- Dietary Sulforaphane, a Histone Deacetylase Inhibitor for Cancer Prevention
[作者:Ho, E; Clarke, JD; Dashwood, RH,期刊:Journal of nutrition, 页码:2393-2396 , 文章类型: Article,,卷期:2009年139-12]
- The reversible acetylation of histones is an important mechanism of gene regulation. During prostate cancer progression, specific modifications in acetylation patterns on histones are apparent. Targeting the epigenome, i...
- Genistein and a Soy Extract Differentially Affect Three-Dimensional Bone Parameters and Bone-Specific Gene Expression in Ovariectomized Mice
[作者:Zhang, Y; Li, Q; Wan, HY; Helferich, WG; Wong, MS,期刊:Journal of nutrition, 页码:2230-2236 , 文章类型: Article,,卷期:2009年139-12]
- Soy isoflavone preparations, such as purified genistein and a soy extract (Novasoy), were reported previously to exert beneficial effects on bones. Our purpose in this study was to compare the effects of genistein and No...
- Dietary Soy Protein Reduces Cardiac Lipid Accumulation and the Ceramide Concentration in High-Fat Diet-Fed Rats and ob/ob Mice
[作者:Torre-Villalvazo, I; Gonzalez, F; Aguilar-Salinas, CA; Tovar, AR; Torres, N,期刊:Journal of nutrition, 页码:2237-2243 , 文章类型: Article,,卷期:2009年139-12]
- Obesity is an epidemic condition strongly associated with cardiovascular morbidity and mortality. Heart disease secondary to obesity is associated with myocardial steatosis, leading to ceramide synthesis and cell dysfunc...
- Conjugated Linoleic Acid Activates AMP-Activated Protein Kinase and Reduces Adiposity More Effectively When Used with Metformin in Mice
[作者:Jiang, S; Wang, ZG; Riethoven, JJ; Xia, YN; Miner, J; Fromm, M,期刊:Journal of nutrition, 页码:2244-2251 , 文章类型: Article,,卷期:2009年139-12]
- Trans-10, cis-12 (t10c12) conjugated linoleic acid (CLA) reduces lipid levels in adipocytes, but the mechanisms involved are still emerging. The hypotheses of this study were that t10c12 CLA treatment activated AMP-activ...
- Diallyl Trisulfide Protects Rats from Carbon Tetrachloride-Induced Liver Injury
[作者:Hosono-Fukao, T; Hosono, T; Seki, T; Ariga, T,期刊:Journal of nutrition, 页码:2252-2256 , 文章类型: Article,,卷期:2009年139-12]
- Alk(en)yl sulfides have been found to be responsible for the anticancer, antithrombotic, and antioxidant effects of garlic. We sought to identify the most potent structure of sulfides that exhibits a hepatoprotective eff...
- Reduced Milk Triglycerides in Mice Lacking Phosphoenolpyruvate Carboxykinase in Mammary Gland Adipocytes and White Adipose Tissue Contribute to the Development of Insulin Resistance in Pups
[作者:Hsieh, CW; Millward, CA; DeSantis, D; Pisano, S; Machova, J; Perales, JC; Croniger, CM,期刊:Journal of nutrition, 页码:2257-2265 , 文章类型: Article,,卷期:2009年139-12]
- Obesity and type 2 diabetes are growing problems worldwide in adults and children. In this study, we focused on understanding the patterning of insulin resistance as a result of altered perinatal nutrition. We analyzed m...
- Cardiovascular Disease Risk Biomarkers and Liver and Kidney Function Are Not Altered in Postmenopausal Women after Ingesting an Elderberry Extract Rich in Anthocyanins for 12 Weeks
[作者:Curtis, PJ; Kroon, PA; Hollands, WJ; Walls, R; Jenkins, G; Kay, CD; Cassidy, A,期刊:Journal of nutrition, 页码:2266-2271 , 文章类型: Article,,卷期:2009年139-12]
- Growing evidence supports a cardio-protective role for anthocyanins; however, there is limited evidence on their efficacy and safety following the consumption of relatively high but dietarily achievable doses in humans. ...
- Dietary Sulfur Amino Acid Supplementation Reduces Small Bowel Thiol/Disulfide Redox State and Stimulates Ileal Mucosal Growth after Massive Small Bowel Resection in Rats
[作者:Shyntum, Y; Iyer, SS; Tian, JQ; Hao, L; Mannery, YO; Jones, DP; Ziegler, TR,期刊:Journal of nutrition, 页码:2272-2278 , 文章类型: Article,,卷期:2009年139-12]
- Following massive small bowel resection in animal models, the remnant intestine undergoes a dynamic growth response termed intestinal adaptation. Cell growth and proliferation are intimately linked to cellular and extrac...
- Essential Amino Acids Increase MicroRNA-499,-208b, and-23a and Downregulate Myostatin and Myocyte Enhancer Factor 2C mRNA Expression in Human Skeletal Muscle
[作者:Drummond, MJ; Glynn, EL; Fry, CS; Dhanani, S; Volpi, E; Rasmussen, BB,期刊:Journal of nutrition, 页码:2279-2284 , 文章类型: Article,,卷期:2009年139-12]
- Essential amino acids (EAA) stimulate muscle protein synthesis in humans. However, little is known about whether microRNAs (miRNA) and genes associated with muscle growth are expressed differently following EAA ingestion...
- Cosupplementation of Isoflavones, Prenylflavonoids, and Lignans Alters Human Exposure to Phytoestrogen-Derived 17 beta-Estradiol Equivalents
[作者:Bolca, S; Wyns, C; Possemiers, S; Depypere, H; De Keukeleire, D; Bracke, M; Verstraete, W; Heyerick, A,期刊:Journal of nutrition, 页码:2293-2300 , 文章类型: Article,,卷期:2009年139-12]
- The microbial metabolism of dietary phytoestrogens varies considerably among individuals and influences the final exposure to bioactive compounds. In view of the increasing number of food supplements combining several cl...
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