- Antileukemic activity of genistein, a major isoflavone present in soy products
[作者:Raynal, NJM; Momparler, L; Charbonneau, M; Momparler, RL,期刊:Journal of natural products, 页码:3-7 , 文章类型: Article,,卷期:2008年71-1]
- Soy has been used in traditional medicine for the treatment of various diseases, including cancer. The isoflavones present in soy have been shown in animal models to have cancer-preventing activity. However, the therapeu...
- Polydiscamides B-D from a marine sponge Ircinia sp as potent human sensory neuron-specific G protein coupled receptor agonists
[作者:Feng, YJ; Carroll, AR; Pass, DM; Archbold, JK; Avery, VM; Quinn, RJ,期刊:Journal of natural products, 页码:8-11 , 文章类型: Article,,卷期:2008年71-1]
- Polydiscamides B, C, and D (1-3) were isolated from a sponge Ircinia sp. The structures of 1 to 3 were elucidated by the comparison of their NMR and HRESIMS spectroscopic data with that of a structurally related compound...
- Nitric oxide production inhibitory activity of flavonoids contained in trunk exudates of Dalbergia sissoo
[作者:Shrestha, SP; Arnano, Y; Narukawa, Y; Takeda, T,期刊:Journal of natural products, 页码:98-101 , 文章类型: Article,,卷期:2008年71-1]
- Methanolic extracts of trunk exudates of Dalbergia sissoo yielded two new open-chain neoflavonoids (1, 2), a new flavonoid (3), a new flavanone (4), and 26 known compounds. Their structures were elucidated by detailed sp...
- Isolation of cytotoxic metabolites from targeted Peruvian amazonian medicinal plants
[作者:Aponte, JC; Vaisberg, AJ; Rojas, R; Caviedes, L; Lewis, WH; Lamas, G; Sarasara, C; Gilman, RH; Hammond, GB,期刊:Journal of natural products, 页码:102-105 , 文章类型: Article,,卷期:2008年71-1]
- The antiproliferative bioassay-guided fractionation of five Peruvian plants, Doliocarpus dentatus, Picramnia sellowii, Strychnos mitscherlichii, Iryanthera juruensis, and Croton alnifolius, led to the isolation and ident...
- Microbial transformation of isosteviol and bioactivities against the glucocorticoid/androgen response elements
[作者:Chang, SF; Yang, LM; Lo, CH; Liaw, JH; Wang, LH; Lin, SJ,期刊:Journal of natural products, 页码:87-92 , 文章类型: Article,,卷期:2008年71-1]
Preparative-scale fermentation of isosteviol (ent-16-oxobeyeran-19-oic acid) (1) with Mucor recurvatus MR 36, Absidia pseudocylindrospora ATCC 24169, and Aspergillus niger BCRC 32720 afforded nine known metabolites (2...
- Semisynthetic and biotransformation studies of (1S,2E,4S,6R,7E,11E)-2,7,11-cembratriene-4,6-diol
[作者:El Sayed, KA; Laphookhieo, S; Yousaf, M; Prestridge, JA; Shirode, AB; Wali, VB; Sylvester, PW,期刊:Journal of natural products, 页码:117-122 , 文章类型: Article,,卷期:2008年71-1]
- Tobacco-derived (1S,2E,4S,6R,7E,11E)-2,7,11-cembratriene-4,6-diol (1) and (1S,2E,4R,6R,7E,11E)-2,7,11-cembratriene-4,6-diol (2) were first shown to display potential antitumor-promoting activity in the mid-1980s. However...
- NF-kappa B-inhibiting naphthopyrones from the Fijian echinoderm Comanthus parvicirrus
[作者:Folmer, F; Harrison, WTA; Tabudravu, JN; Jaspars, M; Aalbersberg, W; Feussner, K; Wright, AD; Dicato, M; Diederich, M,期刊:Journal of natural products, 页码:106-111 , 文章类型: Article,,卷期:2008年71-1]
- The two naphthopyrones 6-methoxycomaparvin (1) and 6-methoxycomaparvin 5-methyl ether (2) were isolated from a bioactive methanol-soluble extract of the Fijian echinoderm Comanthus parvicirrus. Their structures were assi...
- Alkaloids from stems and leaves of Stemona japonica and their insecticidal activities
[作者:Tang, CP; Chen, T; Velten, R; Jeschke, P; Ebbinghaus-Kintscher, U; Geibel, S; Ye, Y,期刊:Journal of natural products, 页码:112-116 , 文章类型: Article,,卷期:2008年71-1]
- Five new alkaloids, 6 beta-hydroxystemofoline (1), 16-hydroxystemofoline (2), neostemofoline (3), protostemodiol (4), and 13-demethoxy-11(S*),12(R*)-dihydroprotostemonine (5), along with 10 known alkaloids, were isolated...
