- Inhibition of prostaglandin synthesis and actions by genistein in human prostate cancer cells and by soy isoflavones in prostate cancer patients
[作者:Swami, S; Krishnan, AV; Moreno, J; Bhattacharya, RS; Gardner, C; Brooks, JD; Peehl, DM; Feldman, D,期刊:International Journal of Cancer, 页码:2050-2059 , 文章类型: Article,,卷期:2009年124-9]
- Soy and its constituent isoflavone genistein inhibit the development and progression of prostate cancer (PCa). Our study in both cultured cells and PCa patients reveals a novel pathway for the actions of genistein, namel...
- Physical activity, sedentary behavior, and endometrial cancer risk in the NIH-AARP Diet and Health Study
[作者:Gierach, GL; Chang, SC; Brinton, LA; Lacey, JV; Hollenbeck, AR; Schatzkin, A; Leitzmann, MF,期刊:International Journal of Cancer, 页码:2139-2147 , 文章类型: Article,,卷期:2009年124-9]
- Consistent with a strong hormonal etiology, endometrial cancer is thought to be influenced by both obesity and physical activity. Although obesity has been consistently related to risk, associations with physical activit...
- Dopamine D-2 receptor polymorphisms and adenoma recurrence in the Polyp Prevention Trial
[作者:Murphy, G; Cross, AJ; Sansbury, LS; Bergen, A; Laiyemo, AO; Albert, PS; Wang, ZQ; Yu, BB; Lehman, T; Kalidindi, A; Modali, R; Schatzkin, A; Lanza, E,期刊:International Journal of Cancer, 页码:2148-2151 , 文章类型: Article,,卷期:2009年124-9]
- Epidemiological evidence suggests that obesity may be causally associated with colorectal cancer. Dopamine and the dopaminergic reward pathway have been implicated in drug and alcohol addiction as well as obesity. Polymo...
- Estimation of the effects of smoking and DNA repair capacity on coefficients of a carcinogenesis model for lung cancer
[作者:Deng, L; Kimmel, M; Foy, M; Spitz, M; Wei, QY; Gorlova, O,期刊:International Journal of Cancer, 页码:2152-2158 , 文章类型: Article,,卷期:2009年124-9]
- Numerous prospective and retrospective studies have clearly demonstrated a dose-related increased lung cancer risk associated with cigarette smoking, with evidence also for a genetic component to risk. In this study, usi...
- Putative functional polymorphisms of MMP9 predict survival of NSCLC in a Chinese population
[作者:Jin, GF; Miao, RF; Hu, ZB; Xu, L; Huang, XE; Chen, YJ; Tian, T; Wei, QY; Boffetta, P; Shen, HB,期刊:International Journal of Cancer, 页码:2172-2178 , 文章类型: Article,,卷期:2009年124-9]
- Matrix metalloproteinases (MMPs) play a crucial role in cancer progression and their over-expression is often associated with unfavorable survival of non-small cell lung cancer (NSCLC). Because genetic variants can alter...
- Polymorphic loci of E2F2, CCND1 and CCND3 are associated with HER2 status of breast tumors
[作者:Justenhoven, C; Pierl, CB; Haas, S; Fischer, HP; Hamann, U; Baisch, C; Harth, V; Spickenheuer, A; Rabstein, S; Vollmert, C; Illig, T; Pesch, B; Bruning, T; Dippon, J; Ko, YD; Brauch, H,期刊:International Journal of Cancer, 页码:2077-2081 , 文章类型: Article,,卷期:2009年124-9]
- Overexpression of the human epidermal growth factor receptor 2 (HER2) in breast tumors is associated with bad prognosis. Therefore, it is highly relevant to further improve understanding of the regulatory mechanisms of H...
- Pharmaeogenomics and analogues of the antitumour agent N-6-isopentenyladenosine
[作者:Colombo, F; Falvella, FS; De Cecco, L; Tortoreto, M; Pratesi, G; Ciuffreda, P; Ottria, R; Santaniello, E; Cicatiello, L; Weisz, A; Dragani, TA,期刊:International Journal of Cancer, 页码:2179-2185 , 文章类型: Article,,卷期:2009年124-9]
- N-6-isopentenyladenosine (i(6)A), a member of the cytokinin family of plant hormones, has potent in vitro antitumour activity in different types or human epithelial cancer cell lines. Gene expression profile. analysis of...
- Trichomonosis and subsequent risk of prostate cancer in the Prostate Cancer Prevention Trial
[作者:Sutcliffe, S; Alderete, JF; Till, C; Goodman, PJ; Hsing, AW; Zenilman, JM; De Marzo, AM; Platz, EA,期刊:International Journal of Cancer, 页码:2082-2087 , 文章类型: Article,,卷期:2009年124-9]
- We previously observed a positive association between a history of trichomonosis, a sexually transmitted infection caused by the protozoan, Trichomonas vaginalis, and prostate cancer risk in the Health Professionals Foll...
- The effect of cantharidins on leukemic stem cells
[作者:Dorn, DC; Kou, CA; Png, KJ; Moore, MAS,期刊:International Journal of Cancer, 页码:2186-2199 , 文章类型: Article,,卷期:2009年124-9]
- To identify an agent with specific activity against leukemic stem cells (LSCs), we evaluated compounds that targeted hepatic leukemia factor (HLF), a gene implicated in hematopoietic stem cell (HSCs) regulation, that we ...
- The methylenetetrahydrofolate reductase C677T mutation induces cell-specific changes in genomic DNA methylation and uracil misincorporation: A possible molecular basis for the site-specific cancer risk modification
[作者:Sohn, KJ; Jang, H; Campan, M; Weisenberger, DJ; Dickhout, J; Wang, YC; Cho, RC; Yates, Z; Lucock, M; Chiang, EP; Austin, RC; Choi, SW; Laird, PW; Kim, YI,期刊:International Journal of Cancer, 页码:1999-2005 , 文章类型: Article,,卷期:2009年124-9]
- The C677T polymorphism in the methylenetetrahydrofolate reductase (MTHFR) gene is associated with a decreased risk of colon cancer although it may, increase the risk of breast cancer. This polymorphism is associated with...
- Increased claudin-4 expression is associated with poor prognosis and high tumour grade in breast cancer
[作者:Lanigan, F; McKiernan, E; Brennan, DJ; Hegarty, S; Millikan, RC; McBryan, J; Jirstrom, K; Landberg, G; Martin, F; Duffy, MJ; Gallagher, WM,期刊:International Journal of Cancer, 页码:2088-2097 , 文章类型: Article,,卷期:2009年124-9]
- The role of intercellular tight junctions in breast epithelia[ cells is traditionaliy thought to be in maintaining polarity and barrier function. However, claudin-4, a tight junction protein, is overexpressed in breast t...
- Salvianolic acid B inhibits growth of head and neck squamous cell carcinoma in vitro and in vivo via cyclooxygenase-2 and apoptotic pathways
[作者:Hao, YB; Xie, TP; Korotcov, A; Zhou, YF; Pang, XW; Shan, L; Ji, HG; Sridhar, R; Wang, P; Califano, J; Giu, XB,期刊:International Journal of Cancer, 页码:2200-2209 , 文章类型: Article,,卷期:2009年124-9]
- Overexpression of cyclooxygenase-2 (COX-2) in oral mucosa has been associated with increased risk of head and neck squamous cell carcinoma (HNSCC). Celecoxib is a nonsteroidal anti-inflammatory drug, which inhibits COX-2...
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