- Systems Biology: The elements and principles of Life
[作者:Westerhoff, HV; Winder, C; Messiha, H; Simeonidis, E; Adamczyk, M; Verma, M; Bruggeman, FJ; Dunn, W,期刊:FEBS Letters, 页码:3882-3890 , 文章类型: Proceedings Paper,,卷期:2009年583-24]
- Systems Biology has a mission that puts it at odds with traditional paradigms of physics and molecular biology, such as the simplicity requested by Occam's razor and minimum energy/maximal efficiency. By referring to bio...
- A unifying view of 21st century systems biology
[作者:Vidal, M,期刊:FEBS Letters, 页码:3891-3894 , 文章类型: Proceedings Paper,,卷期:2009年583-24]
- The idea that multi-scale dynamic complex systems formed by interacting macromolecules and metabolites, cells, organs and organisms underlie some of the most fundamental aspects of life was proposed by a few visionaries ...
- Systems biology from a yeast omics perspective
[作者:Snyder, M; Gallagher, JEG,期刊:FEBS Letters, 页码:3895-3899 , 文章类型: Proceedings Paper,,卷期:2009年583-24]
- Systems biology represents a paradigm shift from the study of individual genes, proteins or other components to that of the analysis of entire pathways, cellular, developmental, or organismal processes. Large scale studi...
- Metabolic systems biology
[作者:Palsson, B,期刊:FEBS Letters, 页码:3900-3904 , 文章类型: Proceedings Paper,,卷期:2009年583-24]
- The first full genome sequences were established in the mid-1990s. Shortly thereafter, genome-scale metabolic network reconstructions appeared. Since that time, we have witnessed an exponential growth in their number and...
- Systems analysis of cellular networks under uncertainty
[作者:Kaltenbach, HM; Dimopoulos, S; Stelling, J,期刊:FEBS Letters, 页码:3923-3930 , 文章类型: Proceedings Paper,,卷期:2009年583-24]
- Besides the often-quoted complexity of cellular networks, the prevalence of uncertainties about components, interactions, and their quantitative features provides a largely underestimated hallmark of current systems biol...
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