- Antileishmanial compounds from Cordia fragrantissima collected in Burma (Myanmar)
[作者:Mori, K; Kawano, M; Fuchino, H; Ooi, T; Satake, M; Agatsuma, Y; Kusumi, T; Sekita, S,期刊:Journal of natural products, 页码:18-21 , 文章类型: Article,,卷期:2008年71-1]
- A methanol extract of the wood of Cordia fragrantissima, collected in Burma (Myanmar), was found to exhibit significant activity against Leishmania major. Bioassay-guided fractionation of this extract using several chrom...
- Diarylheptanoids and a monoterpenoid from the rhizomes of Zingiber officinale: Antioxidant and cytoprotective properties
[作者:Tao, QF; Xu, Y; Lam, RYY; Schneider, B; Dou, H; Leung, PS; Shi, SY; Zhou, CX; Yang, LX; Zhang, RP; Xiao, YC; Wu, XM; Stockigt, J; Zeng, S; Cheng, CHK; Zhao, Y,期刊:Journal of natural products, 页码:12-17 , 文章类型: Article,,卷期:2008年71-1]
- Three new diarylheptanoids and one new monoterpenoid were isolated from the rhizomes of Zingiber officinale together with four known diarylheptanoids, 5-8. Their structures were elucidated mainly by spectroscopic methods...
- Symplocamide A, a potent cytotoxin and chymotrypsin inhibitor from the marine cyanobacterium Symploca sp.
[作者:Linington, RG; Edwards, DJ; Shuman, CF; McPhail, KL; Matainaho, T; Gerwick, WH,期刊:Journal of natural products, 页码:22-27 , 文章类型: Article,,卷期:2008年71-1]
- Investigation of a Symploca sp. from Papua New Guinea has led to the isolation of symplocamide A (1), a potent cancer cell cytotoxin, which also inhibits serine proteases with a 200-fold greater inhibition of chymotrypsi...
- Morphinane alkaloid dimers from Sinomenium acutum
[作者:Jin, HZ; Wang, XL; Wang, HB; Wang, YB; Lin, LP; Ding, J; Qin, GW,期刊:Journal of natural products, 页码:127-129 , 文章类型: Article,,卷期:2008年71-1]
- Two new morphinane alkaloid dimers, 2,2'-disinomenine (1) and 7',8'-dihydro-1,1'-disinomenine (2), and known 1, 1'-disinomenine (3), were isolated from ethanol extracts of stems of Sinomenium acutum: Their structures wer...
- Antineoplastic agents. 558. Ampelocissus sp cancer cell growth inhibitory constituents
[作者:Pettit, GR; Mukku, VJRV; Cragg, G; Herald, DL; Knight, JC; Herald, CL; Chapuis, JC,期刊:Journal of natural products, 页码:130-133 , 文章类型: Article,,卷期:2008年71-1]
- An investigation of the Phillippine Ampelocissus sp. roots for cancer cell growth inhibitory components led to the isolation of a new acetogenin characterized as 22-epicalamistrin (1) employing primarily 2D NMR and high-...
- Secondary metabolites of Cinnamosma madagascariensis and their alpha-glucosidase inhibitory properties
[作者:Harinantenaina, L; Matsunami, K; Otsuka, H; Kawahata, M; Yamaguchi, K; Asakawa, Y,期刊:Journal of natural products, 页码:123-126 , 文章类型: Article,,卷期:2008年71-1]
- Two new drimane-type sesquiterpenes, cinnamadin (1) and cinnamodial 11 alpha, 12 beta-dimethyl acetal (2), together with pereniporin B (3), ugandensolide (4), polygodial (5), capsicodendrin, cinnamodial (6), sitosterol, ...
- Bioactive triterpene saponins from the roots of Phytolacca americana
[作者:Wang, LY; Bai, LT; Nagasawa, T; Hasegawa, T; Yang, XY; Sakai, JI; Bai, YH; Kataoka, T; Oka, S; Hirose, K; Tomida, A; Tsuruo, T; Ando, M,期刊:Journal of natural products, 页码:35-40 , 文章类型: Article,,卷期:2008年71-1]
- Five new triterpene saponins named phytolaccasaponins N-1 (1), N-2 (2), N-3 (3) N-4 (4), and N-5 (5) were isolated from the roots of Phytolacca americana together with seven known triterpene saponins (6-12). The structur...
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