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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共10条记录   P-Selectin Antagonism in Inflammatory Disease [作者：Woollard, KJ; Chin-Dusting, J,期刊：Current Pharmaceutical Design, 页码：4113-4118 , 文章类型： Review，,卷期：2010年16-37] Inflammation plays a fundamental role in many chronic diseases, including atherosclerosis associated cardiovascular disease. Adhesion of immune cells plays a critical role in the inflammatory response and indeed the path... Evolving Concepts Concerning Cardiac beta-Adrenoceptor Function in Heart Failure [作者：Black, J; Fitzgerald, D,期刊：Current Pharmaceutical Design, 页码：4148-4158 , 文章类型： Review，,卷期：2010年16-37] This review describes the clinical application of beta-adrenergic blocking drugs over time in patients with congestive heart failure. The different pharmacological properties of these drugs in relation to clinical outcom... HDL Therapy: Two Kinds of Right? [作者：Murphy, AJ; Remaley, AT; Sviridov, D,期刊：Current Pharmaceutical Design, 页码：4134-4147 , 文章类型： Review，,卷期：2010年16-37] Cardiovascular disease remains the leading cause of morbidity and mortality globally. The disease is largely controlled with interventions managing atherogenic lipids including LDL and triglycerides. However a number of ... C-type Natriuretic Peptide (CNP): Cardiovascular Roles and Potential as a Therapeutic Target [作者：Lumsden, NG; Khambata, RS; Hobbs, AJ,期刊：Current Pharmaceutical Design, 页码：4080-4088 , 文章类型： Review，,卷期：2010年16-37] Natriuretic peptides play a fundamental role in cardiovascular homeostasis by modulation of fluid and electrolyte balance and vascular tone. C-type natriuretic peptide (CNP) represents the paracrine element of the natriu... Cytoprotection by Natural and Synthetic Polyphenols in the Heart: Novel Mechanisms and Perspectives [作者：Jiang, F; Chang, CWT; Dusting, GJ,期刊：Current Pharmaceutical Design, 页码：4103-4112 , 文章类型： Review，,卷期：2010年16-37] While many naturally occurring polyphenols have been shown to have therapeutic benefits against myocardial injury following ischemia-reperfusion in various experimental models, our studies have demonstrated that syntheti... Ectopic ATP Synthase in Endothelial Cells: A Novel Cardiovascular Therapeutic Target [作者：Fu, Y; Zhu, Y,期刊：Current Pharmaceutical Design, 页码：4074-4079 , 文章类型： Review，,卷期：2010年16-37] Adenosine triphosphate (ATP) synthase produces ATP in cells and is found on the inner membrane of mitochondria or the cell plasma membrane (ectopic ATP synthase). Here, we summarize the functions of ectopic ATP synthase ... Editorial: New Perspectives in Cardiovascular Medicine [作者：Chin-Dusting, JPF,期刊：Current Pharmaceutical Design, 页码：4072-+ , 文章类型： Editorial Material，,卷期：2010年16-37] Targeting the Platelet Integrin GPIIb/IIIa [作者：Hagemeyer, CE; Peter, K,期刊：Current Pharmaceutical Design, 页码：4119-4133 , 文章类型： Review，,卷期：2010年16-37] The platelet integrin GPIIb/IIIa plays an essential role in thrombus formation through interactions with adhesive ligands and has emerged as a primary target for the development of anti-thrombotic agents. Receptor activa... The Biology and Therapeutic Potential of the DDAH/ADMA Pathway [作者：Arrigoni, F; Ahmetaj, B; Leiper, J,期刊：Current Pharmaceutical Design, 页码：4089-4102 , 文章类型： Review，,卷期：2010年16-37] Asymmetric dimethylarginine (ADMA) is an endogenously produced molecule that inhibits nitric oxide synthase and consequently may have adverse effects on physiology, in particular in the cardiovascular system. This review... Untitled [作者：de la Torre-Ruiz, MA,期刊：Current Pharmaceutical Design, 页码：4072-4073 , 文章类型： Editorial Material，,卷期：2010年16-37]