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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共17条记录   Inducible deletion of epidermal Dicer and Drosha reveals multiple functions for miRNAs in postnatal skin [作者：Teta, M; Choi, YS; Okegbe, T; Wong, G; Tam, OH; Chong, MMW; Seykora, JT; Nagy, A; Littman, DR; Andl, T; Millar, SE,期刊：Development, 页码：1405-1416 , 文章类型： Article，,卷期：2012年139-8] MicroRNAs (miRNAs) regulate the expression of many mammalian genes and play key roles in embryonic hair follicle development; however, little is known of their functions in postnatal hair growth. We compared the effects ... Cell movements of the deep layer of non-neural ectoderm underlie complete neural tube closure in Xenopus [作者：Morita, H; Kajiura-Kobayashi, H; Takagi, C; Yamamoto, TS; Nonaka, S; Ueno, N,期刊：Development, 页码：1417-1426 , 文章类型： Article，,卷期：2012年139-8] In developing vertebrates, the neural tube forms from a sheet of neural ectoderm by complex cell movements and morphogenesis. Convergent extension movements and the apical constriction along with apical-basal elongation ... Drosophila miR-124 regulates neuroblast proliferation through its target anachronism [作者：Weng, RF; Cohen, SM,期刊：Development, 页码：1427-1434 , 文章类型： Article，,卷期：2012年139-8] MicroRNAs (miRNAs) have been implicated as regulators of central nervous system (CNS) development and function. miR-124 is an evolutionarily ancient, CNS-specific miRNA. On the basis of the evolutionary conservation of i... Motor axon exit from the mammalian spinal cord is controlled by the homeodomain protein Nkx2.9 via Robo-Slit signaling [作者：Bravo-Ambrosio, A; Mastick, G; Kaprielian, Z,期刊：Development, 页码：1435-1446 , 文章类型： Article，,卷期：2012年139-8] Mammalian motor circuits control voluntary movements by transmitting signals from the central nervous system (CNS) to muscle targets. To form these circuits, motor neurons (MNs) must extend their axons out of the CNS. Al... The transcriptional co-repressor Grg3/Tle3 promotes pancreatic endocrine progenitor delamination and beta-cell differentiation [作者：Metzger, DE; Gasperowicz, M; Otto, F; Cross, JC; Gradwohl, G; Zaret, KS,期刊：Development, 页码：1447-1456 , 文章类型： Article，,卷期：2012年139-8] Pancreatic beta-cells arise from Ngn3(+) endocrine progenitors within the trunk epithelium of the embryonic pancreas. The emergence of endocrine cells requires E-cadherin downregulation, but the crucial steps that elicit... Differential regulation of mesodermal gene expression by Drosophila cell type-specific Forkhead transcription factors [作者：Zhu, XM; Ahmad, SM; Aboukhalil, A; Busser, BW; Kim, Y; Tansey, TR; Haimovich, A; Jeffries, N; Bulyk, ML; Michelson, AM,期刊：Development, 页码：1457-1466 , 文章类型： Article，,卷期：2012年139-8] A common theme in developmental biology is the repeated use of the same gene in diverse spatial and temporal domains, a process that generally involves transcriptional regulation mediated by multiple separate enhancers, ... Neurula rotation determines left-right asymmetry in ascidian tadpole larvae [作者：Nishide, K; Mugitani, M; Kumano, G; Nishida, H,期刊：Development, 页码：1467-1475 , 文章类型： Article，,卷期：2012年139-8] Tadpole larvae of the ascidian Halocynthia roretzi show morphological left-right asymmetry. The tail invariably bends towards the left side within the vitelline membrane. The structure of the larval brain is remarkably a... Xenopus Nanos1 is required to prevent endoderm gene expression and apoptosis in primordial germ cells [作者：Lai, FF; Singh, A; King, ML,期刊：Development, 页码：1476-1486 , 文章类型： Article，,卷期：2012年139-8] Nanos is expressed in multipotent cells, stem cells and primordial germ cells (PGCs) of organisms as diverse as jellyfish and humans. It functions together with Pumilio to translationally repress targeted mRNAs. Here we ... A hindbrain-repressive Wnt3a/Meis3/Tsh1 circuit promotes neuronal differentiation and coordinates tissue maturation [作者：Elkouby, YM; Polevoy, H; Gutkovich, YE; Michaelov, A; Frank, D,期刊：Development, 页码：1487-1497 , 文章类型： Article，,卷期：2012年139-8] During development, early inducing programs must later be counterbalanced for coordinated tissue maturation. In Xenopus laevis embryos, activation of the Meis3 transcription factor by a mesodermal Wnt3a signal lies at th... Separating planar cell polarity and Hippo pathway activities of the protocadherins Fat and Dachsous [作者：Matakatsu, H; Blair, SS,期刊：Development, 页码：1498-1508 , 文章类型： Article，,卷期：2012年139-8] The giant Drosophila protocadherin Fat (Ft) affects planar cell polarity (PCP). Ft also inhibits the overgrowth of imaginal discs via the Hippo pathway, repressing the activity of the transcription co-factor Yorkie (Yki)... Context-dependent function of a conserved translational regulatory module [作者：Liu, QW; Stumpf, C; Thomas, C; Wickens, M; Haag, ES,期刊：Development, 页码：1509-1521 , 文章类型： Article，,卷期：2012年139-8] The modification of transcriptional regulation is a well-documented evolutionary mechanism in both plants and animals, but post-transcriptional controls have received less attention. The derived hermaphrodite of C. elega... Dermal beta-catenin activity in response to epidermal Wnt ligands is required for fibroblast proliferation and hair follicle initiation [作者：Chen, DM; Jarrell, A; Guo, CT; Lang, R; Atit, R,期刊：Development, 页码：1522-1533 , 文章类型： Article，,卷期：2012年139-8] Dermal fibroblasts are required for structural integrity of the skin and for hair follicle development. Uniform Wnt signaling activity is present in dermal fibroblast precursors preceding hair follicle initiation, but th... An interview with Jose Xavier Neto [作者：Amsen, E; Neto, JX,期刊：Development, 页码：1369-1370 , 文章类型： Editorial Material，,卷期：2012年139-8] Diverse roles for VEGF-A in the nervous system [作者：Mackenzie, F; Ruhrberg, C,期刊：Development, 页码：1371-1380 , 文章类型： Review，,卷期：2012年139-8] Vascular endothelial growth factor A (VEGF-A) is best known for its essential roles in blood vessel growth. However, evidence has emerged that VEGF-A also promotes a wide range of neuronal functions, both in vitro and in... The receptor tyrosine phosphatase Lar regulates adhesion between Drosophila male germline stem cells and the niche [作者：Srinivasan, S; Mahowald, AP; Fuller, MT,期刊：Development, 页码：1381-1390 , 文章类型： Article，,卷期：2012年139-8] The stem cell niche provides a supportive microenvironment to maintain adult stem cells in their undifferentiated state. Adhesion between adult stem cells and niche cells or the local basement membrane ensures retention ... Control of embryonic meristem initiation in Arabidopsis by PHD-finger protein complexes [作者：Saiga, S; Moller, B; Watanabe-Taneda, A; Abe, M; Weijers, D; Komeda, Y,期刊：Development, 页码：1391-1398 , 文章类型： Article，,卷期：2012年139-8] Plant growth is directed by the activity of stem cells within meristems. The first meristems are established during early embryogenesis, and this process involves the specification of both stem cells and their organizer ...