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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共36条记录   The Impact of Enzymatic Degradation on the Uptake of Differently Sized Therapeutic Molecules [作者：Erikson, A; Tufto, I; Bjonnum, AB; Bruland, OS; Davies, CD,期刊：Anticancer Research, 页码：3557-3566 , 文章类型： Article，,卷期：2008年28-6A] Background: The extracellular matrix represents a major barrier for drug delivery. This work compares the effects of collagenase and hyaluronidase on tumour uptake and distribution of two differently sized therapeutic mo... Alpha-folate Receptor Expression in Epithelial Ovarian Carcinoma and Non-neoplastic Ovarian Tissue [作者：Markert, S; Lassmann, S; Gabriel, B; Klar, M; Werner, M; Gitsch, G; Kratz, F; Hasenburg, A,期刊：Anticancer Research, 页码：3567-3572 , 文章类型： Article，,卷期：2008年28-6A] Background: The goal of this study was to evaluate the expression pattern and intracellular localization of alpha-folate receptor (alpha-FR) protein in human ovarian carcinoma compared with non-neoplastic ovarian tissue.... Role of Caspases in 5-FU and Selenium-induced Growth Inhibition of Colorectal Cancer Cells [作者：Thant, AA; Wu, YY; Lee, J; Mishra, DK; Garcia, H; Koeffler, HP; Vadgama, JV,期刊：Anticancer Research, 页码：3579-3592 , 文章类型： Article，,卷期：2008年28-6A] Background: The mechanisms that could explain the poor sensitivity to 5-FU in certain colorectal cancer (CRC) cells were investigated and whether or not co-treatment with low doses of selenium would offer a therapeutic b... Pioglitazone, a Ligand for Peroxisome Proliferator-activated Receptor-gamma Acts as an Inhibitor of Colon Cancer Liver Metastasis [作者：Takano, S; Kubota, T; Nishibori, H; Hasegawa, H; Ishii, Y; Nitori, N; Ochiai, H; Okabayashi, K; Kitagawa, Y; Watanabe, M; Kitajima, M,期刊：Anticancer Research, 页码：3593-3599 , 文章类型： Article，,卷期：2008年28-6A] Background: Peroxisome proliferator-activated receptor-gamma (PPAR gamma) is a member of the steroid receptor superfamily. Liganded PPAR gamma can inhibit cancer cell proliferation. The in vitro and in vivo inhibitory ef... Radioprotection of Murine Gastrointestinal Epithelium by Interleukin-1 alpha Involves Down-regulation of the Apoptotic Response [作者：Johnke, RM; Smith, ES; Cariveau, MJ; Evans, MJ; Kilburn, JM; Bakken, NTG; Nangami, GN,期刊：Anticancer Research, 页码：3601-3607 , 文章类型： Article，,卷期：2008年28-6A] Background: Interleukin-1 alpha (IL-1) is known to radioprotect the gastrointestinal tract, but the mechanism by which this protection occurs remains unclear. These studies were undertaken to investigate whether the radi... Genomic Profile of Colon Cancer Metastases [作者：Zeitoun, G; Mourra, N; Blanche-Koch, H; Thomas, G; Olschwang, S,期刊：Anticancer Research, 页码：3609-3612 , 文章类型： Article，,卷期：2008年28-6A] Background: In colon cancer, the occurrence of metastases is associated with microsatellite stability. As metastatic cells derive from a clonal expansion of primary tumor cells, specific genomic alterations are expected ... Dietary Sphingomyelin Inhibits Colonic Tumorigenesis with an Up-regulation of Alkaline Sphingomyelinase Expression in ICR Mice [作者：Zhang, P; Baixiang, X; Gao, SY; Duan, RD,期刊：Anticancer Research, 页码：3631-3635 , 文章类型： Article，,卷期：2008年28-6A] Background: Sphingomyelin (SM) hydrolysis generates biologically active products regulating cell growth, differentiation and apoptosis. Dietary SM has been found to inhibit colonic tumorigenesis. Alkaline sphingomyelinas... Combined Oncolytic Virotherapy with Herpes Simplex Virus for Oral Squamous Cell Carcinoma [作者：Ogawa, F; Takaoka, H; Iwai, S; Aota, K; Yura, Y,期刊：Anticancer Research, 页码：3637-3645 , 文章类型： Article，,卷期：2008年28-6A] Background: The effect of dual infection with herpes simplex virus type 1 (HSV-1) mutants on human oral squamous cell carcinoma (SCC) cells was examined. Materials and