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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共8条记录   Replication-competent retrovirus vector-mediated prodrug activator gene therapy in experimental models of human malignant mesothelioma [作者：Kawasaki, Y; Tamamoto, A; Takagi-Kimura, M; Maeyama, Y; Yamaoka, N; Terada, N; Okamura, H; Kasahara, N; Kubo, S,期刊：Cancer gene therapy, 页码：571-578 , 文章类型： Article，,卷期：2011年18-8] Replication-competent retrovirus (RCR) vectors have been shown to achieve significantly enhanced tumor transduction efficiency and therapeutic efficacy in various cancer models. In the present study, we investigated RCR ... Competitive electroporation formulation for cell therapy [作者：Flanagan, M; Gimble, JM; Yu, G; Wu, X; Xia, X; Hu, J; Yao, S; Li, S,期刊：Cancer gene therapy, 页码：579-586 , 文章类型： Article，,卷期：2011年18-8] Established cell transfection via nucleofection relies on nucleofection buffers with unknown and proprietary makeup due to trade secrecy, inhibiting the possibility of using this otherwise effective method for developing... Enhanced specificity of HPV16 E6E7 siRNA by RNA-DNA chimera modification [作者：Yamato, K; Egawa, N; Endo, S; Ui-Tei, K; Yamada, T; Saigo, K; Hyodo, I; Kiyono, T; Nakagawa, I,期刊：Cancer gene therapy, 页码：587-597 , 文章类型： Article，,卷期：2011年18-8] Although efforts have been made to develop new drugs for infectious and neoplastic diseases utilizing synthetic small interfering RNA(siRNAs), those intrinsically have undesirable effects, including silencing of unintend... Comparative analysis of enzyme and pathway engineering strategies for 5FC-mediated suicide gene therapy applications [作者：Johnson, AJ; Ardiani, A; Sanchez-Bonilla, M; Black, ME,期刊：Cancer gene therapy, 页码：533-542 , 文章类型： Article，,卷期：2011年18-8] Bacterial- and yeast-encoded cytosine deaminases (bCD and yCD, respectively) are widely investigated suicide enzymes used in combination with the prodrug 5-fluorocytosine (5FC) to achieve localized cytotoxicity. Yet char... Role of temperature-independent lipoplex-cell membrane interactions in the efficiency boost of multicomponent lipoplexes [作者：Marchini, C; Pozzi, D; Montani, M; Alfonsi, C; Amici, A; De Sanctis, SC; Digman, MA; Sanchez, S; Gratton, E; Amenitsch, H; Fabbretti, A; Gualerzi, CO; Caracciolo, G,期刊：Cancer gene therapy, 页码：543-552 , 文章类型： Article，,卷期：2011年18-8] Multicomponent lipoplexes have recently emerged as especially promising transfection candidates, as they are from 10 to 100 times more efficient than binary complexes usually employed for gene delivery purposes. Previous... Cell encapsulation technology as a novel strategy for human anti-tumor immunotherapy [作者：Schwenter, F; Zarei, S; Luy, P; Padrun, V; Bouche, N; Lee, JS; Mulligan, RC; Morel, P; Mach, N,期刊：Cancer gene therapy, 页码：553-562 , 文章类型： Article，,卷期：2011年18-8] Granulocyte-macrophage colony-stimulating factor (GM-CSF) as an adjuvant in autologous cell-based anti-tumor immunotherapy has recently been approved for clinical application. To avoid the need for individualized process... Induction of the glucocorticoid-induced leucine zipper gene limits the efficacy of dendritic cell vaccines [作者：Lebson, L; Wang, T; Jiang, Q; Whartenby, KA,期刊：Cancer gene therapy, 页码：563-570 , 文章类型： Article，,卷期：2011年18-8] Dendritic cell (DC) vaccines have shown great promise in generating antitumor immune responses but have generally fallen short of producing durable cures. Determining mechanisms by which these vaccines fail will provide ... Armed and targeted measles virus for chemovirotherapy of pancreatic cancer [作者：Bossow, S; Grossardt, C; Temme, A; Leber, MF; Sawall, S; Rieber, EP; Cattaneo, R; von Kalle, C; Ungerechts, G,期刊：Cancer gene therapy, 页码：598-608 , 文章类型： Article，,卷期：2011年18-8] No curative therapy is currently available for locally advanced or metastatic pancreatic cancer. Therefore, new therapeutic approaches must be considered. Measles virus (MV) vaccine strains have shown promising oncolytic...