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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共17条记录   Administration routes affect the quality of immune responses: A cross-sectional evaluation of particulate antigen-delivery systems [作者：Mohanan, D; Slutter, B; Henriksen-Lacey, M; Jiskoot, W; Bouwstra, JA; Perrie, Y; Kundig, TM; Gander, B; Johansen, P,期刊：Journal of controlled release, 页码：342-349 , 文章类型： Article，,卷期：2010年147-3] Particulate delivery systems such as liposomes and polymeric nano- and microparticles are attracting great interest for developing new vaccines. Materials and formulation properties essential for this purpose have been e... Effect of injection site on in situ implant formation and drug release in vivo [作者：Patel, RB; Solorio, L; Wu, HP; Krupka, T; Exner, AA,期刊：Journal of controlled release, 页码：350-358 , 文章类型： Article，,卷期：2010年147-3] In situ forming drug delivery implants offer an attractive alternative to pre-formed implant devices for local drug delivery due to their ability to deliver fragile drugs, simple manufacturing process, and less invasive ... Sustained delivery of human growth hormone using a polyelectrolyte complex-loaded thermosensitive polyphosphazene hydrogel [作者：Park, MR; Chun, CJ; Ahn, SW; Ki, MH; Cho, CS; Song, SC,期刊：Journal of controlled release, 页码：359-367 , 文章类型： Article，,卷期：2010年147-3] A combined system of polyelectrolyte complex (PEC) and injectable, biodegradable and thermosensitive poly(organophosphazene) hydrogel has been suggested as an injectable depot for a controlled and sustained delivery of h... Sunlight triggered photodynamic ultradeformable liposomes against Leishmania braziliensis are also leishmanicidal in the dark [作者：Montanari, J; Maidana, C; Esteva, MI; Salomon, C; Morilla, MJ; Romero, EL,期刊：Journal of controlled release, 页码：368-376 , 文章类型： Article，,卷期：2010年147-3] Being independent of artificial power sources, self administered sunlight triggered photodynamic therapy could be a suitable alternative treatment for cutaneous leishmaniasis, that avoids the need for injectables and the... Cyclodextrin complexed insulin encapsulated hydrogel microparticles: An oral delivery system for insulin [作者：Sajeesh, S; Bouchemal, K; Marsaud, V; Vauthier, C; Sharma, CP,期刊：Journal of controlled release, 页码：377-384 , 文章类型： Article，,卷期：2010年147-3] An oral insulin delivery system based on methyl-beta-cyclodextrin (MCD) complexed insulin encapsulated polymethacrylic acid (PMAA) hydrogel microparticles was evaluated in this investigation. Poly(methacrylic acid)-chito... mRNA transfection of cervical carcinoma and mesenchymal stem cells mediated by cationic carriers [作者：Rejman, J; Tavernier, G; Bavarsad, N; Demeester, J; De Smedt, SC,期刊：Journal of controlled release, 页码：385-391 , 文章类型： Article，,卷期：2010年147-3] Messenger RNA encoding luciferase (mLUC) was complexed to the cationic lipids Lipofectamine or DOTAP/DOPE, and to the cationic polymer linear poly(ethyleneimine) (linPEI). The complexes were incubated with HeLa cells and... Self-assembling peptide nanofiber scaffolds for controlled release governed by gelator design and guest size [作者：Zhao, Y; Tanaka, M; Kinoshita, T; Higuchi, M; Tan, TW,期刊：Journal of controlled release, 页码：392-399 , 文章类型： Article，,卷期：2010年147-3] The aim of this study was to develop controlled drug delivery by network scaffolds based on self-assembling peptide RADAFI and RADAFII. These two peptides self-assembled into interconnected nanofibrilar network structure... Device-based local delivery of siRNA against mammalian target of rapamycin (mTOR) in a murine subcutaneous implant model to inhibit fibrous encapsulation [作者：Takahashi, H; Wang, YW; Grainger, DW,期刊：Journal