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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共47条记录   Aurora kinase A critically contributes to the resistance to anti-cancer drug cisplatin in JAK2 V617F mutant-induced transformed cells [作者：Sumi, K; Tago, K; Kasahara, T; Funakoshi-Tago, M,期刊：FEBS Letters, 页码：1884-1890 , 文章类型： Article，,卷期：2011年585-12] JAK2 V617F mutant induces transformation through aberrant activation of various transcription factors. We found that the expression of Aurora kinase A (Aurka) was significantly induced by mutant JAK2 through c-Myc expres... The mitochondrial cytochrome c N-terminal region is critical for maturation by holocytochrome c synthase [作者：Stevens, JM; Zhang, YL; Muthuvel, G; Sam, KA; Allen, JWA; Ferguson, SJ,期刊：FEBS Letters, 页码：1891-1896 , 文章类型： Article，,卷期：2011年585-12] The covalent attachment of heme to mitochondrial cytochrome c is catalysed by holocytochrome c synthase (HCCS, also called heme lyase). How HCCS functions and recognises the substrate apocytochrome is unknown. Here we ha... MicroRNA regulation constrains the organization of target genes on mammalian chromosomes [作者：Wang, ZZ; Gong, BS; Wang, HK; Wang, HJ; Zhou, M; Wang, QH; Chen, X; Liu, T; Li, X,期刊：FEBS Letters, 页码：1897-1904 , 文章类型： Article，,卷期：2011年585-12] The regulation of microRNAs (miRNAs) is a complicated process requiring a large number of molecular events to be coordinated in both space and time. It is not known whether this complicated regulation process constrains ... Thioredoxin 2 from Escherichia coli is not involved in vivo in the recycling process of methionine sulfoxide reductase activities [作者：Jacob, C; Kriznik, A; Boschi-Muller, S; Branlant, G,期刊：FEBS Letters, 页码：1905-1909 , 文章类型： Article，,卷期：2011年585-12] Thioredoxins (Trx) 1 and 2, and three methionine sulfoxide reductases (Msr) whose activities are Trx-dependent, are expressed in Escherichia coli. A metB(1) trxA mutant was shown to be unable to grow on methionine sulfox... The ASPP proteins complex and cooperate with p300 to modulate the transcriptional activity of p53 [作者：Gillotin, S; Lu, X,期刊：FEBS Letters, 页码：1778-1782 , 文章类型： Article，,卷期：2011年585-12] Understanding how p53 is able to specifically respond to particular stress signals and regulate many different signalling pathways remains a challenge. Several studies have demonstrated that p53's interactions with diffe... Zinc binding to human lactogenic hormones and the human prolactin receptor [作者：Voorhees, JL; Rao, GV; Gordon, TJ; Brooks, CL,期刊：FEBS Letters, 页码：1783-1788 , 文章类型： Article，,卷期：2011年585-12] Zinc half sites are present in all human lactogenic hormones: human prolactin (hPRL), growth hormone (hGH), placental lactogens (hPL) and the hPRL receptor (hPRLr). The influence of divalent zinc (Zn2+) as measured by in... Knockdown of thioredoxin interacting protein attenuates high glucose-induced apoptosis and activation of ASK1 in mouse mesangial cells [作者：Shi, YH; Ren, YZ; Zhao, LJ; Du, CY; Wang, YH; Zhang, YL; Li, Y; Zhao, S; Duan, HJ,期刊：FEBS Letters, 页码：1789-1795 , 文章类型： Article，,卷期：2011年585-12] Mesangial cell apoptosis contributes to the pathogenesis of diabetic nephropathy. Here we show that thioredoxin interacting protein (TXNIP) is involved in high glucose (HG)-induced mouse mesangial cell (MMC) apoptosis. H... Influence of Ca2+ and pH on the folding of the prourotensin II precursor [作者：Bilodeau, J; Desilets, A; McDuff, FO; St-Pierre, C; Barbar, E; Leduc, R; Lavigne, P,期刊：FEBS Letters, 页码：1910-1914 , 文章类型： Article，,卷期：2011年585-12] Proper folding is a crucial step for the trafficking of proteins through the secretory pathway. We