个性化文献订阅>文章检索

文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共9条记录   Direct cytotoxicity produced by adenoviral-mediated interferon alpha gene transfer in interferon-resistant cancer cells involves ER stress and caspase 4 activation [作者：Yang, Z; Zhang, XQ; Dinney, CNP; Benedict, WF,期刊：Cancer gene therapy, 页码：609-616 , 文章类型： Article，,卷期：2011年18-9] Over the past several years we have obtained considerable evidence indicating that adenoviruses-expressing interferon alpha (Ad-IFN alpha) can overcome resistance to the IFN alpha protein itself. Since cancer cells infec... Radiation enhances long-term metastasis potential of residual hepatocellular carcinoma in nude mice through TMPRSS4-induced epithelial-mesenchymal transition [作者：Li, T; Zeng, ZC; Wang, L; Qiu, SJ; Zhou, JW; Zhi, XT; Yu, HH; Tang, ZY,期刊：Cancer gene therapy, 页码：617-626 , 文章类型： Article，,卷期：2011年18-9] Recurrence and metastasis are frequently observed after radiotherapy for hepatocellular carcinoma (HCC), although upregulation of matrix metalloproteinases (MMPs) and vascular endothelial growth factor (VEGF) induced by ... Enhanced tumor suppression by an ING4/IL-24 bicistronic adenovirus-mediated gene cotransfer in human non-small cell lung cancer cells [作者：Zhu, Y; Lv, H; Xie, Y; Sheng, W; Xiang, J; Yang, J,期刊：Cancer gene therapy, 页码：627-636 , 文章类型： Article，,卷期：2011年18-9] ING4 as a member of inhibitor of growth (ING) tumor suppressor family has potent inhibitory effects on a variety of tumors. Interleukin-24 (IL-24), a cytokine-tumor suppressor, also shows broad-spectrum and tumor-specifi... Baculovirus vectors for antiangiogenesis-based cancer gene therapy [作者：Luo, WY; Shih, YS; Lo, WH; Chen, HR; Wang, SC; Wang, CH; Chien, CH; Chiang, CS; Chuang, YJ; Hu, YC,期刊：Cancer gene therapy, 页码：637-645 , 文章类型： Article，,卷期：2011年18-9] Baculovirus is an insect virus that is non-pathogenic to humans and has emerged as a promising gene therapy vector. Since solid tumor growth/metastasis critically relies on angiogenesis and hEA, a fusion protein comprisi... Inhibitory effects of interferon-gamma plasmid DNA on DMBA-TPA induced mouse skin carcinogenesis [作者：Ko, JH; Jung, BG; Park, YS; Lee, BJ,期刊：Cancer gene therapy, 页码：646-654 , 文章类型： Article，,卷期：2011年18-9] Interferon-gamma (IFN-gamma) exhibits biological activities that are considered to have important roles in tumor suppression. Therefore, the IFN-gamma gene is a potential candidate for in vivo cytokine gene therapy again... Screening siRNAs targeting a novel gene (HA117) and the development of a derivative recombinant adenovirus delivery system [作者：Zheng, GH; Luo, Q; Jin, XQ; Guo, YX; Xu, YH,期刊：Cancer gene therapy, 页码：655-662 , 文章类型： Article，,卷期：2011年18-9] A novel gene, HA117, was discovered in our previous work. Using the pSOS-HUS vector method which we designed at previous study, we screened for small interfering RNAs (siRNAs) that targeted HA117. The pSOS-HUS siRNA scre... Therapeutic effectiveness of intratumorally delivered dendritic cells engineered to express the pro-inflammatory cytokine, interleukin (IL)-32 [作者：Qu, Y; Taylor, JL; Bose, A; Storkus, WJ,期刊：Cancer gene therapy, 页码：663-673 , 文章类型： Article，,卷期：2011年18-9] Interleukin-32 (IL-32) is a pro-inflammatory cytokine conditionally produced by T cells, natural killer (NK) cells, monocytes, epithelial cells and keratinocytes, which has an important role in host resistance against in... Gap junctions in human glioblastomas: implications for suicide gene therapy [作者：Cottin, S; Gould, PV; Cantin, L; Caruso, M,期刊：Cancer gene therapy, 页码：674-681 , 文章类型： Article，,卷期：2011年18-9] Glioblastoma is a very aggressive astrocytic tumor and most patients have 1-year survival time after diagnosis. A promising therapeutic strategy is the local delivery of the herpes simplex virus thymidine kinase gene in ... Application of mRNA regulatory regions to improve tumor specificity of transgene expression [作者：Shepelev, MV; Korobko, EV; Georgiev, GP; Sverdlov, ED; Korobko, IV,期刊：Cancer gene therapy, 页码：682-684 , 文章类型： Article，,卷期：2011年18-9] Efficiency and specificity are two key attributes of anti-cancer drugs including genetic therapeutic agents. We suggest a way to improve specificity of gene therapy drugs based on the ability of 3'-untranslated regions (...