- Thermosensitive hydrogel-containing polymersomes for controlled drug delivery
[作者:Lee, JS; Zhou, W; Meng, FH; Zhang, DW; Otto, C; Feijen, J,期刊:Journal of controlled release, 页码:400-408 , 文章类型: Article,,卷期:2010年146-3]
- PNIPAAm-containing polymersomes (N/Ps) were prepared by injecting a solution of poly(ethylene glycol)-b-poly(D,L-lactide) (mPEG-PDLLA) and poly(N-isopropylacrylamide) (PNIPAAm) in THF into water to incorporate PNIPAAm in...
- The role of HER2 in cancer therapy and targeted drug delivery
[作者:Tai, WY; Mahato, R; Cheng, K,期刊:Journal of controlled release, 页码:264-275 , 文章类型: Review,,卷期:2010年146-3]
- HER2 is highly expressed in a significant proportion of breast cancer, ovarian cancer, and gastric cancer. Since the discovery of its role in tumorigenesis, HERZ has received great attention in cancer research during the...
- New trends in encapsulation of liposoluble vitamins
[作者:Gonnet, M; Lethuaut, L; Boury, F,期刊:Journal of controlled release, 页码:276-290 , 文章类型: Review,,卷期:2010年146-3]
- Liposoluble vitamins (A, D, E, and K) and carotenoids have many benefits on health. They are provided mainly by foods. At pharmacological doses, they can also be used to treat skin diseases, several types of cancer or de...
- Quantitative and qualitative investigation into the impact of focused ultrasound with microbubbles on the triggered release of nanoparticles from vasculature in mouse tumors
[作者:Lin, CY; Liu, TM; Chen, CY; Huang, YL; Huang, WK; Sun, CK; Chang, FH; Lin, WL,期刊:Journal of controlled release, 页码:291-298 , 文章类型: Article,,卷期:2010年146-3]
- Ultrasound-mediated microbubble destruction may enhance the release of nanoparticles from vasculature to tumor tissues. In this study, we used four different sizes of lipid-coated CdSe quantum dot (LQD) nanoparticles ran...
- A novel lipoprotein-mimic nanocarrier composed of the modified protein and lipid for tumor cell targeting delivery
[作者:Xu, Y; Jin, XF; Ping, QN; Cheng, JA; Sun, MJ; Cao, F; You, WL; Yuan, DF,期刊:Journal of controlled release, 页码:299-308 , 文章类型: Article,,卷期:2010年146-3]
- Ursodeoxycholic acid (UA) modified protein-lipid nanocomplex (uP-LNC) as a novel biomimetic nanocarrier was developed for tumor-targeting delivery. Bovine serum albumin (BSA) was used as a model protein and its amino gro...
- Controlling physiological angiogenesis by hypoxia-induced signaling
[作者:Hadjipanayi, E; Brown, RA; Mudera, V; Deng, D; Liu, W; Cheema, U,期刊:Journal of controlled release, 页码:309-317 , 文章类型: Article,,卷期:2010年146-3]
- The full sequence of signals leading to new blood vessel formation is a physiological response to tissue hypoxia through upregulation of angiogenic factor cascades. Controlled initiation of this mechanism for therapeutic...
- Oral ileocolonic drug delivery by the colopulse-system: A bioavailability study in healthy volunteers
[作者:Schellekens, RCA; Stellaard, F; Olsder, GG; Woerdenbag, HJ; Frijlink, HW; Kosterink, JGW,期刊:Journal of controlled release, 页码:334-340 , 文章类型: Article,,卷期:2010年146-3]
- The release profile of a novel oral ileocolonic drug delivery technology (ColoPulse-technology) was assessed by a combination of conventional kinetics of a marker substance in blood and site-specific signaling by stable ...
- Biocompatible photocrosslinked poly(ester anhydride) based on functionalized poly (epsilon-caprolactone) prepolymer shows surface erosion controlled drug release in vitro and in vivo
[作者:Monkare, J; Hakala, RA; Vlasova, MA; Huotari, A; Kilpelainen, M; Kiviniemi, A; Meretoja, V; Herzig, KH; Korhonen, H; Seppala, JV; Jarvinen, K,期刊:Journal of controlled release, 页码:349-355 , 文章类型: Article,,卷期:2010年146-3]
- Star-shaped poly(E-caprolactone) oligomers functionalized with succinic anhydride were used as prepolymers to prepare photocrosslinked poly(ester anhydride) to evaluate their in vivo drug delivery functionality and bioco...
- Zero-order controlled release of ciprofloxacin-HCl from a reservoir-based, bioresorbable and elastomeric device
[作者:Tobias, IS; Lee, H; Engelmayr, GC; Macaya, D; Bettinger, CJ; Cima, MJ,期刊:Journal of controlled release, 页码:356-362 , 文章类型: Article,,卷期:2010年146-3]
- A reservoir-based device constructed of a completely biodegradable elastomer can enable several new implantation and insertion options for localized drug therapy, particularly in the case of urological therapies. We perf...
- Novel antibacterial nanofibrous PLLA scaffolds
[作者:Feng, K; Sun, HL; Bradley, MA; Dupler, EJ; Giannobile, WV; Ma, PX,期刊:Journal of controlled release, 页码:363-369 , 文章类型: Article,,卷期:2010年146-3]
- In order to achieve high local bioactivity and low systemic side.effects of antibiotics in the treatment of dental, periodontal and bone infections, a localized and temporally controlled delivery system is crucial. In th...
- Mechanically strong geopolymers offer new possibilities in treatment of chronic pain
[作者:Jamstorp, E; Forsgren, J; Bredenberg, S; Engqvist, H; Stromme, M,期刊:Journal of controlled release, 页码:370-377 , 文章类型: Article,,卷期:2010年146-3]
- We propose that a clay derived class of materials, known as geopolymers, may solve the problem of finding materials for controlled release with the right combination of properties necessary for a safe and sustained oral ...
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