- Tumor-specific Cytotoxicity and Type of Cell Death Induced by Benzo[b]cyclohept[e][1,4]oxazine and 2-Aminotropone Derivatives
[作者:Narita, T; Suga, A; Kobayashi, M; Hashimoto, K; Sakagami, H; Motohashi, N; Kurihara, T; Wakabayashi, H,期刊:Anticancer Research, 页码:1123-1130 , 文章类型: Article,,卷期:2009年29-4]
- A total of twenty benzo[b]cyclohept[e] [1,4]oxazines and their S-analogs, and 2-aminotropone derivatives were investigated for their cytotoxicity against three human normal cells and four tumor cell lines. These compound...
- Apoptosis-related Factors (TRAIL, DR4, DR5, DcR1, DcR2, Apoptotic Cells) and Proliferative Activity in Ameloblastomas
[作者:Rizzardi, C; Leocata, P; Ventura, L; Zweyer, M; Brollo, A; Schneider, M; Melato, M,期刊:Anticancer Research, 页码:1137-1142 , 文章类型: Article,,卷期:2009年29-4]
- Background: Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is a recently identified death factor that acts as a potent apoptosis inducer in ameloblastomas. Materials and Methods: The expression of TRAIL ...
- Effects of Cepharanthine Alone and in Combination with Fluoropyrimidine Anticancer Agent, S-1, on Tumor Growth of Human Oral Squamous Cell Carcinoma Xenografts in Nude Mice
[作者:Harada, K; Ferdous, T; Itashiki, Y; Takii, M; Mano, T; Mori, Y; Ueyama, Y,期刊:Anticancer Research, 页码:1263-1270 , 文章类型: Article,,卷期:2009年29-4]
- Background: Chemotherapy has shown little antitumor activity against advanced oral squamous cell carcinoma (OSCC) patients. Therefore, there is an urgent need to develop more effective therapeutic methods for patients wi...
- Association of GNB4 Intron-1 Haplotypes with Survival in Patients with UICC Stage III and IV Colorectal Carcinoma
[作者:Riemann, K; Struwe, H; Alakus, H; Obermaier, B; Schmitz, KJ; Schmid, KW; Siffert, W,期刊:Anticancer Research, 页码:1271-1274 , 文章类型: Article,,卷期:2009年29-4]
- Background: Polymorphisms in genes encoding subunits of heterotrimeric G proteins have been repeatedly associated with the course of cancer. As previously shown, intron 1 of GNB4 harbours distinct haplotype blocks and bl...
- Rapamycin Effects on mTOR Signaling in Benign, Premalignant and Malignant Human Breast Epithelial Cells
[作者:Kim, SH; Zukowski, K; Novak, RF,期刊:Anticancer Research, 页码:1143-1150 , 文章类型: Article,,卷期:2009年29-4]
- Rapamycin, an inhibitor of mTOR, is in clinical trials for treatment of cancer. Rapamycin resistance has been reported in human breast epithelial tumor cells. Rapamycin effects on mTOR signaling and resistance were exami...
- Significant Association of Ku80 Single Nucleotide Polymorphisms with Bladder Cancer Susceptibility in Taiwan
[作者:Chang, CH; Chiu, CF; Liang, SY; Wu, HC; Chang, CL; Tsai, CW; Wang, HC; Lee, HZ; Bau, DT,期刊:Anticancer Research, 页码:1275-1279 , 文章类型: Article,,卷期:2009年29-4]
- The aim of the present study was to evaluate the association between the polymorphisms of the Ku80 DNA repair gene, which plays an important role in maintaining genome stability, and the risk of bladder cancer in Central...
- Cell Growth Stimulation by CRASH, an Asparaginase-like Protein Overexpressed in Human Tumors and Metastatic Breast Cancers
[作者:Weidle, UH; Evtimova, V; Alberti, S; Guerra, E; Fersis, N; Kaul, S,期刊:Anticancer Research, 页码:951-963 , 文章类型: Article,,卷期:2009年29-4]
- The gene encoding CRASH, a human asparaginase-like protein, has been cloned and its transcriptional activation has been detected in gynecologic cancers. To define the expression of CRASH in human tumors and its possible ...
- Overexpression of Cap43 is Associated with Malignant Status of Esophageal Cancer
[作者:Sohda, M; Mochida, Y; Kato, H; Miyazaki, T; Nakajima, M; Fukuchi, M; Manda, R; Fukai, Y; Masuda, N; On, M; Kuwan, M; Kuwano, H,期刊:Anticancer Research, 页码:965-970 , 文章类型: Article,,卷期:2009年29-4]
- Cap43 protein has been proven to be upregulated by nickel compounds or hypoxic stress, often during cell differentiation or cell growth art-est. However, the function of this gene remains unknown. Although, several studi...
- Vessel Dilator and Kaliuretic Peptide Inhibit Ras in Human Prostate Cancer Cells
[作者:Sun, Y; Eichelbaum, EJ; Skelton, WP; Lenz, A; Wang, H; Vesely, DL,期刊:Anticancer Research, 页码:971-975 , 文章类型: Article,,卷期:2009年29-4]
- Background: Vessel dilator and kaliuretic peptide have anticancer effects in human prostate adenocarcinomas. Materials and Methods: The effects of vessel dilator, kaliuretic peptide and cyclic GMP on Ras were examined in...
- Increased Human Telomerase Reverse Transcriptase (hTERT) mRNA Expression but not Telomerase Activity is Related to Survival in Curatively Resected Non-small Cell Lung Cancer
[作者:Metzger, R; Vallbohmer, D; Muller-Tidow, C; Higashi, H; Bollschweiler, E; Warnecke-Eberz, U; Brabender, J; Baldus, SE; Xi, H; Berdel, WE; Serve, H; Hoelscher, AH; Schneider, PM,期刊:Anticancer Research, 页码:1157-1162 , 文章类型: Article,,卷期:2009年29-4]
- Background: The purpose of this study was to evaluate the significance of human telomerase reverse transcriptase (hTERT) mRNA expression and telomerase activity, as prognostic markers in non-small cell lung cancer (NSCLC...
- The Role of the Homeobox Genes BFT and CDX2 in the Pathogenesis of Non-small Cell Lung Cancer
[作者:Grimminger, P; Ling, FC; Neiss, S; Vallbohmer, D; Lurje, G; Schneider, PM; Holscher, AH; Metzger, R; Brabender, J,期刊:Anticancer Research, 页码:1281-1286 , 文章类型: Article,,卷期:2009年29-4]
- Background: The role of the homeobox genes Backfoot (BFT) and caudal-related Homeobox 2 (CDX2) in the pathogenesis of non-small cell lung cancer (NSCLC) is unclear. The goal of this study was to investigate the mRNA expr...
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