients and Metho...
- Relationship between ERCC1 polymorphisms, disease progression, and survival in the gynecologic oncology group phase III trial of intraperitoneal versus intravenous cisplatin and paclitaxel for stage III epithelial ovarian cancer
[作者:Krivak, TC; Darcy, KM; Tian, C; Armstrong, D; Baysal, BE; Gallion, H; Ambrosone, CB; DeLoia, JA,期刊:Journal of clinical oncology, 页码:3598-3606 , 文章类型: Article,,卷期:2008年26-21]
- PurposeWe hypothesized that common polymorphisms in excision repair cross-complementation group 1 (ERCC1), involved in nucleotide excision repair of platinum-induced damage, would be associated with progression-free surv...
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