of controlled release, 页码：400-407 , 文章类型： Article，,卷期：2010年147-3] Fibrous encapsulation of surgically implanted devices is associated with elevated proliferation and activation of fibroblasts in tissues surrounding these implants, frequently causing foreign body complications. Here we ... Polymer particle shape independently influences binding and internalization by macrophages [作者：Sharma, G; Valenta, DT; Altman, Y; Harvey, S; Xie, H; Mitragotri, S; Smith, JW,期刊：Journal of controlled release, 页码：408-412 , 文章类型： Article，,卷期：2010年147-3] The interaction of macrophages with micro and nanoparticles (MNPs) is important because these cells clear particles from the circulation, and because they are potential therapeutic targets in inflammatory conditions, ath... Polymersomes of asymmetric bilayer membrane formed by phase-guided assembly [作者：Zhang, YL; Wu, F; Yuan, WE; Jin, T,期刊：Journal of controlled release, 页码：413-419 , 文章类型： Article，,卷期：2010年147-3] Encapsulating delicate biomolecules into submicron-sized polymer particulate systems with preserved native conformation and sufficient loading efficiency is of great challenge. To address this issue, we developed a uniqu... Intracellular delivery and anti-cancer effect of self-assembled heparin-Pluronic nanogels with RNase A [作者：Choi, JH; Jang, JY; Joung, YK; Kwon, MH; Park, KD,期刊：Journal of controlled release, 页码：420-427 , 文章类型： Article，,卷期：2010年147-3] A novel self-assembled nanogel was prepared for the intracellular delivery of ribonuclease A (RNase A) and the anti-cancer efficacy of RNase A delivery was investigated. The physical properties of self-assembled heparin-... A simple method to achieve high doxorubicin loading in biodegradable polymersomes [作者：Sanson, C; Schatz, C; Le Meins, JF; Soum, A; Thevenot, J; Garanger, E; Lecommandoux, S,期刊：Journal of controlled release, 页码：428-435 , 文章类型： Article，,卷期：2010年147-3] Doxorubicin (Dox), an anthracycline anticancer drug, was successfully incorporated into block copolymer vesicles of poly(trimethylene carbonate)-b-poly(L-glutamic acid) (PTMC-b-PGA) by a solvent-displacement (nanoprecipi... Size of thermosensitive liposomes influences content release [作者：Hossann, M; Wang, TT; Wiggenhorn, M; Schmidt, R; Zengerle, A; Winter, G; Eibl, H; Peller, M; Reiser, M; Issels, RD; Lindner, LH,期刊：Journal of controlled release, 页码：436-443 , 文章类型： Article，,卷期：2010年147-3] Thermosensitive liposomes (TSL) in combination with regional hyperthermia represent a powerful tool for tumor specific drug delivery. The objective of this study was to investigate the influence of vesicle size on the bi... Effect of shape and size of polymer particles on cellular internalization [作者：Park, K,期刊：Journal of controlled release, 页码：313-313 , 文章类型： Editorial Material，,卷期：2010年147-3] Drug delivery system based on chronobiology-A review [作者：Mandal, AS; Biswas, N; Karim, KM; Guha, A; Chatterjee, S; Behera, M; Kuotsu, K,期刊：Journal of controlled release, 页码：314-325 , 文章类型： Review，,卷期：2010年147-3] With the advancement in the field of chronobiology, modern drug delivery approaches have been elevated to a new concept of chronopharmacology i.e. the ability to deliver the therapeutic agent to a patient in a staggered ... Dose sparing enabled by skin immunization with influenza virus-like particle vaccine using microneedles [作者：Quan, FS; Kim, YC; Compans, RW; Prausnitz, MR; Kang, SM,期刊：Journal of controlled release, 页码：326-332 , 文章类型： Article，,卷期：2010年147-3] To address the limitations of conventional influenza vaccine manufacturing and delivery, this study investigated administration of virus-like particle (VLP) influenza vaccine using a microneedle patch. The goal was to de...