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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共9条记录   Adipose Tissue as a Target of HIV-1 Antiretroviral Drugs. Potential Consequences on Metabolic Regulations [作者：Caron-Debarle, M; Boccara, F; Lagathu, C; Antoine, B; Cervera, P; Bastard, JP; Vigouroux, C; Capeau, J,期刊：Current Pharmaceutical Design, 页码：3352-3360 , 文章类型： Review，,卷期：2010年16-30] Adipose tissue redistribution occurred at first in HIV-infected patients about 15 years ago after initiation of combination antiretroviral treatment (ART) and the responsibility of drugs was rapidly considered. This lipo... Impact of Mitochondrial Toxicity of HIV-1 Antiretroviral Drugs on Lipodystrophy and Metabolic Dysregulation [作者：Feeney, ER; Mallon, PWG,期刊：Current Pharmaceutical Design, 页码：3339-3351 , 文章类型： Review，,卷期：2010年16-30] Nucleoside reverse transcriptase inhibitors (NRTIs) are components of most current antiretroviral (ARV) regimens. Side effects arising from mitochondrial toxicity (MtT) induced by these drugs is a common reason why patie... Lipotoxicity on the Basis of Metabolic Syndrome and Lipodystrophy in HIV-1-Infected Patients Under Antiretroviral Treatment [作者：Giralt, M; Diaz-Delfin, J; Gallego-Escuredo, JM; Villarroya, J; Domingo, P; Villarroya, F,期刊：Current Pharmaceutical Design, 页码：3372-3378 , 文章类型： Review，,卷期：2010年16-30] The development of efficacious antiretroviral drugs that minimize adverse effects is a current challenge in HIV-1 therapy. Metabolic alterations reminiscent of the metabolic syndrome and overt lipodystrophy appear often ... Combination of Fenofibrate with Non-Statin Drug Regimens [作者：Agouridis, AP; Filippatos, TD; Derdemezis, CS; Mikhailidis, DP; Elisaf, MS,期刊：Current Pharmaceutical Design, 页码：3401-3416 , 文章类型： Review，,卷期：2010年16-30] Objective: We present the available data on the effects of combined therapy of fenofibrate with drugs affecting lipid metabolism other than statins. Methods: We consider studies evaluating the effects of combined therapy... Concepts for Biologically Active Peptides [作者：Kastin, AJ; Pan, WH,期刊：Current Pharmaceutical Design, 页码：3390-3400 , 文章类型： Review，,卷期：2010年16-30] Here we review a unique aspect of CNS research on biologically active peptides that started against a background of prevalent dogmas but ended by exerting considerable influence on the field. During the course of refutin... Contribution of Inflammation to Fat Redistribution and Metabolic Disturbances in HIV-1 Infected Patients [作者：Stankov, MV; Behrens, GMN,期刊：Current Pharmaceutical Design, 页码：3361-3371 , 文章类型： Review，,卷期：2010年16-30] Antiretroviral therapy (ART) has significantly reduced the morbidity and mortality of patients infected with the human immunodeficiency virus 1 (HIV-1). In a significant number of patients, ART is associated with fat red... Pharmacogenetics of the Metabolic Disturbances and Atherosclerosis Associated with Antiretroviral Therapy in HIV-Infected Patients [作者：Veloso, S; Peraire, J; Vilades, C; Lopez-Dupla, M; Escote, X; Olona, M; Garcia-Pardo, G; Gomez-Bertomeu, F; Soriano, A; Sirvent, JJ; Vidal, F,期刊：Current Pharmaceutical Design, 页码：3379-3389 , 文章类型： Review，,卷期：2010年16-30] The availability of highly active antiretroviral therapy has markedly improved the survival rate and quality of life in patients infected with HIV. At present, however, there is still no cure for HIV and those undergoing... Targets of Metabolic Toxicity of HIV Antiretroviral Drugs: The Multiple Roads to Lipodystrophy and Metabolic Syndrome [作者：Domingo, P; Villarroya, F,期刊：Current Pharmaceutical Design, 页码：3337-3338 , 文章类型： Editorial Material，,卷期：2010年16-30] Vitamin D and Metabolic Syndrome: Is There a Link? [作者：Florentin, M; Elisaf, MS; Mikhailidis, DP; Liberopoulos, EN,期刊：Current Pharmaceutical Design, 页码：3417-3434 , 文章类型： Review，,卷期：2010年16-30] In addition to bone homeostasis, vitamin D is involved in the physiological functions of several tissues and its insufficiency may contribute to various disorders. Vitamin D status seems to be associated with each of the...