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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共20条记录   The C-terminus of MIP-T3 protein is required for ubiquitin-proteasome-mediated degradation in human cells [作者：Guo, CW; Liu, G; Xiong, S; Ge, F; Fuse, T; Wang, YF; Kitazato, K,期刊：FEBS Letters, 页码：1350-1356 , 文章类型： Article，,卷期：2011年585-9] The intraflagellar transport (IFT) complex is essential for the formation and functional maintenance of eukaryotic cilia which play a vital role in development and tissue homeostasis. However, the biochemical characteris... Association of cholera toxin with Vibrio cholerae outer membrane vesicles which are internalized by human intestinal epithelial cells [作者：Chatterjee, D; Chaudhuri, K,期刊：FEBS Letters, 页码：1357-1362 , 文章类型： Article，,卷期：2011年585-9] Cholera toxin (CT) is the major virulence factor of pathogenic Vibrio cholerae. The present study demonstrates that a fraction of CT is associated with the outer membrane vesicles (OMVs) released by V. cholerae. Atomic f... MicroRNA-26b is underexpressed in human breast cancer and induces cell apoptosis by targeting SLC7A11 [作者：Liu, XX; Li, XJ; Zhang, B; Liang, YJ; Zhou, CX; Cao, DX; He, M; Chen, GQ; He, JR; Zhao, Q,期刊：FEBS Letters, 页码：1363-1367 , 文章类型： Article，,卷期：2011年585-9] MicroRNAs are widely dysregulated in various cancers and integrated into tumorigenic programs as either oncogenes or tumor suppressor genes. Here, we show that miR-26b, which is down-regulated in human breast cancer spec... Orexin/hypocretin receptor chimaeras reveal structural features important for orexin peptide distinction [作者：Putula, J; Turunen, PM; Johansson, L; Nasman, J; Ra, R; Korhonen, L; Kukkonen, JP,期刊：FEBS Letters, 页码：1368-1374 , 文章类型： Article，,卷期：2011年585-9] We wanted to analyze the basis for the distinction between OX1 and OX2 orexin receptors by the known agonists, orexin-A, orexin-B and Ala(11), D-Leu(15)-orexin-B, of which the latter two show some selectivity for OX2. Fo... Novel role of RGS2 in regulation of antioxidant homeostasis in neuronal cells [作者：Salim, S; Asghar, M; Taneja, M; Hovatta, I; Wu, YL; Saha, K; Sarraj, N; Hite, B,期刊：FEBS Letters, 页码：1375-1381 , 文章类型： Article，,卷期：2011年585-9] Regulator of G-protein signaling protein (RGS)-2 is a modulator of anxiety and dysregulation of oxidative stress is implicated in anxiety. Also, RGS2 expression is reported to be induced by oxidative stress. Thus, if oxi... Mitochondrial consumption of cytosolic ATP: Not so fast [作者：Chinopoulos, C,期刊：FEBS Letters, 页码：1255-1259 , 文章类型： Review，,卷期：2011年585-9] In various pathologic circumstances depolarized mitochondria are thought to precipitate cell death by avidly consuming cytosolic ATP. However, for as long as the inner mitochondrial membrane remains intact the reversal p... Chelerythrine perturbs lamellar actomyosin filaments by selective inhibition of myotonic dystrophy kinase-related Cdc42-binding kinase [作者：Tan, I; Lai, J; Yong, J; Li, SFY; Leung, T,期刊：FEBS Letters, 页码：1260-1268 , 文章类型： Article，,卷期：2011年585-9] Cell movement requires forces generated by non-muscle myosin II (NM II) for coordinated protrusion and retraction. The Cdc42/Rac effector MRCK regulates a specific actomyosin network in the lamella essential for cell pro... Nuclear receptor SHP inhibition of Dnmt1 expression via ERR gamma [作者：Zhang, YX; Wang, L,期刊：FEBS Letters, 页码：1269-1275 , 文章类型： Article，,卷期：2011年585-9] We describe a transcriptional mechanism regulating the expression of Dnmt1 by nuclear receptors. We show that ERR gamma functions as a transcriptional activator of mouse and human Dnmt1 expression by direct binding to