- Convenient mild and selective hydrophosphination of functionalized alkenes: access to P,O and P,S derivatives.
[作者:Join, Benoit;Lohier, Jean-Francois;Delacroix, Olivier;Gaumont, Annie-Claude;,期刊:Synthesis, 页码:3121-3125 , 文章类型: 研究论文,,卷期:2008年-19]
- The synthesis of new functionalized phosphines is carried out through the easy and atom economic hydrophosphination reaction of functionalized alkenes such as vinyl ethers and vinyl thioethers. The reactions occur under...
- Synthesis of substituted imidazo[1,2-h][1,7]naphthyridines as H+/K+-ATPase inhibiting drug precursors via directed ortho-metalation of imidazo[1,2-a]pyridines.
[作者:Senn-Bilfinger, Joerg;Kohl, Bernhard;Rainer, Georg;Buhr, Wilm;Holst, Hans Christof;Zimmermann, Peter Jan;,期刊:Synthesis, 页码:3065-3070 , 文章类型: 研究论文,,卷期:2008年-19]
- Selective directed ortho-metalation (DOM) of 2,3-dimethyl-8-(pivaloylamino)imidazo[1,2-a]pyridine in the 7-position was achieved with tert-butyllithium. Subsequent reaction of the lithiated deriv. with tributylchlorosta...
- Carbohydrate-based spiro-1,3-oxazolidine-2-thiones: stereoselective approaches using aziridines and epoxides.
[作者:Tardy, Sebastien;Vicente, Joana Lobo;Tatibouet, Arnaud;Dujardin, Gilles;Rollin, Patrick;,期刊:Synthesis, 页码:3108-3120 , 文章类型: 研究论文,,卷期:2008年-19]
- D-Glucose and D-fructose have been used as starting materials to prep. spiro-1,3-oxazolidine-2-thiones anchored on the third position of both carbohydrates. Following different approaches and depending on the carbohydra...
- Synthesis of cyclitols via cyclopropanation/palladium-catalyzed ring opening.
[作者:Shan, Mingde;O'Doherty, George A.;,期刊:Synthesis, 页码:3171-3179 , 文章类型: 研究论文,,卷期:2008年-19]
- The stereoselective syntheses of three cyclitols, 5a-carba-a-D-rhamnopyranose, 5a-carba-b-D-digitoxopyranose, and 5a-carba-a-L-rhamnopyranose, have been achieved. The routes rely upon a Simmons-Smith cyclopropanation an...
- Preparation of the maleic anhydride nucleus from dichloro g-lactams: focus on the role of the N-substituent in the functional rearrangement and in the hydrolytic steps.
[作者:Ghelfi, Franco;Pattarozzi, Mariella;Roncaglia, Fabrizio;Parsons, Andrew F.;Felluga, Fulvia;Pagnoni, Ugo M.;Valentin, Ennio;Mucci, Adele;Bellesia, Franco;,期刊:Synthesis, 页码:3131-3141 , 文章类型: 研究论文,,卷期:2008年-19]
- comparison of various N-substituents in the functional rearrangement step. The 2-pyridyl group proved to be the most appropriate N-substituent for the hydrolysis of the 5-methoxy-1,5-dihydro-2H-pyrrol-2-one intermediate...
- The determinative influence of the O6-(diphenylcarbamoyl) group on the exocyclic nitrogen benzylation in 2-amino-6-oxopurine derivatives.
[作者:Madre, Marina;Petrova, Marina;Belyakov, Sergey;,期刊:Synthesis, 页码:3053-3060 , 文章类型: 研究论文,,卷期:2008年-19]
- A series of novel 2-(benzylamino)-6-oxopurine derivs. was synthesized by arylalkylation of the corresponding 2-(acetylamino)-6-(diphenylcarbamoyloxy)purines. E.g., 2-(benzylamino)-6-oxopurines I [R = CH2Ph, CH2C6H4-2-F,...
- Cu(OTf)2-catalyzed isomerization of 7-oxabicyclic alkenes: a practical route to the synthesis of 1-naphthol derivatives.
[作者:Peng, Fangzhi;Fan, Baomin;Shao, Zhihui;Pu, Xuewei;Li, Penghui;Zhang, Hongbin;,期刊:Synthesis, 页码:3043-3046 , 文章类型: 研究论文,,卷期:2008年-19]
- Lewis acid catalyzed isomerization of 7-oxabicyclic alkenes into 1-naphthol derivs., e.g., I, in high yields (87-98%) under mild reaction conditions has been developed. The mechanism of this reaction is briefly postulat...
- Synthesis of substituted monohalobenzenes via ortho-selective cross-coupling of dihalobenzenes with electron-donating ortho-directing groups.
[作者:Ishikawa, Shunpei;Manabe, Kei;,期刊:Synthesis, 页码:3180-3182 , 文章类型: 研究论文,,卷期:2008年-19]
- Dihalobenzenes that possess directing groups such as OH, CH2OH, NH2, NHAc, or NHBoc were subjected to ortho-selective cross-coupling with Grignard reagents in the presence of palladium-based catalysts to give the corresp...
- A new synthesis of bis-enaminones via acylation of ketones.
[作者:Buehrdel, Gunther;Beckert, Rainer;Petrlikova, Eva;Herzigova, Petra;Klimesova, Vera;Fleischhauer, Jan;Goerls, Helmar;,期刊:Synthesis, 页码:3071-3080 , 文章类型: 研究论文,,卷期:2008年-19]
- A short and efficient synthesis for a series of 1,6-diaryl-3,4-diarylaminohexa-2,4-diene-1,6-diones was developed. Based on the acylation-prototropism sequence during the reaction of various aryl Me ketones with bis-imid...
- 1,1,1,3,3,3-Hexafluoroisopropanol: a recyclable organocatalyst for N-Boc protection of amines.
[作者:Heydari, Akbar;Khaksar, Samad;Tajbakhsh, Mahmood;,期刊:Synthesis, 页码:3126-3130 , 文章类型: 研究论文,,卷期:2008年-19]
- A simple and efficient protocol for the chemoselective mono-N-Boc protection of various structurally diverse amines with di-tert-Bu dicarbonate using 1,1,1,3,3,3-hexafluoroisopropanol (HFIP) as solvent and catalyst is de...
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