- Exposure to Retinoic Acid in the Neonatal but Not Adult Mouse Results in Synchronous Spermatogenesis
[作者:Snyder, EM; Davis, JC; Zhou, Q; Evanoff, R; Griswold, MD,期刊:Biology of Reproduction, 页码:886-893 , 文章类型: Article,,卷期:2011年84-5]
- Retinoic acid (RA) is required for germ cell differentiation, the regulation of which gives rise to a constant production of mature sperm. In testes from 3-day postpartum (dpp) RARE-hsplacZ mice, periodic regions positiv...
- Poly(ADP-Ribose) Polymerases PARP1 and PARP2 Modulate Topoisomerase II Beta (TOP2B) Function During Chromatin Condensation in Mouse Spermiogenesis
[作者:Meyer-Ficca, ML; Lonchar, JD; Ihara, M; Meistrich, ML; Austin, CA; Meyer, RG,期刊:Biology of Reproduction, 页码:900-909 , 文章类型: Article,,卷期:2011年84-5]
- To achieve the specialized nuclear structure in sperm necessary for fertilization, dramatic chromatin reorganization steps in developing spermatids are required where histones are largely replaced first by transition pro...
- Expression, Regulation, and Function of Progesterone Receptors in Bovine Cumulus Oocyte Complexes During In Vitro Maturation
[作者:Aparicio, IM; Garcia-Herreros, M; O'Shea, LC; Hensey, C; Lonergan, P; Fair, T,期刊:Biology of Reproduction, 页码:910-921 , 文章类型: Article,,卷期:2011年84-5]
- Progesterone (P4) exerts its effects by binding to specific genomic (nPR-A/B) and non-genomic (mPRalpha/beta, PGRMC1/2) receptors. P4 has a role in the regulation of the ovulatory cycle, but its participation in oocyte m...
- Pulsatility and Interrelationships of 13,14-Dihydro-15-Keto-PGF2alpha (PGFM), Luteinizing Hormone, Progesterone, and Estradiol in Heifers
[作者:Ginther, OJ; Fuenzalida, MJ; Hannan, MA; Beg, MA,期刊:Biology of Reproduction, 页码:922-932 , 文章类型: Article,,卷期:2011年84-5]
- Temporality among episodes of a prostaglandin F2alpha metabolite (PGFM), progesterone (P4), luteinizing hormone (LH), and estradiol (E2) were studied during preluteolysis and luteolysis. A vehicle group (n = 10) and a gr...
- Loss of Methylation at H19 DMD Is Associated with Biallelic Expression and Reduced Development in Cattle Derived by Somatic Cell Nuclear Transfer
[作者:Suzuki, J; Therrien, J; Filion, F; Lefebvre, R; Goff, AK; Perecin, F; Meirelles, FV; Smith, LC,期刊:Biology of Reproduction, 页码:947-956 , 文章类型: Article,,卷期:2011年84-5]
- Although cloning of mammals has been achieved successfully, the percentage of live offspring is very low because of reduced fetal size and fewer implantation sites. Recent studies have attributed such pathological condit...
- Suppression of Stra8 Expression in the Mouse Gonad by WIN 18,446
[作者:Hogarth, CA; Evanoff, R; Snyder, E; Kent, T; Mitchell, D; Small, C; Amory, JK; Griswold, MD,期刊:Biology of Reproduction, 页码:957-965 , 文章类型: Article,,卷期:2011年84-5]
- Bis-(dichloroacetyl)-diamines (BDADs) are compounds that inhibit spermatogenesis and function as male contraceptives in many species; however, their mechanism of action has yet to be fully investigated. It has been propo...
- ATP Synthesis, Mitochondrial Function, and Steroid Biosynthesis in Rodent Primary and Tumor Leydig Cells
[作者:Midzak, AS; Chen, HL; Aon, MA; Papadopoulos, V; Zirkin, BR,期刊:Biology of Reproduction, 页码:976-985 , 文章类型: Article,,卷期:2011年84-5]
- Previous studies in MA-10 tumor Leydig cells demonstrated that disruption of the mitochondrial electron-transport chain (ETC), membrane potential (Delta Psi(m)), or ATP synthesis independently inhibited steroidogenesis. ...
- Induction of Dual-Specificity Phosphatase 1 (DUSP1) by Pulsatile Gonadotropin-Releasing Hormone Stimulation: Role for Gonadotropin Subunit Expression in Mouse Pituitary LbetaT2 Cells
[作者:Purwana, IN; Kanasaki, H; Mijiddorj, T; Oride, A; Miyazaki, K,期刊:Biology of Reproduction, 页码:996-1004 , 文章类型: Article,,卷期:2011年84-5]
- In pituitary gonadotrophs, GnRH induces expression of the mitogen-activated protein kinases (MAPK3/1) dephosphorylating enzyme, dual-specificity phosphatase 1 (DUSP1). Here we examined DUSP1 expression levels following p...
- Testicular Signaling Is the Potential Target of Perfluorooctanesulfonate-Mediated Subfertility in Male Mice
[作者:Wan, HT; Zhao, YG; Wong, MH; Lee, KF; Yeung, WSB; Giesy, JP; Wong, CKC,期刊:Biology of Reproduction, 页码:1016-1023 , 文章类型: Article,,卷期:2011年84-5]
- Perfluorooctanesulfonate (PFOS) was produced and used by various industries and in consumer products. Because of its persistence, it is ubiquitous in air, water, soil, wildlife, and humans. Although the adverse effects o...
- The Fused Toes Locus Is Essential for Somatic-Germ Cell Interactions That Foster Germ Cell Maturation in Developing Gonads in Mice
[作者:Kim, B; Kim, Y; Cooke, PS; Ruther, U; Jorgensen, JS,期刊:Biology of Reproduction, 页码:1024-1032 , 文章类型: Article,,卷期:2011年84-5]
- Ovarian development absolutely depends on communication between somatic and germ cell components. In contrast, it is not until after birth that interactions between somatic and germ cells play an important role in testic...
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