Methods: Human oral SCC cells were infected with gam... Genotypic Determination by PCR-RFLP of Human Papillomavirus in Normal Oral Mucosa, Oral Leukoplakia and Oral Squamous Cell Carcinoma Samples in Madrid (Spain) [作者：Llamas-Martinez, S; Esparza-Gomez, G; Campo-Trapero, J; Cancela-Rodriguez, P; Bascones-Martinez, A; Moreno-Lopez, LA; Garcifa-Nunez, JA; Cerero-Lapiedra, R,期刊：Anticancer Research, 页码：3733-3741 , 文章类型： Article，,卷期：2008年28-6A] Background: Human papillomaviruses (HPVs), especially genotypes 16 and 18, are considered to be human carcinogens by the International Agency for Research on Cancer (IARC). They are the most important etiological agents ... The Endocannabinoid Anandamide Neither Impairs In Vitro T-Cell Function Nor Induces Regulatory T-Cell Generation [作者：Lissoni, P; Tintori, A; Fumagalli, L; Brivio, F; Messina, G; Parolini, D; Biondi, A; Balestra, A; D'Amico, G,期刊：Anticancer Research, 页码：3743-3748 , 文章类型： Article，,卷期：2008年28-6A] Background: The cannabinoids have been proposed in the treatment of cancer. Generally, the cannabinoids are believed to be useful only in the palliative therapy of cancer-related symptoms, namely pain, anorexia and cache... SUMO-1 Overexpression Increases RbAp46 Protein Stability and Suppresses Cell Growth [作者：Giri, R; Yeh, HH; Wu, CH; Liu, HS,期刊：Anticancer Research, 页码：3749-3756 , 文章类型： Article，,卷期：2008年28-6A] The retinoblastoma suppressor (Rb)-associated protein 46 (RbAp46) is a nuclear protein of 46 kDa and contains four repeats that end with Trp-Asp (VVD) residues. In this study, we reveal that the RbAp46 protein level upon... Inhibition of Hepatocellular Cancer by EB1089: In Vitro and In Vivo Study [作者：Ghous, Z; Akhter, J; Pourgholami, MH; Morris, DL,期刊：Anticancer Research, 页码：3757-3761 , 文章类型： Article，,卷期：2008年28-6A] Background: Despite significant antiproliferative potential, clinical application of 1,25 dihydroxy vitamin D-3 [1,25(OH)(2)VD3] in the treatment of cancer has been hindered due to the development of hypercalcemia. Vario... Expression of Mcm7 and Cdc6 in Oral Squamous Cell Carcinoma and Precancerous Lesions [作者：Feng, CJ; Li, HJ; Li, JN; Lu, YJ; Lia, GQ,期刊：Anticancer Research, 页码：3763-3769 , 文章类型： Article，,卷期：2008年28-6A] Background: The present study aimed at evaluating the clinical importance of Mcm7 and Cdc6 expression in oral squamous cell carcinoma (OSCC) and precancerous lesions. Materials and Methods: RT-PCR and immunohistochemistr... Correspondence between Flat Aberrant Crypt Foci and Mucin-depleted Foci in Rodent Colon Carcinogenesis [作者：Femia, AP; Paulsen, JE; Dolara, P; Alexander, J; Caderni, G,期刊：Anticancer Research, 页码：3771-3775 , 文章类型： Article，,卷期：2008年28-6A] Background: Flat aberrant crypt foci (flat ACF) and mucin-depleted foci (MDF) are preneoplastic lesions identified in the colon of carcinogen-treated rodents stained with methylene blue (MB) and high iron diamine-alcian ... Berberine Inhibits Human Neuroblastoma Cell Growth through Induction of p53-dependent Apoptosis [作者：Choi, MS; Yuk, DY; Oh, JH; Jung, HY; Han, SB; Moon, DC; Hong, JT,期刊：Anticancer Research, 页码：3777-3784 , 文章类型： Article，,卷期：2008年28-6A] Berberine, an alkaloid, has anti-tumor properties in some cancer cells, but action mechanisms are not clear yet. We here investigated the anticancer activity of berberine and possible mechanisms in human neuroblastoma SK... Effects of 5-Fluorouracil on Human Mitogen-activated Peripheral Blood Lymphocytes from Healthy Individuals [作者：Eisenthal, A; Eytan, K; Brazowski, E; Katz, BZ; Shirazi, I; Skornick, Y,期刊：Anticancer Research, 页码：3785-3791 , 文章类型： Article，,卷期：2008年28-6A] Background: The effect of 5-fluorouracil (5-FU) on activated lymphocytes was explored. Materials and Methods: The in vitro effects of 5-FU on DNA synthesis in mitogenactivated lymphocytes from healthy volunteers were com...