it... Co-translational function of Cosmc, core 1 synthase specific molecular chaperone, revealed by a cell-free translation system [作者：Narimatsu, Y; Kubota, T; Furukawa, S; Shimojima, M; Iwasaki, H; Tozawa, Y; Tachibana, K; Narimatsu, H,期刊：FEBS Letters, 页码：1276-1280 , 文章类型： Article，,卷期：2011年585-9] The core 1 structure of the mucin type O-glycan is synthesized by core 1 beta 1,3-galactosyltransferase (C1GalT). Core 1 synthase specific molecular chaperone (Cosmc), a molecular chaperone specific for C1GalT, is essent... Recognition of an ERAD-L substrate analyzed by site-specific in vivo photocrosslinking [作者：Stanley, AM; Carvalho, P; Rapoport, T,期刊：FEBS Letters, 页码：1281-1286 , 文章类型： Article，,卷期：2011年585-9] Misfolded, luminal endoplasmic reticulum (ER) proteins must be recognized before being degraded by a process called ERAD-L. Using site-specific photocrosslinking in Saccharomyces cerevisiae, we tested luminal interaction... Stabilization of the survival motor neuron protein by ASK1 [作者：Kwon, JE; Kim, EK; Choi, EJ,期刊：FEBS Letters, 页码：1287-1292 , 文章类型： Article，,卷期：2011年585-9] The survival motor neuron (SMN) is a spliceosomal snRNP-interacting protein that was initially identified as a defective molecule in spinal muscular atrophy (SMA). The disease severity of SMA is determined by SMN protein... Diversity in DNA recognition by heat shock transcription factors (HSFs) from model organisms [作者：Enoki, Y; Sakurai, H,期刊：FEBS Letters, 页码：1293-1298 , 文章类型： Article，,卷期：2011年585-9] Heat shock transcription factor (HSF), an evolutionarily conserved heat-responsive regulator, binds to heat shock elements (HSEs) comprising continuous inverted repeats of the pentamer nGAAn. Here, we analyzed DNA-bindin... Cyanidioschyzon merolae ferredoxin: A high resolution crystal structure analysis and its thermal stability [作者：Yamaoka, A; Ozawa, Y; Ueno, Y; Endo, T; Morimoto, Y; Urushiyama, A; Ohmori, D; Imai, T,期刊：FEBS Letters, 页码：1299-1302 , 文章类型： Article，,卷期：2011年585-9] Cyanidioschyzon merolae (Cm) is a single-cell red alga that grows under moderately thermophilic (40-50 degrees C), acidic (pH 1-3) conditions. We purified a Cm ferredoxin (Fd) that was characterized as a plant-type [2Fe-... Conditional expression of constitutively active estrogen receptor alpha in osteoblasts increases bone mineral density in mice [作者：Ikeda, K; Tsukui, T; Horie-Inoue, K; Inoue, S,期刊：FEBS Letters, 页码：1303-1309 , 文章类型： Article，,卷期：2011年585-9] Estrogen plays an important role in maintaining bone density in women. Estrogen receptor (ER) is expressed in osteoblasts and osteoclasts; however, the precise mechanism of ER in bone is not fully understood. In the pres... DHS-21, a dicarbonyl/L-xylulose reductase (DCXR) ortholog, regulates longevity and reproduction in Caenorhabditis elegans [作者：Son, LT; Ko, KM; Cho, JH; Singaravelu, G; Chatterjee, I; Choi, TW; Song, HO; Yu, JR; Park, BJ; Lee, SK; Ahnn, J,期刊：FEBS Letters, 页码：1310-1316 , 文章类型： Article，,卷期：2011年585-9] Dicarbonyl/L-xylulose reductase (DCXR) converts L-xylulose into xylitol, and reduces various a-dicarbonyl compounds, thus performing a dual role in carbohydrate metabolism and detoxification. In this study, we identified... Conversion of a decarboxylating to a non-decarboxylating glutaryl-coenzyme A dehydrogenase by site-directed mutagenesis [作者：Schaarschmidt, J; Wischgoll, S; Hofmann, HJ; Boll, M,期刊：FEBS Letters, 页码：1317-1321 , 文章类型： Article，,卷期：2011年585-9] Glutaryl-coenzyme A (CoA) dehydrogenases (GDHs) are acyl-CoA dehydrogenases, which usually dehydrogenate and decarboxylate the substrate to crotonyl-CoA. In some anaerobic bacteria, non-decarboxylating GDHs exist that re...