- Regulation of transcription factor E2F3a and its clinical relevance in ovarian cancer
[作者:Reimer, D; Hubalek, M; Kiefel, H; Riedle, S; Skvortsov, S; Erdel, M; Hofstetter, G; Concin, N; Fiegl, H; Muller-Holzner, E; Marth, C; Altevogt, P; Zeimet, AG,期刊:Oncogene, 页码:4038-4049 , 文章类型: Article,,卷期:2011年30-38]
- Recently we showed an integral epidermal growth factor receptor (EGFR)-E2F3a signaling path, in which E2F3a was found to be essential in EGFR-mediated proliferation in ovarian cancer cells. The present work evaluates the...
- The HTLV-1 Tax protein inhibits formation of stress granules by interacting with histone deacetylase 6
[作者:Legros, S; Boxus, M; Gatot, JS; Van Lint, C; Kruys, V; Kettmann, R; Twizere, JC; Dequiedt, F,期刊:Oncogene, 页码:4050-4062 , 文章类型: Article,,卷期:2011年30-38]
- Human T cell leukemia virus type-1 (HTLV-1) is the causative agent of a fatal adult T-cell leukemia. Through deregulation of multiple cellular signaling pathways the viral Tax protein has a pivotal role in T-cell transfo...
- Further activation of FLT3 mutants by FLT3 ligand
[作者:Zheng, R; Bailey, E; Nguyen, B; Yang, X; Piloto, O; Levis, M; Small, D,期刊:Oncogene, 页码:4004-4014 , 文章类型: Article,,卷期:2011年30-38]
- Somatic mutations of FLT3 involving internal tandem duplication (ITD) of the juxtamembrane domain or point mutations in the tyrosine kinase domain (TKD) appear to activate FLT3 in a FLT3 ligand (FL)-independent manner. T...
- Identification of AFAP1L1 as a prognostic marker for spindle cell sarcomas
[作者:Furu, M; Kajita, Y; Nagayama, S; Ishibe, T; Shima, Y; Nishijo, K; Uejima, D; Takahashi, R; Aoyama, T; Nakayama, T; Nakamura, T; Nakashima, Y; Ikegawa, M; Imoto, S; Katagiri, T; Nakamura, Y; Toguchida, J,期刊:Oncogene, 页码:4015-4025 , 文章类型: Article,,卷期:2011年30-38]
- Spindle cell sarcomas consist of tumors with different biological features, of which distant metastasis is the most ominous sign for a poor prognosis. However, metastasis is difficult to predict on the basis of current h...
- Role of SLC5A8, a plasma membrane transporter and a tumor suppressor, in the antitumor activity of dichloroacetate
[作者:Babu, E; Ramachandran, S; CoothanKandaswamy, V; Elangovan, S; Prasad, PD; Ganapathy, V; Thangaraju, M,期刊:Oncogene, 页码:4026-4037 , 文章类型: Article,,卷期:2011年30-38]
- There has been growing interest among the public and scientists in dichloroacetate (DCA) as a potential anticancer drug. Credible evidence exists for the antitumor activity of this compound, but high concentrations are n...
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