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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共6条记录   Isolation, biology and chemistry of the disorazoles: new anti-cancer macrodiolides [作者：Hopkins, CD; Wipf, P,期刊：Natural Product Reports , 页码：585-601 , 文章类型： Review，,卷期：2009年26-5] The disorazoles comprise a family of 29 closely related macrocyclic polyketides isolated in 1994 from the fermentation broth of the gliding myxobacterium Sorangium cellulosum. Disorazoles A(1), E and C-1 have shown excep... Recent advances in the chemistry, biosynthesis and pharmacology of rapamycin analogs [作者：Graziani, EI,期刊：Natural Product Reports , 页码：602-609 , 文章类型： Review，,卷期：2009年26-5] In the period 1998 to 2003, a number of reviews have appeared evaluating the potential of rapamycin and other immunophilin ligands as therapies for cancer, organ transplantation, restenosis prevention, autoimmune disorde... Design of biologically active heparan sulfate and heparin using an enzyme-based approach [作者：Peterson, S; Frick, A; Liu, J,期刊：Natural Product Reports , 页码：610-627 , 文章类型： Review，,卷期：2009年26-5] Heparan sulfate (HS) is a highly sulfated polysaccharide that plays essential physiological and pathophysiological roles. Heparin, a special form of HS, is a commonly used anticoagulant drug. The biosynthesis of HS invol... Antitumor compounds from actinomycetes: from gene clusters to new derivatives by combinatorial biosynthesis [作者：Olano, C; Mendez, C; Salas, JA,期刊：Natural Product Reports , 页码：628-660 , 文章类型： Review，,卷期：2009年26-5] Antitumor compounds produced by actinomycetes and novel derivatives generated by combinatorial biosynthesis are reviewed (with 318 references cited). The different structural groups for which the relevant gene clusters h... Synthetic efforts toward cyathane diterpenoid natural products [作者：Enquist, JA; Stoltz, BM,期刊：Natural Product Reports , 页码：661-680 , 文章类型： Review，,卷期：2009年26-5] An overview of synthetic efforts toward cyathane diterpenoid natural products from the year 2000 to present is provided. The emphasis of this review is the various ring-constructing and stereoforming strategies employed ... Diterpenes from gorgonian corals [作者：Berrue, F; Kerr, RG,期刊：Natural Product Reports , 页码：681-710 , 文章类型： Review，,卷期：2009年26-5] Gorgonian corals continue to provide a wealth of novel structures, many of which exhibit potentially useful biological activity. Notably, the families Briareidae, Gorgoniidae and Plexauridae have been demonstrated to con...