- An inactivating CYLD mutation promotes skin tumor progression by conferring enhanced proliferative, survival and angiogenic properties to epidermal cancer cells
[作者：Alameda, JP; Moreno-Maldonado, R; Navarro, M; Bravo, A; Ramirez, A; Page, A; Jorcano, JL; Fernandez-Acenero, MJ; Casanova, ML,期刊：Oncogene, 页码：6522-6532 , 文章类型： Article，,卷期：2010年29-50]
- In this study, we demonstrate that the expression in tumorigenic epidermal cells of a catalytically inactive form of CYLD (CYLDC/S) that mimics the identified mutations of cyld in human tumors and competes with the endog...
- The role of fibroblast Tiam1 in tumor cell invasion and metastasis
[作者：Xu, K; Rajagopal, S; Klebba, I; Dong, S; Ji, Y; Liu, J; Kuperwasser, C; Garlick, JA; Naber, SP; Buchsbaum, RJ,期刊：Oncogene, 页码：6533-6542 , 文章类型： Article，,卷期：2010年29-50]
- The co-evolution of tumors and their microenvironment involves bidirectional communication between tumor cells and tumor-associated stroma. Various cell types are present in tumor-associated stroma, of which fibroblasts ...
- Rheb activates AMPK and reduces p27Kip1 levels in Tsc2-null cells via mTORC1-independent mechanisms: implications for cell proliferation and tumorigenesis
[作者：Lacher, MD; Pincheira, R; Zhu, Z; Camoretti-Mercado, B; Matli, M; Warren, RS; Castro, AF,期刊：Oncogene, 页码：6543-6556 , 文章类型： Article，,卷期：2010年29-50]
- Tuberous sclerosis complex (TSC) is an autosomally inherited disorder that causes tumors to form in many organs. It is frequently caused by inactivating mutations in the TSC2 tumor-suppressor gene. TSC2 negatively regula...
- Exogenous cell-permeable C6 ceramide sensitizes multiple cancer cell lines to Doxorubicin-induced apoptosis by promoting AMPK activation and mTORC1 inhibition
[作者：Ji, C; Yang, B; Yang, YL; He, SH; Miao, DS; He, L; Bi, ZG,期刊：Oncogene, 页码：6557-6568 , 文章类型： Article，,卷期：2010年29-50]
- New chemotherapy-enhancing strategies are needed for better cancer therapy. Previous studies suggest that exogenous cell-permeable C6 ceramide may be a useful adjunct to the anti-tumor effects of chemotherapeutic agents ...
- miR-145-dependent targeting of Junctional Adhesion Molecule A and modulation of fascin expression are associated with reduced breast cancer cell motility and invasiveness
[作者：Gotte, M; Mohr, C; Koo, CY; Stock, C; Vaske, AK; Viola, M; Ibrahim, SA; Peddibhotla, S; Teng, YHF; Low, JY; Ebnet, K; Kiesel, L; Yip, GW,期刊：Oncogene, 页码：6569-6580 , 文章类型： Article，,卷期：2010年29-50]
- Micro RNAs are small non-coding RNAs, which regulate fundamental cellular and developmental processes at the transcriptional and translational level. In breast cancer, miR-145 expression is downregulated compared with he...
- Inhibition of beta 1 integrin and IL-3R beta common subunit interaction hinders tumour angiogenesis
[作者：Uberti, B; Dentelli, P; Rosso, A; Defilippi, P; Brizzi, MF,期刊：Oncogene, 页码：6581-6590 , 文章类型： Article，,卷期：2010年29-50]
- Integrin/cytokine receptor interaction provides permissive signals leading to neoangiogenesis, and integrins are crucial for differentiation of endothelial progenitor cells (EPCs). It is known that the inflammatory inter...
- The immune response to sporadic colorectal cancer in a novel mouse model
[作者：Czeh, M; Loddenkemper, C; Shalapour, S; Schon, C; Robine, S; Goldscheid, E; Stein, H; Schuler, T; Willimsky, G; Blankenstein, T,期刊：Oncogene, 页码：6591-6602 , 文章类型： Article，,卷期：2010年29-50]
- Current mouse models do not reflect the sporadic nature of colon cancer and do not allow the analysis of antitumor immune response because of the lack of known tumor-specific antigens. Two transgenic mouse models with sp...
- Redox-dependent Brca1 transcriptional regulation by an NADH-sensor CtBP1
[作者：Deng, Y; Liu, J; Han, G; Lu, SL; Wang, SY; Malkoski, S; Tan, AC; Deng, C; Wang, XJ; Zhang, Q,期刊：Oncogene, 页码：6603-6608 , 文章类型： Article，,卷期：2010年29-50]
- C-terminal binding protein 1 (CtBP1) is a transcriptional co-repressor and metabolic sensory protein, which often represses tumor suppressor genes. Hence, we sought to determine if CtBP1 affects expression of the tumor s...
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