hypothesized that the secretory granules of endocrine cells provide optimal folding conditions of prohormone precursors f... c-Jun/AP-1 transcription factor regulates laminin-1-induced neurite outgrowth in human bone marrow mesenchymal stem cells: Role of multiple signaling pathways [作者：Mruthyunjaya, S; Rumma, M; Ravibhushan, G; Anjali, S; Padma, S,期刊：FEBS Letters, 页码：1915-1922 , 文章类型： Article，,卷期：2011年585-12] In this study, we demonstrated that laminin-1 (LM-1) induces neurite outgrowth and enhances the expression of neurofilament-L and MAP2 in human bone marrow mesenchymal stem cells (MSCs). The c-Jun transcription factor wa... Anaphase DNA bridges induced by lack of RecQ5 in Drosophila syncytial embryos [作者：Sakurai, H; Okado, M; Ito, F; Kawasaki, K,期刊：FEBS Letters, 页码：1923-1928 , 文章类型： Article，,卷期：2011年585-12] Drosophila melanogaster RecQ5, a member of the RecQ family, is expressed in early embryos. The loss of maternally-derived RecQ5 leads to spontaneous mitotic defects in syncytial embryos. We demonstrate that the mitotic d... Reduced expression of the DOG1 gene in Arabidopsis mutant seeds lacking the transcript elongation factor TFIIS [作者：Mortensen, SA; Sonderkaer, M; Lynggaard, C; Grasser, M; Nielsen, KL; Grasser, KD,期刊：FEBS Letters, 页码：1929-1933 , 文章类型： Article，,卷期：2011年585-12] TFIIS is a transcript elongation factor that facilitates transcription by RNA polymerase II through blocks to elongation. Arabidopsis plants lacking TFIIS are affected in seed dormancy, which represents a block to comple... How do you RUN on? [作者：Yoshida, H; Kitagishi, Y; Okumura, N; Murakami, M; Nishimura, Y; Matsuda, S,期刊：FEBS Letters, 页码：1707-1710 , 文章类型： Review，,卷期：2011年585-12] RUN domain is present in several proteins related to the functions of Rap and Rab family GTPases. Accumulating evidence supports the hypothesis that RUN domain-containing proteins act as a component of vesicle traffic an... Unravelling the different functions of protein kinase C isoforms in platelets [作者：Heemskerk, JWM; Harper, MT; Cosemans, JMEM; Poole, AW,期刊：FEBS Letters, 页码：1711-1716 , 文章类型： Article，,卷期：2011年585-12] Platelets tightly regulate haemostasis and arterial thrombosis. Protein kinase C (PKC) is involved in most platelet responses implicated in thrombus formation. Recent pharmacological and mouse gene knockout approaches sh... A mechanism for regulation of chloroplast LHC II kinase by plastoquinol and thioredoxin [作者：Puthiyaveetil, S,期刊：FEBS Letters, 页码：1717-1721 , 文章类型： Article，,卷期：2011年585-12] State transitions are acclimatory responses to changes in light quality in photosynthesis. They involve the redistribution of absorbed excitation energy between photosystems I and II. In plants and green algae, this redi... Receptor mediated endocytosis 8 is a novel PI(3)P binding protein regulated by myotubularin-related 2 [作者：Xhabija, B; Taylor, GS; Fujibayashi, A; Sekiguchi, K; Vacratsis, PO,期刊：FEBS Letters, 页码：1722-1728 , 文章类型： Article，,卷期：2011年585-12] Myotubularin related protein 2 (MTMR2) is a member of the myotubularin family of phosphoinositide lipid phosphatases. Although MTMR2 dephosphorylates the phosphoinositides PI(3)P and PI(3,5)P2, the phosphoinositide bindi... Role of a conserved arginine residue during catalysis in serine palmitoyltransferase [作者：Lowther, J; Charmier, G; Raman, MC; Ikushiro, H; Hayashi, H; Campopiano, DJ,期刊：FEBS Letters, 页码：1729-1734 , 文章类型： Article，,卷期：2011年585-12] All sphingolipid-producing organisms require the pyridoxal 50-phosphate (PLP)-dependent serine palmitoyltransferase (SPT) to catalyse the first reaction on the de novo sphingolipid biosynthetic pathway. SPT is a member o...