个性化文献订阅>文章检索

文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共71条记录   Straightforward Assembly of the Octahydroisoquinoline Core of Morphinan Alkaloids [作者：DUNET JULIE; LEBEUF RAPHAEL; BOSE GOPAL; ROBERT FREDERIC; LANDAIS YANNICK,期刊：Organic Letters, 页码：2178-2181 , 文章类型： Article，,卷期：2010年12-10] The octahydroisoquinoline core of morphinan was assembled starting from readily available arylcyclohexadienes. Three different approaches were developed, including a metal- and an acid-mediated Mannich type process and a... A Formal [4+4] Complementary Ambiphile Pairing Reaction: A New Cyclization Pathway for ortho-Quinone Methides [作者：SAMARAKOON THIWANKA B; HUR MOON Y; KURTZ RYAN D; HANSON PAUL R,期刊：Organic Letters, 页码：2182-2185 , 文章类型： Article，,卷期：2010年12-10] A formal, one-pot [4 + 4] cyclization pathway for the generation of eight-membered sultams via in situ generation of an ortho-quinone methide (o-QM) is reported. The pairing of ambiphilic synthons in a complementary fash... Highly Efficient Diastereoselective Reduction of alpha-Fluoroimines [作者：MALAMAKAL ROY M; HESS WHITNEY R; DAVIS TODD A,期刊：Organic Letters, 页码：2186-2189 , 文章类型： Article，,卷期：2010年12-10] A highly selective reduction of alpha-fluoroimines to the corresponding beta-fluoroamines has been developed utilizing trichlorosilane as the reductant. The key aspect of this reaction is the ability of fluorine and nitr... Efficient Solid-Phase Chemical Synthesis of 5 '-Triphosphates of DNA, RNA, and their Analogues [作者：ZLATEV IVAN; LAVERGNE THOMAS; DEBART FRANCOISE; VASSEUR JEANJACQUES; MANOHARAN MUTHIAH; MORVAN FRANCOIS,期刊：Organic Letters, 页码：2190-2193 , 文章类型： Article，,卷期：2010年12-10] A robust, reproducible, and scalable method for the solid-phase synthesis of 5'-triphosphates of DNA, RNA, and their chemically modified analogues using 5'-H-phosphonate intermediates is described. T-Triphosphates of oli... Cyanines as New Fluorescent Probes for DNA Detection and Two-Photon Excited Bioimaging [作者：FENG XIN JIANG; WU PO LAM; BOLZE FREDERIC; LEUNG HEIDI W C; LI KING FAI; MAK NAI KI; KWONG DANIEL W J; NICOUD JEANFRANCOIS; CHEAH KOK WAI; WONG MAN SHING,期刊：Organic Letters, 页码：2194-2197 , 文章类型： Article，,卷期：2010年12-10] A series of cyanine fluorophores based on fused aromatics as an electron donor for DNA sensing and two-photon bioimaging were synthesized, among which the carbazole-based biscyanine exhibits high sensitivity and efficien... Combined Directed ortho Metalation-Halogen Dance (HD) Synthetic Strategies. HD-Anionic ortho Fries Rearrangement and Double HD Sequences [作者：MILLER RICARDA E; RANTANEN TONI; OGILVIE KEVIN A; GROTH ULRICH; SNIECKUS VICTOR,期刊：Organic Letters, 页码：2198-2201 , 文章类型： Article，,卷期：2010年12-10] A general and efficient directed ortho metalation (DoM)-halogen dance (HD)-electrophile quench sequence for the synthesis of trisubstituted pyridyl O-carbamates is described. A second HD sequence furnishes highly functio... Highly Selective Visual Detection of Cu(II) Utilizing Intramolecular Hydrogen Bond-Stabilized Merocyanine in Aqueous Buffer Solution [作者：GUO ZHAOQI; CHEN WEIQIANG; DUAN XUANMING,期刊：Organic Letters, 页码：2202-2205 , 文章类型： Article，,卷期：2010年12-10] A Cu2+-specific colorimetric sensor 1, which is stabilized by an intramolecular hydrogen bonding, was designed and developed. The color of 1 changes from purple to blue on addition of 1.0 mu M Cu2+ in aqueous buffer solu... Chemoenzymatic Synthesis of Carbasugars (+)-Pericosines A-C from Diverse Aromatic cis-Dihydrodiol Precursors [作者：BOYD DEREK R; SHARMA NARAIN D; ACARU CARMEN A; MALONE JOHN F; ODOWD COLIN R; ALLEN CHRISTOPHER C R; STEVENSON PAUL J,期刊：Organic Letters, 页码：2206-2209 , 文章类型： Article，,卷期：2010年12-10] cis-Dihydrocatechols, derived from biological cis-dihydroxylation of methyl benzoate, iodobenzene and benzonitrile, using the microorganism Pseudomonas putida UV4, were converted into pericosines A, C, and B, respectivel... KHMDS Enhanced SmI2-Mediated Reformatsky Type alpha-Cyanation [作者：ANKNER TOBIAS; FRIDENSAXIN MARIA; PEMBERTON NILS; SEIFERT TINA; GROTLI MORTEN; LUTHMAN KRISTINA; HILMERSSON GORAN,期刊：Organic Letters, 页码：2210-2213 , 文章类型： Article，,卷期：2010年12-10] A novel combination of SmI2, KHMDS, and TsCN can be utilized to introduce a cyano group into structurally diverse and highly sensitive 2-alkyl-chroman-4-ones. Subsequent oxidation allows the formed 2-alkyl-3-cyanochromon... N,N '-Dioxide-Cu(OTf)(2) Complex Catalyzed Highly Enantioselective Amination Reaction of N-Acetyl Enamide [作者：CHANG LU; KUANG YULONG; QIN BO; ZHOU XIN; LIU XIAOHUA; LIN LILI; FENG XIAOMING,期刊：Organic Letters, 页码：2214-2217 , 文章类型： Article，,卷期：2010年12-10] The N,N'-dioxide-Cu(OTf)(2) complexes were applied in,the asymmetric amination reaction of N-acetyl enamides with dialkyl azodicarboxylate, giving the corresponding products in good yields with high enantioselectivities ... Direct Assignment of the Relative Configuration in 1,3,n-Methyl-Branched Carbon Chains by H-1 NMR Spectroscopy [作者：SCHMIDT YVONNE; BREIT BERNHARD,期刊：Organic Letters, 页码：2218-2221 , 文章类型： Article，,卷期：2010年12-10] On the basis of the assignment of methylene proton signals in H-1 NMR and determination of the chemical shift difference (Delta delta), the relative configuration of 1,3,n-methyl-branched deoxypropionates can be determin... Synthesis of (-)-(S,S)-clemastine by Invertive N -> C Aryl Migration in a Lithiated Carbamate [作者：FOURNIER ANNE M; BROWN ROBERT A; FARNABY WILLIAM; MIYATAKEONDOZABAL HIDEKI; CLAYDEN JONATHAN,期刊：Organic Letters, 页码：2222-2225 , 文章类型： Article，,卷期：2010年12-10] The first enantioselective synthesis of the antihistamine agent clemastine, as its (S,S)-stereoisomer, has been achieved by ether formation between a proline-derived chloroethylpyrrolidine and an enantiomerically enriche... Intriguing Substrate Tolerance of Epoxide Hydrolase Lsd19 Involved in Biosynthesis of the Ionophore Antibiotic Lasalocid A [作者：MATSUURA YUSUKE; SHICHIJO YOSHIHIRO; MINAMI ATSUSHI; MIGITA AKIRA; OGURI HIROKI; WATANABE MAMI; TOKIWANO TETSUO; WATANABE KENJI; OIKAWA HIDEAKI,期刊：Organic Letters, 页码：2226-2229 , 文章类型： Article，,卷期：2010年12-10] Recently, we reported that the epoxide hydrolase Lsd19, the first enzyme shown to catalyze epoxide-opening cascades, can catalyze the conversion of a putative bisepoxide intermediate to polyether antibiotic lasalocid, wh... A Novel Diastereoselective Multicomponent Cascade Reaction [作者：KRIIS KADRI; AUSMEES KERTI; PEHK TONIS; LOPP MARGUS; KANGER TONIS,期刊：Organic Letters, 页码：2230-2233 , 文章类型： Article，,卷期：2010年12-10] A novel multicomponent cascade reaction led to the formation of a strained 3-azabicyclo[3.2.0]heptane derivative 4. The unstable ester 4 was reduced in a one-pot procedure to a stable alcohol 6. The formation of the bicy... Synthesis of 2H-Indazoles by the [3+2] Cycloaddition of Arynes and Sydnones [作者：WU CHUNRUI; FANG YUESI; LAROCK RICHARD C; SHI FENG,期刊：Organic Letters, 页码：2234-2237 , 文章类型： Article，,卷期：2010年12-10] A rapid and efficient synthesis of 2H-indazoles has been developed, which involves the [3 + 2] dipolar cycloaddition of arynes and sydnones. The process proceeds under mild reaction conditions in good to excellent yields... Electrophilicities of alpha-Chlorinating Agents Used in Organocatalysis [作者：DUAN XINHUA; MAYR HERBERT,期刊：Organic Letters, 页码：2238-2241 , 文章类型： Article，,卷期：2010年12-10] Kinetics of the reactions of the chlorinating agents 1a-c with pi-nucleophiles have been studied to include these compounds in our comprehensive electrophilicity scale.